(Q37466346)

20 August 2017

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title

A mouse mammary gland involution mRNA signature identifies biological pathways potentially associated with breast cancer metastasis (English)

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20 August 2017

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2

Nathan Salomonis

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20 August 2017

Torsten Stein

1

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20 August 2017

Dimitry S A Nuyten

series ordinal

3

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20 August 2017

Marc J van de Vijver

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4

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20 August 2017

Barry A Gusterson

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5

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20 August 2017

30 April 2009

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Journal of Mammary Gland Biology and Neoplasia

20 August 2017

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20 August 2017

14

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20 August 2017

99-116

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20 August 2017

2

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https://scigraph.springernature.com/pub.10.1007/s10911-009-9120-1

20 August 2017

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Copper and genomic stability in mammals

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The tumour microenvironment as a target for chemoprevention.

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Metabolic regulation in the lactating mammary gland: a lipid synthesizing machine.

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The copper-chelating agent, trientine, suppresses tumor development and angiogenesis in the murine hepatocellular carcinoma cells.

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12 December 2020

Integrin β4 signaling promotes tumor angiogenesis

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12 December 2020

Essential role for Atox1 in the copper-mediated intracellular trafficking of the Menkes ATPase

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12 December 2020

Angiopoietin-like-4 is a potential angiogenic mediator in arthritis

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12 December 2020

The great escape: when cancer cells hijack the genes for chemotaxis and motility

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Serum trace elements and Cu/Zn ratio in breast cancer patients

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Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds

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Overexpression of hypoxia-inducible factor HIF-1alpha predicts early relapse in breast cancer: retrospective study in a series of 745 patients

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12 December 2020

Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression

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12 December 2020

Remodeling of the mammary microenvironment after lactation promotes breast tumor cell metastasis.

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12 December 2020

The metallochaperone Atox1 plays a critical role in perinatal copper homeostasis

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12 December 2020

Identifying genetic networks underlying myometrial transition to labor

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12 December 2020

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12 December 2020

Identification of human renal cell carcinoma associated genes by suppression subtractive hybridization

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12 December 2020

Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival

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12 December 2020

Copper-binding compounds as proteasome inhibitors and apoptosis inducers in human cancer

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12 December 2020

Delayed mammary gland involution in mice with mutation of the insulin-like growth factor binding protein 5 gene

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12 December 2020

Immunohistochemical Demonstration of Epidermal Growth Factor Receptor and Ceruloplasmin in Thyroid Diseases

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12 December 2020

HIF1alpha is a critical regulator of secretory differentiation and activation, but not vascular expansion, in the mouse mammary gland

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12 December 2020

Milk ceruloplasmin and its expression by mammary gland and liver in pigs

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12 December 2020

Microenvironment of the involuting mammary gland mediates mammary cancer progression

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12 December 2020

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Mammary gland involution as a multi-step process

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Multifunctional roles of insulin-like growth factor binding protein 5 in breast cancer

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Hypoxia-inducible factor-1alpha is a key regulator of metastasis in a transgenic model of cancer initiation and progression.

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12 December 2020

Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

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Claudin-3 and claudin-4 expression in ovarian epithelial cells enhances invasion and is associated with increased matrix metalloproteinase-2 activity

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12 December 2020

Inflammation and cancer

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12 December 2020

A cell proliferation signature is a marker of extremely poor outcome in a subpopulation of breast cancer patients

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12 December 2020

Cell-type-specific regulation of degradation of hypoxia-inducible factor 1 alpha: role of subcellular compartmentalization

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12 December 2020

Insulin-like growth factor binding protein-5 (IGFBP-5) induces premature cell death in the mammary glands of transgenic mice.

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12 December 2020

Repeated observation of breast tumor subtypes in independent gene expression data sets

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Concentrations of Fe, Cu and Zn in breast tissue: a synchrotron XRF study

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12 December 2020

Immunohistochemical demonstration of ceruloplasmin in follicular adenomas and thyroid carcinomas

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12 December 2020

Involution of the mouse mammary gland is associated with an immune cascade and an acute-phase response, involving LBP, CD14 and STAT3

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12 December 2020

The proteasome: a suitable antineoplastic target

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12 December 2020

IGFBP2 and IGFBP5 overexpression correlates with the lymph node metastasis in T1 breast carcinomas.

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12 December 2020

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12 December 2020

Expression of hypoxia-inducible factor (HIF-1alpha), VEGF-C and VEGF-D in non-invasive and invasive breast ductal carcinomas.

