(Q37478061)

20 August 2017

1 reference

title

Type 17 T helper cells-origins, features and possible roles in rheumatic disease (English)

1 reference

20 August 2017

1

Francesco Annunziato

1 reference

20 August 2017

Lorenzo Cosmi

2

1 reference

20 August 2017

Francesco Liotta

series ordinal

3

1 reference

20 August 2017

Enrico Maggi

series ordinal

4

1 reference

20 August 2017

Sergio Romagnani

series ordinal

5

1 reference

20 August 2017

language of work or name

English

0 references

publication date

1 June 2009

1 reference

Nature Reviews Rheumatology

20 August 2017

1 reference

20 August 2017

5

1 reference

20 August 2017

325-331

1 reference

20 August 2017

6

1 reference

https://scigraph.springernature.com/pub.10.1038/nrrheum.2009.80

20 August 2017

0 references

cites work

Human TH1 and TH2 subsets: doubt no more

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Regulation and pro-inflammatory function of interleukin-17 family cytokines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Transforming growth factor-beta induces development of the T(H)17 lineage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Signal transduction pathways and transcriptional regulation in the control of Th17 differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

The biological functions of T helper 17 cell effector cytokines in inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Th17 cytokines and mucosal immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Development, cytokine profile and function of human interleukin 17-producing helper T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

IL-21 and TGF-beta are required for differentiation of human T(H)17 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Mutations in STAT3 and IL12RB1 impair the development of human IL-17-producing T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

TGF-beta indirectly favors the development of human Th17 cells by inhibiting Th1 cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Development of proteoglycan-induced arthritis is independent of IL-17.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Interleukin-35: odd one out or part of the family?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

After interleukin-12p40, are interleukin-23 and interleukin-17 the next therapeutic targets for inflammatory bowel disease?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Phenotypic and functional features of human Th17 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Late developmental plasticity in the T helper 17 lineage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Phenotype switching by inflammation-inducing polarized Th17 cells, but not by Th1 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

IL-17-producing human peripheral regulatory T cells retain suppressive function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Blockade of the interleukin-21/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Stat3 and Stat4 direct development of IL-17-secreting Th cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Targeting of the transcription factor STAT4 by antisense phosphorothioate oligonucleotides suppresses collagen-induced arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Polymorphisms of the IL12B and IL23R genes are associated with psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Regulation of osteoclast differentiation and function by the CaMK-CREB pathway.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Synovial membrane cytokine expression is predictive of joint damage progression in rheumatoid arthritis: a two-year prospective study (the DAMAGE study cohort).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Reduction of joint inflammation and bone erosion in rat adjuvant arthritis by treatment with interleukin-17 receptor IgG1 Fc fusion protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

IL-17/Th17 targeting: on the road to prevent chronic destructive arthritis?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Treatment with gamma-interferon triggers the onset of collagen arthritis in mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.80

Th17 cells in immunity and autoimmunity

31 March 2020

1 reference

12 December 2020

Suppression of murine collagen-induced arthritis with monoclonal anti-Ia antibodies and augmentation with IFN-gamma

1 reference

12 December 2020

Th1/Th17 cytokine profiles in patients with reactive arthritis/undifferentiated spondyloarthropathy

1 reference

12 December 2020

IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells

1 reference

12 December 2020

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2009.80

1 reference

20 August 2017

1 reference