(Q37437251)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19352540%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

review article

1 reference

title

Regulation of TGF-beta signaling by Smad7 (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19352540%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19352540%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

Ziying Liu

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19352540%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Yeguang Chen

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19352540%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

publication date

1 April 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19352540%20AND%20SRC:MED&resulttype=core&format=json

Acta Biochimica et Biophysica Sinica

25 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19352540%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

volume

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19352540%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

issue

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19352540%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

page(s)

263-272

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19352540%20AND%20SRC:MED&resulttype=core&format=json

Mechanism of TGFbeta receptor inhibition by FKBP12

25 January 2020

cites work

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12 December 2020

Smad7 as a therapeutic agent for chronic kidney diseases.

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12 December 2020

AIP4 restricts transforming growth factor-beta signaling through a ubiquitination-independent mechanism

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12 December 2020

Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosis

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12 December 2020

Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1.

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12 December 2020

STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signaling

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12 December 2020

Transforming growth factor beta-dependent sequential activation of Smad, Bim, and caspase-9 mediates physiological apoptosis in gastric epithelial cells

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12 December 2020

Stable overexpression of Smad7 in human melanoma cells inhibits their tumorigenicity in vitro and in vivo

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12 December 2020

Smad7-induced beta-catenin degradation alters epidermal appendage development

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12 December 2020

Fine tuning and cross-talking of TGF-beta signal by inhibitory Smads

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12 December 2020

Crk-associated substrate lymphocyte type regulates transforming growth factor-beta signaling by inhibiting Smad6 and Smad7

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12 December 2020

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12 December 2020

Dual role for TGF-beta1 in apoptosis

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12 December 2020

Extracellular control of TGFbeta signalling in vascular development and disease

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12 December 2020

Smad6 as a transcriptional corepressor

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12 December 2020

TGFbeta induces SIK to negatively regulate type I receptor kinase signaling.

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12 December 2020

TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA

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12 December 2020

Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55

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12 December 2020

Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

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12 December 2020

Bone morphogenetic protein 2 activates Smad6 gene transcription through bone-specific transcription factor Runx2

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12 December 2020

TGF-beta: a master of all T cell trades

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12 December 2020

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12 December 2020

Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signaling

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12 December 2020

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

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12 December 2020

Smad7 in TGF-beta-mediated negative regulation of gut inflammation

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12 December 2020

Smad7 is required for TGF-beta-induced activation of the small GTPase Cdc42.

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12 December 2020

Synergism between transcription factors TFE3 and Smad3 in transforming growth factor-beta-induced transcription of the Smad7 gene

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12 December 2020

The Smad6-histone deacetylase 3 complex silences the transcriptional activity of the glucocorticoid receptor: potential clinical implications

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12 December 2020

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

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12 December 2020

Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3

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12 December 2020

Blockade of NFkappaB activation and renal inflammation by ultrasound-mediated gene transfer of Smad7 in rat remnant kidney.

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12 December 2020

Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation

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12 December 2020

Negative regulation of TGF-beta receptor/Smad signal transduction.

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12 December 2020

Ultraviolet irradiation induces Smad7 via induction of transcription factor AP-1 in human skin fibroblasts

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12 December 2020

Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia

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12 December 2020

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

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12 December 2020

Smad6 recruits transcription corepressor CtBP to repress bone morphogenetic protein-induced transcription

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12 December 2020

Smad7 but not Smad6 cooperates with oncogenic ras to cause malignant conversion in a mouse model for squamous cell carcinoma.

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12 December 2020

Smad7 and protein phosphatase 1alpha are critical determinants in the duration of TGF-beta/ALK1 signaling in endothelial cells.

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12 December 2020

Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway

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12 December 2020

TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development

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12 December 2020

Smad7 Inhibits chondrocyte differentiation at multiple steps during endochondral bone formation and down-regulates p38 MAPK pathways

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12 December 2020

Jab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradation

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12 December 2020

Smad7 induces tumorigenicity by blocking TGF-beta-induced growth inhibition and apoptosis.

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12 December 2020

Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells

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12 December 2020

Regulation of collagen synthesis by inhibitory Smad7 in cardiac myofibroblasts

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12 December 2020

Blockade of the TGF-beta superfamily by Smad7: breaking a link in the metastatic chain

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12 December 2020

SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation

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12 December 2020

Activated hepatic stellate cells induce tumor progression of neoplastic hepatocytes in a TGF-beta dependent fashion

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12 December 2020

Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling

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12 December 2020

Transforming growth factor-beta and Smad signalling in kidney diseases.

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12 December 2020

A nuclear antagonistic mechanism of inhibitory Smads in transforming growth factor-beta signaling

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12 December 2020

GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor

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12 December 2020

Signaling mechanism of TGF-beta1 in prevention of renal inflammation: role of Smad7.

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12 December 2020

Differentiation plasticity regulated by TGF-beta family proteins in development and disease

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12 December 2020

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12 December 2020

Efficient TGF-beta induction of the Smad7 gene requires cooperation between AP-1, Sp1, and Smad proteins on the mouse Smad7 promoter

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12 December 2020

A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk

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12 December 2020

Repression of endogenous Smad7 by Ski.

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12 December 2020

A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling

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12 December 2020

Smad7 binds to the adaptors TAB2 and TAB3 to block recruitment of the kinase TAK1 to the adaptor TRAF2.

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12 December 2020

TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

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12 December 2020

Distinct roles of individual Smads in skin carcinogenesis

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12 December 2020

Smad3 as a mediator of the fibrotic response

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12 December 2020

Smad7 stabilizes beta-catenin binding to E-cadherin complex and promotes cell-cell adhesion

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12 December 2020

A Failure of Transforming Growth Factor-β1 Negative Regulation Maintains Sustained NF-κB Activation in Gut Inflammation

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12 December 2020

Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms

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12 December 2020

FKBP12 functions as an adaptor of the Smad7-Smurf1 complex on activin type I receptor

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12 December 2020

OAZ regulates bone morphogenetic protein signaling through Smad6 activation

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12 December 2020

Expression of Smad4 and Smad7 in human thyroid follicular carcinoma cell lines.

1 reference

12 December 2020

The N domain of Smad7 is essential for specific inhibition of transforming growth factor-beta signaling

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12 December 2020

Mechanisms of TGF-beta-mediated apoptosis

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12 December 2020

A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

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12 December 2020

The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer

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12 December 2020

Severe acute respiratory syndrome-associated coronavirus nucleocapsid protein interacts with Smad3 and modulates transforming growth factor-beta signaling

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12 December 2020

Transforming growth factor-beta regulation of immune responses

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12 December 2020

Evidence for a role of the JNK cascade in Smad7-mediated apoptosis

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12 December 2020

Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours

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12 December 2020

Stable Overexpression of Smad7 in Human Melanoma Cells Impairs Bone Metastasis

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12 December 2020

Control of Smad7 stability by competition between acetylation and ubiquitination

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12 December 2020

Study of interaction between Smad7 and DNA by single-molecule force spectroscopy

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12 December 2020

The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

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12 December 2020

Latent transforming growth factor-beta binding protein domains involved in activation and transglutaminase-dependent cross-linking of latent transforming growth factor-beta

1 reference

12 December 2020

Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease

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12 December 2020

Overexpression of the TGF-beta antagonist Smad7 in endometrial cancer

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12 December 2020

The balance between acetylation and deacetylation controls Smad7 stability.

1 reference

12 December 2020

Identifiers

DOI

10.1093/ABBS/GMP018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19352540%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

PMC publication ID

7110000

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19352540%20AND%20SRC:MED&resulttype=core&format=json