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12 December 2020

Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation.

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12 December 2020

Elevated copper and oxidative stress in cancer cells as a target for cancer treatment

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12 December 2020

The role of the ubiquitination-proteasome pathway in breast cancer: applying drugs that affect the ubiquitin-proteasome pathway to the therapy of breast cancer

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12 December 2020

Role of copper transporters in the uptake and efflux of platinum containing drugs

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12 December 2020

PANTHER version 6: protein sequence and function evolution data with expanded representation of biological pathways

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12 December 2020

Angiopoietin-like 4 prevents metastasis through inhibition of vascular permeability and tumor cell motility and invasiveness

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12 December 2020

The claudin gene family: expression in normal and neoplastic tissues

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12 December 2020

Copper lowering therapy with tetrathiomolybdate as an antiangiogenic strategy in cancer

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12 December 2020

Do inflammatory cells participate in mammary gland involution?

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12 December 2020

A new function for ceruloplasmin as an acute-phase reactant in inflammation: a scavenger of superoxide anion radicals

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12 December 2020

Inflammation and cancer: back to Virchow?

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12 December 2020

Prognostic significance of insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5 expression in breast cancer

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12 December 2020

Combination of copper-chelating agent, trientine, and methotrexate attenuates colorectal carcinoma development and angiogenesis in mice.

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12 December 2020

X-ray fluorescence and energy dispersive x-ray diffraction for the quantification of elemental concentrations in breast tissue.

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12 December 2020

Predicting a local recurrence after breast-conserving therapy by gene expression profiling

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12 December 2020

Multicenter validation of a gene expression-based prognostic signature in lymph node-negative primary breast cancer.

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12 December 2020

Developmental changes in composition of rat milk: trace elements, minerals, protein, carbohydrate and fat.

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12 December 2020

Pericellular proteases in angiogenesis and vasculogenesis

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12 December 2020

Use of ceruloplasmin levels to monitor response to therapy and predict recurrence of breast cancer.

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12 December 2020

Hepatic expression, synthesis and secretion of a novel fibrinogen/angiopoietin-related protein that prevents endothelial-cell apoptosis

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12 December 2020

An interaction between alpha-actinin and the beta 1 integrin subunit in vitro

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12 December 2020

Genes that mediate breast cancer metastasis to lung

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12 December 2020

Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis

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12 December 2020

A gene-expression signature as a predictor of survival in breast cancer

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12 December 2020

Gene expression profiling of early involuting mammary gland reveals novel genes potentially relevant to human breast cancer

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12 December 2020

Copper transport during lactation in transgenic mice expressing the human ATP7A protein

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12 December 2020

GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways

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12 December 2020

Epithelial cells remove apoptotic epithelial cells during post-lactation involution of the mouse mammary gland

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12 December 2020

Ceruloplasmin: an acute phase reactant that scavenges oxygen-derived free radicals.

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12 December 2020

Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis

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12 December 2020

Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin

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12 December 2020

Lipid synthesis in lactation: diet and the fatty acid switch

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12 December 2020

Actin-membrane interaction in focal adhesions

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12 December 2020

Regulation of ceruloplasmin in human hepatic cells by redox active copper: identification of a novel AP-1 site in the ceruloplasmin gene

1 reference

12 December 2020

The copper-chelating agent, trientine, attenuates liver enzyme-altered preneoplastic lesions in rats by angiogenesis suppression

1 reference

12 December 2020

FGF-1 and S100A13 possibly contribute to angiogenesis in endometriosis.

1 reference

12 December 2020

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

1 reference

12 December 2020

Gene expression analysis on small numbers of invasive cells collected by chemotaxis from primary mammary tumors of the mouse

1 reference

12 December 2020

Copper deficiency induced by tetrathiomolybdate suppresses tumor growth and angiogenesis.

1 reference

12 December 2020

Insulin-like growth factor binding proteins initiate cell death and extracellular matrix remodeling in the mammary gland.

1 reference

12 December 2020

Differential gene and protein expression in primary breast malignancies and their lymph node metastases as revealed by combined cDNA microarray and tissue microarray analysis

1 reference

12 December 2020

Down syndrome candidate region 1,a downstream target of VEGF, participates in endothelial cell migration and angiogenesis

1 reference

12 December 2020

Expression level of insulin-like growth factor binding protein 5 mRNA is a prognostic factor for breast cancer

1 reference

12 December 2020

10.1007/S10911-009-9120-1

Identifiers

DOI

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20 August 2017

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