(Q37462441)

English

Investigating the biochemical impact of DNA damage with structure-based probes: abasic sites, photodimers, alkylation adducts, and oxidative lesions

scientific article published on October 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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Europe PubMed Central

Investigating the biochemical impact of DNA damage with structure-based probes: abasic sites, photodimers, alkylation adducts, and oxidative lesions (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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author name string

Heidi A Dahlmann

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

V G Vaidyanathan

2

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Europe PubMed Central

PMC publication ID

20 August 2017

Shana J Sturla

3

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Europe PubMed Central

PMC publication ID

20 August 2017

language of work or name

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publication date

1 October 2009

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Europe PubMed Central

PMC publication ID

20 August 2017

number of pages

13

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based on heuristic

inferred from page(s)

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Europe PubMed Central

PMC publication ID

20 August 2017

48

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

40

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

9347-9359

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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Redmond Red as a redox probe for the DNA-mediated detection of abasic sites

1 reference

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DNA damage-induced cell death by apoptosis.

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Molecular mechanisms of mammalian global genome nucleotide excision repair.

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Direct reversal of DNA alkylation damage

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Incorporation of non-nucleoside triphosphate analogues opposite to an abasic site by human DNA polymerases beta and lambda.

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Oxidative damage to DNA in mammalian chromatin

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2'-deoxyribonolactone lesion produces G->A transitions in Escherichia coli

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26 June 2018

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26 June 2018

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26 June 2018

T-T cyclobutane dimers are misinstructive, rather than non-instructive, mutagenic lesions

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The substrate specificity of MutY for hyperoxidized guanine lesions in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Improved measurement of dibenzo[a,l]pyrene-induced abasic sites by the aldehyde-reactive probe assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Helicobacter pylori infection is associated with oxidatively damaged DNA in human leukocytes and decreased level of urinary 8-oxo-7,8-dihydroguanine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

The use of nonnatural nucleotides to probe the contributions of shape complementarity and pi-electron surface area during DNA polymerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

A new technique for the quantitative assessment of 8-oxoguanine in nuclear DNA as a marker of oxidative stress. Application to dystrophin-deficient DMD skeletal muscles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Simple fluorescent pyrimidine analogues detect the presence of DNA abasic sites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Voltammetric sensor for oxidized DNA using ultrathin films of osmium and ruthenium metallopolymers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Chemical properties of the leinamycin-guanine adduct in DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Direct electrochemiluminescence detection of oxidized DNA in ultrathin films containing [Os(bpy)2(PVP)10]2+.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Mutagenic effects of 2-deoxyribonolactone in Escherichia coli. An abasic lesion that disobeys the A-rule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

In vitro effects of a C4'-oxidized abasic site on DNA polymerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Evaluating the contribution of base stacking during translesion DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Detection of oxidative DNA damage in isolated marine bivalve hemocytes using the comet assay and formamidopyrimidine glycosylase (Fpg).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Determinants of unnatural nucleobase stability and polymerase recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

The hydantoin lesions formed from oxidation of 7,8-dihydro-8-oxoguanine are potent sources of replication errors in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Identification of adducts formed by pyridyloxobutylation of deoxyguanosine and DNA by 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone, a chemically activated form of tobacco specific carcinogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Base-flipping mutations of uracil DNA glycosylase: substrate rescue using a pyrene nucleotide wedge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

A minor groove binding copper-phenanthroline conjugate produces direct strand breaks via beta-elimination of 2-deoxyribonolactone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Oxidation of 7,8-dihydro-8-oxoguanine affords lesions that are potent sources of replication errors in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Repair of O(6)-methylguanine is not affected by thymine base pairing and the presence of MMR proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Characterization of hydantoin products from one-electron oxidation of 8-oxo-7,8-dihydroguanosine in a nucleoside model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Mutagenesis by O(6)-methyl-, O(6)-ethyl-, and O(6)-benzylguanine and O(4)-methylthymine in human cells: effects of O(6)-alkylguanine-DNA alkyltransferase and mismatch repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Potentiation of BCNU cytotoxicity by molecules targeting abasic lesions in DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Dynamics of translesion DNA synthesis catalyzed by the bacteriophage T4 exonuclease-deficient DNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Significance of nucleobase shape complementarity and hydrogen bonding in the formation and stability of the closed polymerase-DNA complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

