(Q52577959)

3 May 2018

title

Smad7 binds to the adaptors TAB2 and TAB3 to block recruitment of the kinase TAK1 to the adaptor TRAF2. (English)

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3 May 2018

author name string

Suntaek Hong

1

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3 May 2018

Seunghwan Lim

2

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3 May 2018

Allen G Li

3

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3 May 2018

Chan Lee

4

1 reference

3 May 2018

Youn Sook Lee

5

1 reference

3 May 2018

Eun-Kyung Lee

6

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3 May 2018

Seok Hee Park

7

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3 May 2018

Xiao-Jing Wang

8

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3 May 2018

Seong-Jin Kim

9

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3 May 2018

language of work or name

English

0 references

publication date

25 March 2007

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3 May 2018

published in

Nature Immunology

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3 May 2018

volume

8

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3 May 2018

issue

5

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3 May 2018

page(s)

504-513

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3 May 2018

TNF-R1 signaling: a beautiful pathway

cites work

1 reference

7 January 2021

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

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7 January 2021

The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation

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7 January 2021

NF-kappaB functions as a tumour promoter in inflammation-associated cancer

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7 January 2021

Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression

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7 January 2021

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

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7 January 2021

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

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7 January 2021

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

1 reference

7 January 2021

TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway

1 reference

7 January 2021

Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling

1 reference

7 January 2021

Smad transcription factors

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7 January 2021

TGF beta signals through a heteromeric protein kinase receptor complex

1 reference

7 January 2021

Negative regulation of cytokine signaling influences inflammation

1 reference

7 January 2021

Signaling mechanism of TGF-beta1 in prevention of renal inflammation: role of Smad7.

1 reference

7 January 2021

Transforming growth factor beta 1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype

1 reference

7 January 2021

1 reference

7 January 2021

Smad3 and Smad4 mediate transcriptional activation of the human Smad7 promoter by transforming growth factor beta

1 reference

7 January 2021

Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway.

1 reference

7 January 2021

Inhibition of the transforming growth factor beta (TGFbeta) pathway by interleukin-1beta is mediated through TGFbeta-activated kinase 1 phosphorylation of SMAD3.

1 reference

7 January 2021

Phosphorylation of Smad7 at Ser-249 does not interfere with its inhibitory role in transforming growth factor-beta-dependent signaling but affects Smad7-dependent transcriptional activation

1 reference

7 January 2021

Evidence for a role of the JNK cascade in Smad7-mediated apoptosis

1 reference

7 January 2021

Smad7 inhibits the survival nuclear factor kappaB and potentiates apoptosis in epithelial cells

1 reference

7 January 2021

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

7 January 2021

Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1.

1 reference

7 January 2021

Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-beta-induced gene expression

1 reference

7 January 2021

Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

1 reference

7 January 2021

Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB.

1 reference

7 January 2021

Ubiquitination of RIP Is Required for Tumor Necrosis Factor α-induced NF-κB Activation

1 reference

7 January 2021

Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues

1 reference

7 January 2021

Apoptosis in podocytes induced by TGF-beta and Smad7

1 reference

7 January 2021

Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death

1 reference

7 January 2021

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

1 reference

7 January 2021

Spontaneously increased production of nitric oxide and aberrant expression of the inducible nitric oxide synthase in vivo in the transforming growth factor beta 1 null mouse

1 reference

7 January 2021

Dysregulation of IFN-gamma signaling pathways in the absence of TGF-beta 1

1 reference

7 January 2021

NF-kappaB regulation in the immune system

1 reference

7 January 2021

The I kappa B/NF-kappa B system: a key determinant of mucosalinflammation and protection

1 reference

7 January 2021

Nuclear factor-kappa B in rheumatoid synovium. Localization of p50 and p65

1 reference

7 January 2021

TGF beta 1 inhibits NF-kappa B/Rel activity inducing apoptosis of B cells: transcriptional activation of I kappa B alpha

1 reference

7 January 2021

Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease

1 reference

7 January 2021

Deficient Smad7 expression: a putative molecular defect in scleroderma

1 reference

7 January 2021

Impaired Smad7-Smurf-mediated negative regulation of TGF-beta signaling in scleroderma fibroblasts

1 reference

7 January 2021

Smad7 mediates apoptosis induced by transforming growth factor beta in prostatic carcinoma cells

1 reference

7 January 2021

Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone.

1 reference

7 January 2021

Identifiers

DOI

10.1038/NI1451

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3 May 2018

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3 May 2018