(Q37481307)

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Involvement of PKC alpha and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of mu-opioid receptors in mature brain neurons.

scientific article published on 20 March 2009

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scholarly article

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24 January 2020

Involvement of PKC alpha and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of mu-opioid receptors in mature brain neurons (English)

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24 January 2020

G protein-coupled receptor

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desensitization

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based on heuristic

inferred from title

1

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24 January 2020

Craig A McArdle

7

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24 January 2020

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S Oldfield

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24 January 2020

J Llorente

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24 January 2020

C J Caunt

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24 January 2020

A G Teschemacher

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24 January 2020

L Roberts

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24 January 2020

F L Smith

8

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24 January 2020

W L Dewey

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24 January 2020

E Kelly

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24 January 2020

G Henderson

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24 January 2020

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20 March 2009

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24 January 2020

British Journal of Pharmacology

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24 January 2020

158

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24 January 2020

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24 January 2020

157-164

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24 January 2020

Manipulation of adenovirus vectors

1 reference

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Agonist-selective mechanisms of GPCR desensitization

1 reference

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23 August 2017

Phosphorylation-independent attenuation of GPCR signalling

1 reference

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23 August 2017

Increased response to morphine in mice lacking protein kinase C epsilon

1 reference

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23 August 2017

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

1 reference

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23 August 2017

Morphine promotes rapid, arrestin-dependent endocytosis of mu-opioid receptors in striatal neurons

1 reference

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23 August 2017

Imaging living central neurones using viral gene transfer

1 reference

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23 August 2017

PKC-alpha regulates cardiac contractility and propensity toward heart failure

1 reference

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23 August 2017

Seven-transmembrane receptors

1 reference

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23 August 2017

Opioid receptor types selectively cointernalize with G protein-coupled receptor kinases 2 and 3.

1 reference

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23 August 2017

Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin.

1 reference

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23 August 2017

Identification of PKC-isoform-specific biological actions using pharmacological approaches

1 reference

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23 August 2017

Agonist-selective endocytosis of mu opioid receptor by neurons in vivo

1 reference

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23 August 2017

A protein kinase C translocation inhibitor as an isozyme-selective antagonist of cardiac function

1 reference

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23 August 2017

Agonist-selective mechanisms of mu-opioid receptor desensitization in human embryonic kidney 293 cells

1 reference

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14 September 2017

Desensitization and internalization of metabotropic glutamate receptor 1a following activation of heterologous Gq/11-coupled receptors

1 reference

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14 September 2017

mu-Opioid receptors: Ligand-dependent activation of potassium conductance, desensitization, and internalization.

1 reference

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28 September 2017

A high-efficiency synthetic promoter that drives transgene expression selectively in noradrenergic neurons

1 reference

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28 September 2017

mu-Opioid receptor internalization: opiate drugs have differential effects on a conserved endocytic mechanism in vitro and in the mammalian brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795264

28 September 2017

G protein-coupled receptor kinase 6 (GRK6) selectively regulates endogenous secretin receptor responsiveness in NG108-15 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795264

26 June 2018

Regulation of the G protein-coupled receptor kinase GRK5 by protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795264

26 June 2018

Role of protein kinase C and mu-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795264

2 September 2018

How important is protein kinase C in mu-opioid receptor desensitization and morphine tolerance?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795264

2 September 2018

Determination of the role of conventional, novel and atypical PKC isoforms in the expression of morphine tolerance in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795264

2 September 2018

Morphine-Induced mu-opioid receptor desensitization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795264

2 September 2018

Protein kinase C activation enhances morphine-induced rapid desensitization of mu-opioid receptors in mature rat locus ceruleus neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795264

2 September 2018

Mu-opioid receptor desensitization in mature rat neurons: lack of interaction between DAMGO and morphine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795264

2 September 2018

Two distinct forms of desensitization of G-protein coupled inwardly rectifying potassium currents evoked by alkaloid and peptide mu-opioid receptor agonists

1 reference

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2 September 2018

Inhibition of spinal protein kinase Calpha expression by an antisense oligonucleotide attenuates morphine infusion-induced tolerance

1 reference

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2 September 2018

Molecular transporters for peptides: delivery of a cardioprotective epsilonPKC agonist peptide into cells and intact ischemic heart using a transport system, R(7).

1 reference

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2 September 2018

Internalization of mu-opioid receptors produced by etorphine in the rat locus coeruleus.

1 reference

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2 September 2018

Reduced development of tolerance to the analgesic effects of morphine and clonidine in PKC gamma mutant mice

1 reference

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2 September 2018

Distribution of G-protein-coupled receptor kinase (GRK) isoforms 2, 3, 5 and 6 mRNA in the rat brain

1 reference

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2 September 2018

Isozyme-specific inhibitors and activators of protein kinase C.

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Binding specificity for RACK1 resides in the V5 region of beta II protein kinase C.

1 reference

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2 September 2018

Postsynaptic signaling via the [mu]-opioid receptor: responses of dorsal horn neurons to exogenous opioids and noxious stimulation.

1 reference

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2 September 2018

A dominant negative mutant of the G protein-coupled receptor kinase 2 selectively attenuates adenosine A2 receptor desensitization.

1 reference

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2 September 2018

Differential mu opiate receptor phosphorylation and desensitization induced by agonists and phorbol esters.

1 reference

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2 September 2018

C2 Region-derived Peptides Inhibit Translocation and Function of β Protein Kinase C in Vivo

1 reference

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2 September 2018

On the potassium conductance increased by opioids in rat locus coeruleus neurones

1 reference

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2 September 2018

Identifiers

10.1111/J.1476-5381.2009.00140.X

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24 January 2020

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24 January 2020

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24 January 2020

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