(Q37482190)

20 August 2017

Structural and mechanistic basis behind the inhibitory interaction of PcTS on alpha-synuclein amyloid fibril formation (English)

1 reference

20 August 2017

1 reference

5

Markus Zweckstetter

0 references

author name string

Gonzalo R Lamberto

1

1 reference

20 August 2017

Andrés Binolfi

2

1 reference

20 August 2017

María L Orcellet

3

1 reference

20 August 2017

Carlos W Bertoncini

4

1 reference

20 August 2017

Markus Zweckstetter

5

1 reference

20 August 2017

Christian Griesinger

6

1 reference

20 August 2017

Claudio O Fernández

7

1 reference

20 August 2017

language of work or name

English

0 references

publication date

30 November 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

20 August 2017

1 reference

20 August 2017

106

1 reference

20 August 2017

21057-21062

1 reference

20 August 2017

50

1 reference

Structural characteristics of alpha-synuclein oligomers stabilized by the flavonoid baicalein

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

The fold of alpha-synuclein fibrils

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Protein misfolding and disease: from the test tube to the organism

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

A small-molecule therapeutic lead for Huntington's disease: preclinical pharmacology and efficacy of C2-8 in the R6/2 transgenic mouse

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Investigation of alpha-synuclein fibril structure by site-directed spin labeling

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Alpha-synuclein tertiary contact dynamics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Inhibition of amyloid fibril formation by polyphenols: structural similarity and aromatic interactions as a common inhibition mechanism

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Molecular-level secondary structure, polymorphism, and dynamics of full-length alpha-synuclein fibrils studied by solid-state NMR.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Release of long-range tertiary interactions potentiates aggregation of natively unstructured alpha-synuclein

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

A molecular model of Alzheimer amyloid beta-peptide fibril formation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Inhibition of protease-resistant prion protein formation by porphyrins and phthalocyanines

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Alpha-synuclein in Lewy bodies

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Cognitive-performance recovery of Alzheimer's disease model mice by modulation of early soluble amyloidal assemblies

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Small molecule inhibitors of alpha-synuclein filament assembly

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Phthalocyanine tetrasulfonates affect the amyloid formation and cytotoxicity of alpha-synuclein

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Tyrosine-to-cysteine modification of human alpha-synuclein enhances protein aggregation and cellular toxicity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

NMR of alpha-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Porphyrin and phthalocyanine antiscrapie compounds.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795524

Tertiary contact formation in alpha-synuclein probed by electron transfer.

26 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902603106

Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902603106

Inhibition of alpha-synuclein fibril assembly by small molecules: analysis using epitope-specific antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902603106

The flavonoid baicalein inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902603106

Characterization of alpha-synuclein interactions with selected aggregation-inhibiting small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902603106

Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902603106

Structural organization of alpha-synuclein fibrils studied by site-directed spin labeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902603106

Characterization of oligomers during alpha-synuclein aggregation using intrinsic tryptophan fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902603106

Impact of Tyr to Ala mutations on alpha-synuclein fibrillation and structural properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902603106

Characterizing bathocuproine self-association and subsequent binding to Alzheimer's disease amyloid beta-peptide by NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902603106

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19948969

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0902603106

1 reference

20 August 2017

0 references

1 reference

20 August 2017

1 reference