(Q37438563)

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Systemic inhibition of transforming growth factor-beta in glioma-bearing mice improves the therapeutic efficacy of glioma-associated antigen peptide vaccines

scientific article published on 27 October 2009

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11 February 2020

Systemic inhibition of transforming growth factor-beta in glioma-bearing mice improves the therapeutic efficacy of glioma-associated antigen peptide vaccines (English)

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11 February 2020

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11 February 2020

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11 February 2020

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Hideho Okada

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11 February 2020

author name string

Ryo Ueda

1

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11 February 2020

Xinmei Zhu

3

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11 February 2020

Kotaro Sasaki

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11 February 2020

Edward R Kastenhuber

5

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11 February 2020

Heather A McDonald

7

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11 February 2020

Jay Harper

8

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11 February 2020

Scott Lonning

9

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11 February 2020

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27 October 2009

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11 February 2020

Clinical Cancer Research

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11 February 2020

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11 February 2020

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11 February 2020

6551-6559

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11 February 2020

Immunotherapeutic approaches for glioma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783346

23 August 2017

Systemic blockade of transforming growth factor-beta signaling augments the efficacy of immunogene therapy

1 reference

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23 August 2017

Transforming growth factor-beta receptor blockade augments the effectiveness of adoptive T-cell therapy of established solid cancers

1 reference

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23 August 2017

Transforming growth factor beta subverts the immune system into directly promoting tumor growth through interleukin-17

1 reference

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23 August 2017

An anti-transforming growth factor beta antibody suppresses metastasis via cooperative effects on multiple cell compartments.

1 reference

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23 August 2017

Molecular strategies for the treatment of malignant glioma--genes, viruses, and vaccines

1 reference

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23 August 2017

Induction of protective and therapeutic antitumor immunity by a DNA vaccine with a glioma antigen, SOX6.

1 reference

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23 August 2017

Transforming growth factor-beta signaling in cancer invasion and metastasis

1 reference

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23 August 2017

Toll like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models

1 reference

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23 August 2017

Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms

1 reference

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23 August 2017

Dysregulation of IL-15-mediated T-cell homeostasis in TGF-beta dominant-negative receptor transgenic mice

1 reference

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23 August 2017

Specificity and versatility in tgf-beta signaling through Smads

1 reference

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23 August 2017

Identification of a glioma antigen, GARC-1, using cytotoxic T lymphocytes induced by HSV cancer vaccine

1 reference

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23 August 2017

Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells

1 reference

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23 August 2017

Role of transforming growth factor Beta in human cancer

1 reference

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23 August 2017

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

1 reference

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23 August 2017

Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo

1 reference

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23 August 2017

Vaccination with EphA2-derived T cell-epitopes promotes immunity against both EphA2-expressing and EphA2-negative tumors

1 reference

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23 August 2017

Interleukin-12 and the regulation of innate resistance and adaptive immunity

1 reference

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23 August 2017

Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells

1 reference

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23 August 2017

Inhibition of cytotoxic T cell development by transforming growth factor beta and reversal by recombinant tumor necrosis factor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783346

23 August 2017

Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics

1 reference

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14 September 2017

Inhibition of STAT3 promotes the efficacy of adoptive transfer therapy using type-1 CTLs by modulation of the immunological microenvironment in a murine intracranial glioma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783346

14 September 2017

Tumor evasion of the immune system by converting CD4+CD25- T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta

1 reference

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14 September 2017

Identification of interleukin-13 receptor alpha2 peptide analogues capable of inducing improved antiglioma CTL responses.

1 reference

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14 September 2017

TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance

1 reference

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14 September 2017

Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment

1 reference

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14 September 2017

SD-208, a novel transforming growth factor beta receptor I kinase inhibitor, inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo

1 reference

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14 September 2017

Immunotherapeutic targeting of shared melanoma-associated antigens in a murine glioma model

1 reference

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14 September 2017

Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes

1 reference

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14 September 2017

A novel small-molecule inhibitor of transforming growth factor beta type I receptor kinase (SM16) inhibits murine mesothelioma tumor growth in vivo and prevents tumor recurrence after surgical resection.

1 reference

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26 June 2018

Differential expression of transforming growth factor-beta 1, -beta 2, and -beta 3 by glioblastoma cells, astrocytes, and microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783346

26 June 2018

Effect of the expression of transforming growth factor-beta 2 in primary human glioblastomas on immunosuppression and loss of immune surveillance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783346

26 June 2018

Factors, including transforming growth factor beta, released in the glioblastoma residual cavity, impair activity of adherent lymphokine-activated killer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783346

27 July 2018

CD4+FoxP3+ regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783346

2 September 2018

TGF-beta2 inhibition augments the effect of tumor vaccine and improves the survival of animals with pre-established brain tumors.

1 reference

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2 September 2018

Adoptive transfer of type 1 CTL mediates effective anti-central nervous system tumor response: critical roles of IFN-inducible protein-10.

1 reference

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2 September 2018

Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma.

1 reference

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2 September 2018

Transforming growth factor beta inhibits the antigen-presenting functions and antitumor activity of dendritic cell vaccines

1 reference

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1 reference

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2 September 2018

The effect of transforming growth factor-beta 2-specific phosphorothioate-anti-sense oligodeoxynucleotides in reversing cellular immunosuppression in malignant glioma.

1 reference

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2 September 2018

Immunosuppression and transforming growth factor-beta in glioblastoma. Preferential production of transforming growth factor-beta 2.

1 reference

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2 September 2018

What can stochastic resonance do?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19861464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-beta contributes to the shift toward Th2-type responses through direct and IL-10-mediated pathways in tumor-bearing mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19861464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downregulation of interleukin-12 (IL-12) responsiveness in human T cells by transforming growth factor-beta: relationship with IL-12 signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/19861464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiplexed immunobead-based cytokine profiling for early detection of ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19861464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of transforming growth factor beta on the functions of natural killer cells: depressed cytolytic activity and blunting of interferon responsiveness

1 reference

https://pubmed.ncbi.nlm.nih.gov/19861464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibodies recognizing transforming growth factor-beta. Bioactivity neutralization and transforming growth factor beta 2 affinity purification

1 reference

https://pubmed.ncbi.nlm.nih.gov/19861464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain tumor therapy by combined vaccination and antisense oligonucleotide delivery with nanoparticles

1 reference

https://pubmed.ncbi.nlm.nih.gov/19861464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preferential expression of very late antigen-4 on type 1 CTL cells plays a critical role in trafficking into central nervous system tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19861464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-09-1067

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19861464%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19861464%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

Europe PubMed Central

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11 February 2020

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