(Q37454208)

English

Gene related to anergy in lymphocytes (GRAIL) expression in CD4+ T cells impairs actin cytoskeletal organization during T cell/antigen-presenting cell interactions

scientific article published on 15 October 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Gene related to anergy in lymphocytes (GRAIL) expression in CD4+ T cells impairs actin cytoskeletal organization during T cell/antigen-presenting cell interactions (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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Anna Huttenlocher

5

object named as

Anna Huttenlocher

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

author name string

Jill M Schartner

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

William T Simonson

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Sarah A Wernimont

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Lauren M Nettenstrom

4

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Christine M Seroogy

6

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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publication date

15 October 2009

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Europe PubMed Central

PMC publication ID

20 August 2017

number of pages

8

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Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

20 August 2017

284

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

50

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Europe PubMed Central

PMC publication ID

20 August 2017

34674-34681

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2787330/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Th2 cell hyporesponsiveness during chronic murine schistosomiasis is cell intrinsic and linked to GRAIL expression

1 reference

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Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function

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Effects of intracellular calcium and actin cytoskeleton on TCR mobility measured by fluorescence recovery

1 reference

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Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation

1 reference

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The actin cytoskeleton in T cell activation

1 reference

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Preservation of self: an overview of E3 ubiquitin ligases and T cell tolerance

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GRAIL is up-regulated in CD4+ CD25+ T regulatory cells and is sufficient for conversion of T cells to a regulatory phenotype

1 reference

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An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55R

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Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

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GRAIL: an E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic CD4+ T cells

1 reference

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Changes in actin dynamics at the T-cell/APC interface: implications for T-cell anergy?

1 reference

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JNK is required for effector T-cell function but not for T-cell activation

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A novel E3 ubiquitin ligase substrate screen identifies Rho guanine dissociation inhibitor as a substrate of gene related to anergy in lymphocytes

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Actin cytoskeleton regulates calcium dynamics and NFAT nuclear duration

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Molecular mechanisms underlying functional T-cell unresponsiveness.

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Anergic T cells are defective in both jun NH2-terminal kinase and mitogen-activated protein kinase signaling pathways

1 reference

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LFA-1 affinity regulation is necessary for the activation and proliferation of naive T cells

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The effect of the JNK inhibitor, JIP peptide, on human T lymphocyte proliferation and cytokine production

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Upregulation of GRAIL is associated with remission of ulcerative colitis.

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WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells

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HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse

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Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction.

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The gene related to anergy in lymphocytes, an E3 ubiquitin ligase, is necessary for anergy induction in CD4 T cells

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Regulation of T cell activation and tolerance by phospholipase C gamma-1-dependent integrin avidity modulation

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JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development.

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Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

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The Role of B7 Costimulation in CD4/CD8 T Cell Homeostasis

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Defective activation of protein kinase C and Ras-ERK pathways limits IL-2 production and proliferation by CD4+CD25+ regulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19833735

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Talin1 regulates TCR-mediated LFA-1 function

1 reference

https://pubmed.ncbi.nlm.nih.gov/19833735

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Daily subcutaneous injections of peptide induce CD4+ CD25+ T regulatory cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19833735

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Immunological synapse: center of attention again

1 reference

https://pubmed.ncbi.nlm.nih.gov/19833735

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inferred from PubMed ID database lookup

Age-dependent alterations in the assembly of signal transduction complexes at the site of T cell/APC interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/19833735

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Naturally anergic and suppressive CD25(+)CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19833735

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Identifiers

10.1074/JBC.M109.024497

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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