(Q37481314)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19441924%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

review article

1 reference

title

Therapies for coronaviruses. Part 2: Inhibitors of intracellular life cycle (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19441924%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19441924%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

author name string

Tommy R Tong

series ordinal

1

1 reference

20 August 2017

language of work or name

English

0 references

publication date

1 April 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19441924%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Patents

28 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19441924%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19441924%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19441924%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

page(s)

415-431

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19441924%20AND%20SRC:MED&resulttype=core&format=json

Mechanisms and enzymes involved in SARS coronavirus genome expression

28 January 2020

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21 January 2018

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Synthesis, crystal structure, structure-activity relationships, and antiviral activity of a potent SARS coronavirus 3CL protease inhibitor

21 January 2018

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Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase

21 January 2018

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Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage

21 January 2018

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Identification and characterization of severe acute respiratory syndrome coronavirus replicase proteins

21 January 2018

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SARS-coronavirus replication/transcription complexes are membrane-protected and need a host factor for activity in vitro

21 January 2018

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The severe acute respiratory syndrome (SARS) coronavirus NTPase/helicase belongs to a distinct class of 5' to 3' viral helicases.

21 January 2018

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RNA interference against viruses: strike and counterstrike

21 January 2018

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Antiviral actions of interferons

21 January 2018

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21 January 2018

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APOBEC-mediated editing of viral RNA.

21 January 2018

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Mannose-binding lectin in severe acute respiratory syndrome coronavirus infection

21 January 2018

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Pathogenesis of severe acute respiratory syndrome

21 January 2018

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Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association

21 January 2018

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Evaluation of human monoclonal antibody 80R for immunoprophylaxis of severe acute respiratory syndrome by an animal study, epitope mapping, and analysis of spike variants

21 January 2018

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Inhibition of human coronavirus NL63 infection at early stages of the replication cycle

21 January 2018

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Identification of novel inhibitors of the SARS coronavirus main protease 3CLpro.

21 January 2018

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Crystal structures of the main peptidase from the SARS coronavirus inhibited by a substrate-like aza-peptide epoxide.

21 January 2018

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Screening of electrophilic compounds yields an aziridinyl peptide as new active-site directed SARS-CoV main protease inhibitor

21 January 2018

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Synthesis and evaluation of keto-glutamine analogues as potent inhibitors of severe acute respiratory syndrome 3CLpro

21 January 2018

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Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease

21 January 2018

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High-throughput screening identifies inhibitors of the SARS coronavirus main proteinase

21 January 2018

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Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats

21 January 2018

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Bats are natural reservoirs of SARS-like coronaviruses

21 January 2018

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Evaluating the 3C-like protease activity of SARS-Coronavirus: recommendations for standardized assays for drug discovery.

21 January 2018

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Three-dimensional model of a substrate-bound SARS chymotrypsin-like cysteine proteinase predicted by multiple molecular dynamics simulations: catalytic efficiency regulated by substrate binding

21 January 2018

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Dissection study on the severe acute respiratory syndrome 3C-like protease reveals the critical role of the extra domain in dimerization of the enzyme: defining the extra domain as a new target for design of highly specific protease inhibitors

21 January 2018

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Design of wide-spectrum inhibitors targeting coronavirus main proteases

21 January 2018

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Structures of Two Coronavirus Main Proteases: Implications for Substrate Binding and Antiviral Drug Design

21 January 2018

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Structure of the Main Protease from a Global Infectious Human Coronavirus, HCoV-HKU1

21 January 2018

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From genome to drug lead: identification of a small-molecule inhibitor of the SARS virus

21 January 2018

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Virtual screening of novel noncovalent inhibitors for SARS-CoV 3C-like proteinase.

21 January 2018

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Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro

21 January 2018

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Rapid identification of coronavirus replicase inhibitors using a selectable replicon RNA.

21 January 2018

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Small molecules targeting severe acute respiratory syndrome human coronavirus

21 January 2018

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Long-range cooperative interactions modulate dimerization in SARS 3CLpro.

21 January 2018

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Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme

21 January 2018

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The papain-like protease from the severe acute respiratory syndrome coronavirus is a deubiquitinating enzyme

21 January 2018

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The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity

21 January 2018

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Deubiquitination, a new function of the severe acute respiratory syndrome coronavirus papain-like protease?

21 January 2018

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Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus

21 January 2018

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Inhibition of Beta interferon induction by severe acute respiratory syndrome coronavirus suggests a two-step model for activation of interferon regulatory factor 3.

21 January 2018

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A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication

21 January 2018

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Lack of severe acute respiratory syndrome in 19 AIDS patients hospitalized together.

21 January 2018

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Consideration of highly active antiretroviral therapy in the prevention and treatment of severe acute respiratory syndrome

21 January 2018

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Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings.

21 January 2018

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Old drugs as lead compounds for a new disease? Binding analysis of SARS coronavirus main proteinase with HIV, psychotic and parasite drugs

21 January 2018

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In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds.

21 January 2018

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HIV protease inhibitor nelfinavir inhibits replication of SARS-associated coronavirus

21 January 2018

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Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV.

