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Wnt/Fz signaling and the cytoskeleton: potential roles in tumorigenesis.
scientific article published on May 2009
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scholarly article
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Europe PubMed Central
PubMed publication ID
19365405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19365405%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
review article
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Europe PubMed Central
title
Wnt/Fz signaling and the cytoskeleton: potential roles in tumorigenesis
(English)
1 reference
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Europe PubMed Central
PubMed publication ID
19365405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19365405%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
main subject
cytoskeleton
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author
Randall T. Moon
series ordinal
3
1 reference
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Europe PubMed Central
PubMed publication ID
19365405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19365405%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
author name string
Shih-Lei Lai
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1
1 reference
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Europe PubMed Central
PubMed publication ID
19365405
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19365405%20AND%20SRC:MED&resulttype=core&format=json
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25 January 2020
Andy J Chien
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2
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Europe PubMed Central
PubMed publication ID
19365405
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25 January 2020
publication date
1 May 2009
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PubMed publication ID
19365405
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retrieved
25 January 2020
published in
Cell Research
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stated in
Europe PubMed Central
PubMed publication ID
19365405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19365405%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
volume
19
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Europe PubMed Central
PubMed publication ID
19365405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19365405%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
issue
5
1 reference
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Europe PubMed Central
PubMed publication ID
19365405
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retrieved
25 January 2020
page(s)
532-545
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Europe PubMed Central
PubMed publication ID
19365405
reference URL
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retrieved
25 January 2020
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Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation
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AMER1 regulates the distribution of the tumor suppressor APC between microtubules and the plasma membrane
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Wnt signalling and the actin cytoskeleton
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Mutated APC and Asef are involved in the migration of colorectal tumour cells
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Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1
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Zebrafish Rho kinase 2 acts downstream of Wnt11 to mediate cell polarity and effective convergence and extension movements
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Profilin is an effector for Daam1 in non-canonical Wnt signaling and is required for vertebrate gastrulation
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Daam1 regulates the endocytosis of EphB during the convergent extension of the zebrafish notochord
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
EphB/EphrinB receptors and Wnt signaling in colorectal cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RhoA acts downstream of Wnt5 and Wnt11 to regulate convergence and extension movements by involving effectors Rho kinase and Diaphanous: use of zebrafish as an in vivo model for GTPase signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho mediates cytokinesis and epiboly via ROCK in zebrafish.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitf regulation of Dia1 controls melanoma proliferation and invasiveness
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonrandom 4p13 rearrangements of the RhoH/TTF gene, encoding a GTP-binding protein, in non-Hodgkin's lymphoma and multiple myeloma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genomic analysis of metastasis reveals an essential role for RhoC
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho GTPases: potential candidates for anticancer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho GTPase expression in tumourigenesis: evidence for a significant link
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of NFAT transcription factors in integrin-mediated carcinoma invasion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
APC mutations occur early during colorectal tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Balancing cell adhesion and Wnt signaling, the key role of beta-catenin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of E-cadherin/Catenin association by tyrosine phosphorylation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Single amino acid substitutions in proteins of the armadillo gene family abolish their binding to alpha-catenin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the Dimerization and β-Catenin- Binding Region of α-Catenin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of beta-catenin structure and activity by tyrosine phosphorylation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta-catenin N- and C-terminal tails modulate the coordinated binding of adherens junction proteins to beta-catenin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational analysis of the tyrosine phosphatome in colorectal cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Src kinase signaling in leukaemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Src kinase and pancreatic cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of a beta-catenin/Tcf complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hot spots in beta-catenin for interactions with LEF-1, conductin and APC
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E-Cadherin Suppresses Cellular Transformation by Inhibiting β-Catenin Signaling in an Adhesion-Independent Manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glypican-3 regulates migration, adhesion and actin cytoskeleton organization in mammary tumor cells through Wnt signaling modulation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mel-CAM-specific genetic suppressor elements inhibit melanoma growth and invasion through loss of gap junctional communication.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Desmosomes: a role in cancer?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Desmosomes: new perspectives on a classic
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Working out the strength and flexibility of desmosomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anterior axis duplication in Xenopus induced by the over-expression of the cadherin-binding protein plakoglobin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nr-CAM is a target gene of the beta-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytoplasmically anchored plakoglobin induces a WNT-like phenotype in Xenopus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcriptional factor Tcf-4 contains different binding sites for beta-catenin and plakoglobin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tyrosine Phosphorylation of Plakoglobin Causes Contrary Effects on Its Association with Desmosomes and Adherens Junction Components and Modulates β-Catenin-Mediated Transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Desmoglein 2 is expressed abnormally rather than mutated in familial and sporadic gastric cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased expression of the adhesion molecule desmoglein-2 is associated with diffuse-type gastric carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Desmocollin switching in colorectal cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epigenetic silencing of DSC3 is a common event in human breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bardet-Biedl syndrome: an emerging pathomechanism of intracellular transport.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCR.2009.41
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/CR.2009.41
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19365405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19365405%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
PubMed publication ID
19365405
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19365405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19365405%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
ResearchGate publication ID
24276612
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