8-Hydroxydeoxyguanosine and 8-hydroxyguanine as biomarkers of oxidative DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

The ability of a variety of polymerases to synthesize past site-specific cis-syn, trans-syn-II, (6-4), and Dewar photoproducts of thymidylyl-(3'-->5')-thymidine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Mutation spectra of M13 vectors containing site-specific Cis-Syn, Trans-Syn-I, (6-4), and Dewar pyrimidone photoproducts of thymidylyl-(3'-->5')-thymidine in Escherichia coli under SOS conditions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Action spectra for ultraviolet light-induced transformation of human cells to anchorage-independent growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

2 September 2018

Polycyclic Aromatic DNA-Base Surrogates: High-Affinity Binding to an Adenine-Specific Base-Flipping DNA Methyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789562

3 December 2018

The crystal structure of a hydrogen bonded complex of deoxyguanosine and 5-bromodeoxycytidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spiroiminodihydantoin Is a Major Product in the Photooxidation of 2‘-Deoxyguanosine by the Triplet States and Oxyl Radicals Generated from Hydroxyacetophenone Photolysis and Dioxetane Thermolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of the Main UV-induced Thymine Dimeric Lesions within Isolated and Cellular DNA as Measured by High Performance Liquid Chromatography-Tandem Mass Spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoselectivity, sequence specificity and mechanism of action of the azinomycin epoxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relative cytotoxicity of (6-4) photoproducts and cyclobutane dimers in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of UV-induced DNA photoproducts by 32P-postlabelling

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A synthetic nucleoside probe that discerns a DNA adduct from unmodified DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depurinating Acylfulvene−DNA Adducts: Characterizing Cellular Chemical Reactions of a Selective Antitumor Agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A potential chemotherapeutic strategy for the selective inhibition of promutagenic DNA synthesis by nonnatural nucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of spiroiminodihydantoin as a product of one-electron oxidation of 8-Oxo-7,8-dihydroguanosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermodynamic consequences of an abasic lesion in duplex DNA are strongly dependent on base sequence

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redox ribonucleosides. Isolation and characterization of 5-hydroxyuridine, 8-hydroxyguanosine, and 8-hydroxyadenosine from Torula yeast RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pH-dependent role of superoxide in riboflavin-catalyzed photooxidation of 8-oxo-7,8-dihydroguanosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative determination of cyclobutane thymine dimers in DNA by stable isotope-dilution mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and biochemical properties of cyanuric acid nucleoside-containing DNA oligomers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluating the contributions of desolvation and base-stacking during translesion DNA synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abasic site recognition in DNA as a new strategy to potentiate the action of anticancer alkylating drugs?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translesion Synthesis acrossO6-Alkylguanine DNA Adducts by Recombinant Human DNA Polymerases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete replication of plasmid DNA containing a single UV-induced lesion in human cell extracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A specific partner for abasic damage in DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reaction of apurinic/apyrimidinic sites with [14C]methoxyamine. A method for the quantitative assay of AP sites in DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylated bases in liver nucleic acids from rats treated with dimethylnitrosamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rational attempts to optimize non-natural nucleotides for selective incorporation opposite an abasic site

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of 2-deoxyribonolactone at the site of neocarzinostatin-induced cytosine release in the sequence d(AGC)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxynitrite-induced reactions of synthetic oligonucleotides containing 8-oxoguanine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural determinants for specific recognition by T4 endonuclease V

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid quantitation of ultraviolet-induced thymine-containing dimers in human cell DNA by reversed-phase high-performance liquid chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sulfolobus solfataricus DNA polymerase Dpo4 is partially inhibited by "wobble" pairing between O6-methylguanine and cytosine, but accurate bypass is preferred

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relative biological importance of cyclobutane and (6-4) pyrimidine-pyrimidone dimer photoproducts in human cells: evidence from a xeroderma pigmentosum revertant

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple and sensitive method for in vitro quantitation of abasic sites in DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian base excision repair and DNA polymerase beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coding properties of poly(deoxycytidylic acid) templates containing uracil or apyrimidinic sites: in vitro modulation of mutagenesis by deoxyribonucleic acid repair enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and damage specificity of a novel probe for the detection of abasic sites in DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757831

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI901059K

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

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