(Q37483117)

20 August 2017

CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets (English)

1 reference

20 August 2017

Kate S Smigiel

1

1 reference

20 August 2017

Elizabeth Richards

2

1 reference

20 August 2017

Shivani Srivastava

3

1 reference

20 August 2017

Kerri R Thomas

4

1 reference

20 August 2017

Jan C Dudda

5

1 reference

20 August 2017

Kimberly D Klonowski

6

1 reference

20 August 2017

Daniel J Campbell

7

1 reference

20 August 2017

language of work or name

English

0 references

publication date

30 December 2013

1 reference

Journal of Experimental Medicine

20 August 2017

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20 August 2017

211

1 reference

20 August 2017

1

1 reference

20 August 2017

121-136

1 reference

describes a project that uses

20 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3892972/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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IL-2-dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells

23 August 2017

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Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2.

23 August 2017

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23 August 2017

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The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology

23 August 2017

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Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo

23 August 2017

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T-bet(+) Treg cells undergo abortive Th1 cell differentiation due to impaired expression of IL-12 receptor β2

23 August 2017

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Cutting edge: IL-2 signals determine the degree of TCR signaling necessary to support regulatory T cell proliferation in vivo

23 August 2017

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CD25 blockade depletes and selectively reprograms regulatory T cells in concert with immunotherapy in cancer patients

23 August 2017

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Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency

23 August 2017

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An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes

23 August 2017

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T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse

23 August 2017

1 reference

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Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation

23 August 2017

1 reference

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Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European susceptibility loci

23 August 2017

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Foxo: in command of T lymphocyte homeostasis and tolerance

23 August 2017

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Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells

23 August 2017

1 reference

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Regulation of CD4 T cell activation and effector function by inducible costimulator (ICOS).

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Feedback control of regulatory T cell homeostasis by dendritic cells in vivo

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Human T regulatory cell therapy: take a billion or so and call me in the morning

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

IL-2 and its high-affinity receptor: genetic control of immunoregulation and autoimmunity.

23 August 2017

1 reference

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Common variants at CD40 and other loci confer risk of rheumatoid arthritis

23 August 2017

1 reference

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How regulatory T cells work

23 August 2017

1 reference

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Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

CCR7 and its ligands: balancing immunity and tolerance

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

ICOS controls the pool size of effector-memory and regulatory T cells.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

The biology of interleukin-2.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

A novel role of IL-2 in organ-specific autoimmune inflammation beyond regulatory T cell checkpoint: both IL-2 knockout and Fas mutation prolong lifespan of Scurfy mice but by different mechanisms

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Follicular shuttling of marginal zone B cells facilitates antigen transport

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Altering the distribution of Foxp3(+) regulatory T cells results in tissue-specific inflammatory disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

A key role for CCR7 in establishing central and peripheral tolerance

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

A function for interleukin 2 in Foxp3-expressing regulatory T cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Migration rules: functional properties of naive and effector/memory-like regulatory T cell subsets

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Chemoattractants and their receptors in homeostasis and inflammation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Interleukin 2 upregulates expression of its receptor on a T cell clone

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

X-linked lymphoreticular disease in the scurfy (sf) mutant mouse

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

IL-2 therapy in type 1 diabetes: "Trials" and tribulations

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Regulatory T cells in HIV infection: can immunotherapy regulate the regulator?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Differentiation and function of Foxp3(+) effector regulatory T cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

CD4(+)Foxp3(+) regulatory T cell therapy in transplantation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Clinical perspectives for regulatory T cells in transplantation tolerance

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

T-cell tolerance and the multi-functional role of IL-2R signaling in T-regulatory cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Phenotypical and functional specialization of FOXP3+ regulatory T cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Response to self antigen imprints regulatory memory in tissues

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Cutting Edge: memory regulatory t cells require IL-7 and not IL-2 for their maintenance in peripheral tissues

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

IL-2R signaling is essential for functional maturation of regulatory T cells during thymic development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

CCR7 ligands stimulate the intranodal motility of T lymphocytes in vivo

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Impaired CD4 and CD8 effector function and decreased memory T cell populations in ICOS-deficient patients

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Selective stimulation of T cell subsets with antibody-cytokine immune complexes.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Dynamics of blood-borne CD8 memory T cell migration in vivo.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Continued maturation of thymic emigrants in the periphery

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Regulation of immune and autoimmune responses by ICOS.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3892972

Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors

2 September 2018

1 reference

12 December 2020

Regulation of mouse inducible costimulator (ICOS) expression by Fyn-NFATc2 and ERK signaling in T cells

1 reference

12 December 2020

Function of the IL-2R for thymic and peripheral CD4+CD25+ Foxp3+ T regulatory cells

1 reference

12 December 2020

IL-2Rbeta links IL-2R signaling with Foxp3 expression

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20131142

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

24378538

1 reference