21 January 2018

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Screening of drugs by FRET analysis identifies inhibitors of SARS-CoV 3CL protease

21 January 2018

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Evaluation of immunomodulators, interferons and known in vitro SARS-coV inhibitors for inhibition of SARS-coV replication in BALB/c mice

21 January 2018

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Molecular model of SARS coronavirus polymerase: implications for biochemical functions and drug design

21 January 2018

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Expression, purification, and characterization of SARS coronavirus RNA polymerase.

21 January 2018

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Insights into SARS-CoV transcription and replication from the structure of the nsp7-nsp8 hexadecamer

21 January 2018

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Inhibition of severe acute respiratory syndrome-associated coronavirus (SARSCoV) by calpain inhibitors and beta-D-N4-hydroxycytidine

21 January 2018

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Metabolism and antiviral activity of ribavirin

21 January 2018

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Possible mechanisms of action and reasons for failure of antiviral therapy in chronic hepatitis C.

21 January 2018

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Inhibition of SARS coronavirus infection in vitro with clinically approved antiviral drugs

21 January 2018

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Common Adverse Events Associated with the Use of Ribavirin for Severe Acute Respiratory Syndrome in Canada

21 January 2018

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Hexamethylene amiloride blocks E protein ion channels and inhibits coronavirus replication

21 January 2018

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Amiloride derivatives block ion channel activity and enhancement of virus-like particle budding caused by HIV-1 protein Vpu.

21 January 2018

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Cation-selective ion channels formed by p7 of hepatitis C virus are blocked by hexamethylene amiloride

21 January 2018

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RNA silencing: the genome's immune system

21 January 2018

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Attenuation of SARS coronavirus by a short hairpin RNA expression plasmid targeting RNA-dependent RNA polymerase

21 January 2018

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Inhibition of genes expression of SARS coronavirus by synthetic small interfering RNAs.

21 January 2018

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Inhibition of SARS-CoV replication by siRNA.

21 January 2018

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Silencing SARS-CoV Spike protein expression in cultured cells by RNA interference

21 January 2018

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RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells

21 January 2018

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Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV).

21 January 2018

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Inhibition of SARS-associated coronavirus infection and replication by RNA interference.

21 January 2018

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Biochemical properties of phosphonoacetate and thiophosphonoacetate oligodeoxyribonucleotides

21 January 2018

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siRNA targeting the leader sequence of SARS-CoV inhibits virus replication.

21 January 2018

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Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

21 January 2018

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Pathogen recognition and innate immunity

21 January 2018

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Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists

21 January 2018

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Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane

21 January 2018

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Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain

21 January 2018

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Interferon alfacon-1 plus corticosteroids in severe acute respiratory syndrome: a preliminary study

21 January 2018

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Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou, PR China

21 January 2018

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Potent inhibition of SARS-associated coronavirus (SCOV) infection and replication by type I interferons (IFN-alpha/beta) but not by type II interferon (IFN-gamma).

21 January 2018

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Interferon-beta 1a and SARS coronavirus replication

21 January 2018

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A fatal case of Ludwig's angina and mediastinitis caused by an unusual microorganism, Gemella morbillorum

21 January 2018

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Interferon alfacon1 is an inhibitor of SARS-corona virus in cell-based models

21 January 2018

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Severe acute respiratory syndrome-related coronavirus is inhibited by interferon- alpha

21 January 2018

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Interferon alfacon 1 inhibits SARS-CoV infection in human bronchial epithelial Calu-3 cells

21 January 2018

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Pegylated interferon-alpha protects type 1 pneumocytes against SARS coronavirus infection in macaques.

21 January 2018

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Interferon-beta and interferon-gamma synergistically inhibit the replication of severe acute respiratory syndrome-associated coronavirus (SARS-CoV).

21 January 2018

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The synergistic interaction of interferon types I and II leads to marked reduction in severe acute respiratory syndrome-associated coronavirus replication and increase in the expression of mRNAs for interferon-induced proteins.

21 January 2018

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Role of interferons in the treatment of severe acute respiratory syndrome

21 January 2018

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Potential antivirals and antiviral strategies against SARS coronavirus infections

21 January 2018

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Coronaviruses and their therapy

21 January 2018

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CpG motifs in bacterial DNA trigger direct B-cell activation

21 January 2018

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Cutting edge: Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells

21 January 2018

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Anti-SARS-CoV immunity induced by a novel CpG oligodeoxynucleotide

21 January 2018

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The interferon inducer ampligen [poly(I)-poly(C12U)] markedly protects mice against coxsackie B3 virus-induced myocarditis

21 January 2018

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Interferons, Interferon Inducers, and Interferon-Ribavirin in Treatment of Flavivirus-Induced Encephalitis in Mice

21 January 2018

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Interferon alfacon-1 protects hamsters from lethal pichinde virus infection

21 January 2018

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Mismatched double-stranded RNA (polyI-polyC(12)U) is synergistic with multiple anti-HIV drugs and is active against drug-sensitive and drug-resistant HIV-1 in vitro

21 January 2018

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SARS coronavirus anti-infectives

21 January 2018

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Interferon: Ten Stories in One

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770802600698