(Q37466352)

20 August 2017

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title

NK and NKT cells in aging and longevity: role of zinc and metallothioneins (English)

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20 August 2017

Eugenio Mocchegiani

1

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20 August 2017

Robertina Giacconi

series ordinal

2

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20 August 2017

Catia Cipriano

series ordinal

3

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20 August 2017

Marco Malavolta

series ordinal

4

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20 August 2017

publication date

1 May 2009

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Journal of Clinical Immunology

20 August 2017

published in

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20 August 2017

volume

29

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20 August 2017

issue

4

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20 August 2017

page(s)

416-425

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https://scigraph.springernature.com/pub.10.1007/s10875-009-9298-4

20 August 2017

exact match

0 references

cites work

Age-associated augmentation of the synthetic ligand- mediated function of mouse NK1.1 ag(+) T cells: their cytokine production and hepatotoxicity in vivo and in vitro

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The +838 C/G MT2A polymorphism, metals, and the inflammatory/immune response in carotid artery stenosis in elderly people.

21 January 2018

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Zinc, immune plasticity, aging, and successful aging: role of metallothionein

21 January 2018

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Interleukin-6 regulates the zinc transporter Zip14 in liver and contributes to the hypozincemia of the acute-phase response

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NK cell activity and T-lymphocyte proliferation in healthy centenarians

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Dominant effector memory characteristics, capacity for dynamic adaptive expansion, and sex bias in the innate Valpha24 NKT cell compartment.

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Cytotoxic cells in immunodeficient athymic mice

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Immunosenescence: impact in the young as well as the old?

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Zinc improves the development of human CD34+ cell progenitors towards NK cells and increases the expression of GATA-3 transcription factor in young and old ages

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NK phenotypic markers and IL2 response in NK cells from elderly people.

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Metallothionein (I+II) confers, via c-myc, immune plasticity in oldest mice: model of partial hepatectomy/liver regeneration

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+647 A/C and +1245 MT1A polymorphisms in the susceptibility of diabetes mellitus and cardiovascular complications

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Diversity of NKR expression in aging T cells and in T cells of the aged: the new frontier into the exploration of protective immunity in the elderly.

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Zinc: mechanisms of host defense

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The immunology of exceptional individuals: the lesson of centenarians.

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Aging is associated with a rapid decline in frequency, alterations in subset composition, and enhanced Th2 response in CD1d-restricted NKT cells from human peripheral blood.

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A critical role of T-cell receptor gamma/delta cells in antibacterial protection in mice early in life

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Distribution and lytic activity of NK cell subsets in the elderly

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Later development of Fas ligand-mediated cytotoxicity as compared with granule-mediated cytotoxicity during the maturation of natural killer cells

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12 December 2020

Different rates of telomere shortening and telomerase activity reduction in CD8 T and CD16 NK lymphocytes with ageing.

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12 December 2020

Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections.

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Close phenotypic and functional similarities between human and murine alphabeta T cells expressing invariant TCR alpha-chains

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12 December 2020

Liver NKT cells: an account of heterogeneity

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12 December 2020

Zinc, T-cell pathways, aging: role of metallothioneins

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The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions

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Immunological biomarkers of ageing in man: changes in both innate and adaptive immunity are associated with health and longevity

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Zinc-bound metallothioneins and immune plasticity: lessons from very old mice and humans.

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Zinc deficiency and IL-6 -174G/C polymorphism in old people from different European countries: effect of zinc supplementation. ZINCAGE study.

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Negative modulation of human NK cell activity by purinoceptors. 2. Age-associated, gender-specific partial loss of sensitivity to ATP.

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Polymorphisms in MT1a gene coding region are associated with longevity in Italian Central female population.

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12 December 2020

Gamma/delta T lymphocytes are affected in the elderly.

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12 December 2020

CD1: antigen presentation and T cell function

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12 December 2020

Metallothionein expression in animals: a physiological perspective on function

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Correlation between zinc status and immune function in the elderly.

