(Q37493746)

20 August 2017

Revisiting the SAR of the Antischistosomal Aryl Hydantoin (Ro 13-3978). (English)

1 reference

20 August 2017

13

Jennifer Keiser

1 reference

20 August 2017

3

Mireille Vargas

1 reference

20 August 2017

2

Qingjie Zhao

1 reference

20 August 2017

1

Chunkai Wang

1 reference

20 August 2017

Jeremy O Jones

4

1 reference

20 August 2017

Karen L White

5

1 reference

20 August 2017

David M Shackleford

6

1 reference

20 August 2017

Gong Chen

7

1 reference

20 August 2017

Jessica Saunders

8

1 reference

20 August 2017

Alice C F Ng

9

1 reference

20 August 2017

Francis C K Chiu

10

1 reference

20 August 2017

Yuxiang Dong

11

1 reference

20 August 2017

Susan A Charman

12

1 reference

20 August 2017

Jonathan L Vennerstrom

14

1 reference

20 August 2017

language of work or name

English

0 references

publication date

28 November 2016

1 reference

Journal of Medicinal Chemistry

20 August 2017

1 reference

20 August 2017

59

1 reference

20 August 2017

23

1 reference

20 August 2017

10705-10718

1 reference

Activity Profile of an FDA-Approved Compound Library against Schistosoma mansoni

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Aryl hydantoin Ro 13-3978, a broad-spectrum antischistosomal

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

23 August 2017

Human schistosomiasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Antischistosomal versus antiandrogenic properties of aryl hydantoin Ro 13-3978.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Schistosomiasis chemotherapy.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Pharmacology and potential physiological significance of schistosome multidrug resistance transporters

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Developments in nonsteroidal antiandrogens targeting the androgen receptor

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Activity of antiandrogens against juvenile and adult Schistosoma mansoni in mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Structure-activity relationship for thiohydantoin androgen receptor antagonists for castration-resistant prostate cancer (CRPC)

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

In vitro and in vivo trematode models for chemotherapeutic studies

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Reduced susceptibility to praziquantel among naturally occurring Kenyan isolates of Schistosoma mansoni

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Helminth infections: the great neglected tropical diseases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Cell- and gene-specific regulation of primary target genes by the androgen receptor

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Synthesis and structure-activity studies of side-chain derivatized arylhydantoins for investigation as androgen receptor radioligands

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Hormones and nuclear receptors in schistosome development

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

A high-throughput screening method for the determination of aqueous drug solubility using laser nephelometry in microtiter plates

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Pharmacological profile of RU 58642, a potent systemic antiandrogen for the treatment of androgen-dependent disorders

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

New uses for old drugs: the tale of artemisinin derivatives in the elimination of schistosomiasis japonica in China.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Schistosomiasis control: praziquantel forever?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer).

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Antimalarials in the treatment of schistosomiasis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Interactions of mefloquine with praziquantel in the Schistosoma mansoni mouse model and in vitro

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

From innovation to application: social-ecological context, diagnostics, drugs and integrated control of schistosomiasis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Study of the activity of 3-benzyl-5-(4-chloro-arylazo)-4-thioxo-imidazolidin-2-one against Schistosomiasis mansoni in mice.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Free-radical addition to ketimines generated in situ. New one-pot synthesis of quaternary alpha-aminoamides promoted by a H2O2/TiCl4-Zn/HCONH2 system

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Fast gradient HPLC method to determine compounds binding to human serum albumin. Relationships with octanol/water and immobilized artificial membrane lipophilicity.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

Polar molecular surface properties predict the intestinal absorption of drugs in humans.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5150661

A cellular conformation-based screen for androgen receptor inhibitors

3 December 2018

1 reference

12 December 2020

[Efficacy of schistosomicide derivatives, appreciation with electronic microscopy experimental model (author's transl)]

1 reference

12 December 2020

Synthesis and SAR of novel hydantoin derivatives as selective androgen receptor modulators

1 reference

12 December 2020

Determination of the dissociation constant of a weak acid using a dissolution rate method

1 reference

12 December 2020

New imidazolidinic bioisosters: potential candidates for antischistosomal drugs

1 reference

12 December 2020

10.1021/ACS.JMEDCHEM.6B01410

Identifiers

DOI

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

27933964

1 reference