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English
CD8 lineage commitment in the absence of CD8.
scientific article published on May 1997
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Statements
instance of
scholarly article
1 reference
stated in
Q5412157
PMCID
2782926
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9175841%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
title
CD8 lineage commitment in the absence of CD8
(English)
1 reference
stated in
Q5412157
PMCID
2782926
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9175841%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
main subject
cell fate commitment
1 reference
based on heuristic
inferred from title
author
Kristin A. Hogquist
series ordinal
2
1 reference
stated in
Q5412157
PMCID
2782926
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9175841%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
author name string
A W Goldrath
series ordinal
1
1 reference
stated in
Q5412157
PMCID
2782926
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9175841%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
M J Bevan
series ordinal
3
1 reference
stated in
Q5412157
PMCID
2782926
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9175841%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
language of work or name
English
0 references
publication date
1 May 1997
1 reference
stated in
Q5412157
PMCID
2782926
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9175841%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
published in
Immunity
1 reference
stated in
Q5412157
PMCID
2782926
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9175841%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
volume
6
1 reference
stated in
Q5412157
PMCID
2782926
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9175841%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
page(s)
633-642
1 reference
stated in
Q5412157
PMCID
2782926
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9175841%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
issue
5
1 reference
stated in
Q5412157
PMCID
2782926
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9175841%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
cites work
CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding
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stated in
PubMed Central
reference URL
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23 August 2017
The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells
1 reference
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23 August 2017
Antigen presentation and T cell development in H2-M-deficient mice
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23 August 2017
H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection
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PubMed Central
reference URL
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23 August 2017
Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway
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reference URL
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23 August 2017
Role of CD4 and CD8 in T cell activation and differentiation
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23 August 2017
Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cells
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23 August 2017
Positive selection of CD8+ T cells induced by major histocompatibility complex binding peptides in fetal thymic organ culture
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stated in
PubMed Central
reference URL
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23 August 2017
Evidence for differential intracellular signaling via CD4 and CD8 molecules
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
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23 August 2017
T cell receptor antagonist peptides induce positive selection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
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23 August 2017
Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
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23 August 2017
Disruption of T lymphocyte positive and negative selection in mice lacking the CD8 beta chain
1 reference
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PubMed Central
reference URL
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23 August 2017
Interaction between CD8 and major histocompatibility complex (MHC) class I mediated by multiple contact surfaces that include the alpha 2 and alpha 3 domains of MHC class I.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
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23 August 2017
A single amino acid substitution in the alpha 3 domain of an H-2 class I molecule abrogates reactivity with CTL.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
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23 August 2017
The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
23 August 2017
Molecular biology and function of CD4 and CD8
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
23 August 2017
Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
23 August 2017
CD8 is needed for development of cytotoxic T cells but not helper T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
23 August 2017
The CD8 coreceptor revisited: one chain good, two chains better
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
14 September 2017
CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
28 September 2017
T-cell-receptor affinity and thymocyte positive selection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
28 September 2017
Analysis of coreceptor versus accessory molecule function of CD8 as a correlate of exogenous peptide concentration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
28 September 2017
The alpha beta T cell receptor can replace the gamma delta receptor in the development of gamma delta lineage cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
26 June 2018
Turnover of naive- and memory-phenotype T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
26 June 2018
Reduced thymic maturation but normal effector function of CD8+ T cells in CD8 beta gene-targeted mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
26 June 2018
Specificity and flexibility in thymic selection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
26 June 2018
Positive selection of CD4+ T cells by TCR ligation without aggregation even in the absence of MHC.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
26 June 2018
Intrathymic T cell receptor (TcR) targeting in mice lacking CD4 or major histocompatibility complex (MHC) class II: rescue of CD4 T cell lineage without co-engagement of TcR/CD4 by MHC class II.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
26 June 2018
The CD4/CD8:p56lck complex in T lymphocytes: a potential mechanism to regulate T-cell growth.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
26 June 2018
Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
26 June 2018
Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
26 June 2018
A binding site for the T-cell co-receptor CD8 on the alpha 3 domain of HLA-A2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
26 June 2018
MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
2 September 2018
The repertoire of T cells shaped by a single MHC/peptide ligand.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
2 September 2018
Helper T cells without CD4: control of leishmaniasis in CD4-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
2 September 2018
Class II major histocompatibility complex-restricted T cell function in CD4-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
2 September 2018
A role for the cytoplasmic tail of the beta chain of CD8 in thymic selection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
2 September 2018
Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
2 September 2018
T cell development in CD8-/- mice. Thymic positive selection is biased toward the helper phenotype.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
2 September 2018
Peptide antagonists that promote positive selection are inefficient at T cell activation and thymocyte deletion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
3 December 2018
CD8 modulation of T-cell antigen receptor–ligand interactions on living cytotoxic T lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2782926
retrieved
3 December 2018
Strong agonist ligands for the T cell receptor do not mediate positive selection of functional CD8+ T cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9175841
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The lack of CD8 alpha cytoplasmic domain resulted in a dramatic decrease in efficiency in thymic maturation but only a moderate reduction in cytotoxic function of CD8+ T lymphocytes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9175841
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Participation of CD4 coreceptor molecules in T-cell repertoire selection
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9175841
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9175841
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
T cell receptor targeting to thymic cortical epithelial cells in vivo induces survival, activation and differentiation of immature thymocytes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9175841
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/S1074-7613(00)80351-9
1 reference
stated in
Q5412157
PMCID
2782926
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9175841%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
Fatcat ID
release_53f5a3cymfh5phserghr3yg7sm
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/53f5a3cymfh5phserghr3yg7sm
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMCID
2782926
1 reference
stated in
Q5412157
PMCID
2782926
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9175841%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
PubMed ID
9175841
1 reference
stated in
Q5412157
PMCID
2782926
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9175841%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
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