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Metabolic age modelling: the lesson from centenarians

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Induction of natural killer cell activity and perforin and granzyme B gene expression following continuous culture of short pulse with interleukin-12 in young and old mice

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Plasticity of neuroendocrine-thymus interactions during ontogeny and ageing: role of zinc and arginine.

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Endocytosing the death sentence

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Physiological responses of extrathymic T cells in the liver

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Distinct functional lineages of human V(alpha)24 natural killer T cells

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Exacerbated Th2-mediated airway inflammation and hyperresponsiveness in autoimmune diabetes-prone NOD mice: a critical role for CD1d-dependent NKT cells.

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12 December 2020

Neonatal invariant Valpha24+ NKT lymphocytes are activated memory cells.

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12 December 2020

Reciprocal age related change in natural killer cell receptors for MHC class I.

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12 December 2020

Functional significance of the perforin/granzyme cell death pathway

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12 December 2020

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12 December 2020

Dual mechanisms of apoptosis induction by cytotoxic lymphocytes.

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12 December 2020

Vitamin D, thyroid hormones and muscle mass influence natural killer (NK) innate immunity in healthy nonagenarians and centenarians

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12 December 2020

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12 December 2020

Major histocompatibility complex class I related molecules control the development of CD4+8- and CD4-8- subsets of natural killer 1.1+ T cell receptor-alpha/beta+ cells in the liver of mice

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12 December 2020

Metallothioneins/PARP-1/IL-6 interplay on natural killer cell activity in elderly: parallelism with nonagenarians and old infected humans. Effect of zinc supply

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12 December 2020

Age-associated impairment of murine natural killer activity

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12 December 2020

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12 December 2020

The -308G/A polymorphism of TNF-alpha influences immunological parameters in old subjects affected by infectious diseases

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12 December 2020

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12 December 2020

The regulatory role of Valpha14 NKT cells in innate and acquired immune response.

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12 December 2020

Senescence and cytokines modulate the NK cell expression

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12 December 2020

Do men and women follow different trajectories to reach extreme longevity? Italian Multicenter Study on Centenarians (IMUSCE).

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12 December 2020

NK and NK/T cells in human senescence

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12 December 2020

Zinc, metallothioneins and longevity: interrelationships with niacin and selenium

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12 December 2020

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12 December 2020

Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors

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12 December 2020

Novel -209A/G MT2A polymorphism in old patients with type 2 diabetes and atherosclerosis: relationship with inflammation (IL-6) and zinc.

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12 December 2020

The immune system in extreme longevity

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12 December 2020

Functional alteration of granulocytes, NK cells, and natural killer T cells in centenarians

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12 December 2020

Vα24+ NKT cells are decreased in elderly humans

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

The variations during the circadian cycle of liver CD1d-unrestricted NK1.1+TCR gamma/delta+ cells lead to successful ageing. Role of metallothionein/IL-6/gp130/PARP-1 interplay in very old mice

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12 December 2020

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12 December 2020

Reversibility of the thymic involution and of age-related peripheral immune dysfunctions by zinc supplementation in old mice.

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12 December 2020

Natural killer cells in the late decades of human life

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12 December 2020

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12 December 2020

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12 December 2020

Control points in NKT-cell development

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12 December 2020

Age-associated decline in IL-2 and IL-12 induction of LAK cell activity of human PBMC samples

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12 December 2020

Age-associated changes in CD8+ and CD16+ cell reactivity: clonal analysis

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12 December 2020

The -174G/C polymorphism of IL-6 is useful to screen old subjects at risk for atherosclerosis or to reach successful ageing

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12 December 2020

Chemokine production by natural killer cells from nonagenarians

1 reference

12 December 2020

Generation of human lymphokine-activated killer cells following an IL-2 pulse in elderly cancer patients

1 reference

12 December 2020

Selective requirement for c-Myc at an early stage of V(alpha)14i NKT cell development

1 reference

12 December 2020

10.1007/S10875-009-9298-4

Identifiers

DOI

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release_w6m7pdrakjetpnxfezjgqitbpq

20 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/w6m7pdrakjetpnxfezjgqitbpq

24 November 2022

mapped directly with Wikidata item

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