(Q37494353)

English

A Phase 2, randomized, partially blinded, active-controlled study assessing the efficacy and safety of variable anticoagulation reversal using the REG1 system in patients with acute coronary syndromes: results of the RADAR trial

scientific article published on 02 August 2012

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scholarly article

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Europe PubMed Central

PMC publication ID

20 August 2017

A Phase 2, randomized, partially blinded, active-controlled study assessing the efficacy and safety of variable anticoagulation reversal using the REG1 system in patients with acute coronary syndromes: results of the RADAR trial (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

phase II clinical trial

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anticoagulation

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based on heuristic

inferred from title

acute coronary syndrome

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6

object named as

Roxana Mehran

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Mauricio G. Cohen

object named as

Mauricio G Cohen

5

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7

object named as

Christoph Bode

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Gilles Montalescot

9

object named as

Gilles Montalescot

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Jarosław Kasprzak

4

object named as

Jaroslaw D Kasprzak

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Europe PubMed Central

PMC publication ID

20 August 2017

John H. Alexander

18

object named as

John H Alexander

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Europe PubMed Central

PMC publication ID

20 August 2017

object named as

Jan H Cornel

10

1 reference

ORCID Public Data File 2021

Andrzej Rynkiewicz

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object named as

Andrzej Rynkiewicz

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Europe PubMed Central

PMC publication ID

20 August 2017

author name string

Thomas J Povsic

1

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Europe PubMed Central

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20 August 2017

John P Vavalle

2

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Europe PubMed Central

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20 August 2017

Laura H Aberle

3

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Europe PubMed Central

PMC publication ID

20 August 2017

Christopher E Buller

8

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Europe PubMed Central

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20 August 2017

Michael E Ring

12

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Europe PubMed Central

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20 August 2017

Uwe Zeymer

13

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Europe PubMed Central

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20 August 2017

Madhu Natarajan

14

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Europe PubMed Central

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20 August 2017

Nicolas Delarche

15

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Europe PubMed Central

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20 August 2017

Steven L Zelenkofske

16

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Europe PubMed Central

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20 August 2017

Richard C Becker

17

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Europe PubMed Central

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20 August 2017

RADAR Investigators

19

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Europe PubMed Central

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20 August 2017

language of work or name

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publication date

2 August 2012

1 reference

Europe PubMed Central

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20 August 2017

European Heart Journal

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

34

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Europe PubMed Central

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20 August 2017

31

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Europe PubMed Central

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20 August 2017

2481-2489

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

RUBY-1: a randomized, double-blind, placebo-controlled trial of the safety and tolerability of the novel oral factor Xa inhibitor darexaban (YM150) following acute coronary syndrome

1 reference

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23 August 2017

Bivalirudin during primary PCI in acute myocardial infarction

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23 August 2017

Uricase and other novel agents for the management of patients with treatment-failure gout

1 reference

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23 August 2017

Bivalirudin for patients with acute coronary syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3895957

23 August 2017

Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase

1 reference

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23 August 2017

Arterial puncture closing devices compared with standard manual compression after cardiac catheterization: systematic review and meta-analysis

1 reference

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23 August 2017

Vascular complications after balloon and new device angioplasty

1 reference

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23 August 2017

Translating Nucleic Acid Aptamers to Antithrombotic Drugs in Cardiovascular Medicine

1 reference

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6 September 2017

First clinical application of an actively reversible direct factor IXa inhibitor as an anticoagulation strategy in patients undergoing percutaneous coronary intervention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3895957

6 September 2017

A randomized, repeat-dose, pharmacodynamic and safety study of an antidote-controlled factor IXa inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3895957

6 September 2017

Partial factor IXa inhibition with TTP889 for prevention of venous thromboembolism: an exploratory study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3895957

6 September 2017

First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology: a phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3895957

6 September 2017

Dose selection for a direct and selective factor IXa inhibitor and its complementary reversal agent: translating pharmacokinetic and pharmacodynamic properties of the REG1 system to clinical trial design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3895957

2 September 2018

Radial versus femoral access for coronary angiography and intervention in patients with acute coronary syndromes (RIVAL): a randomised, parallel group, multicentre trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3895957

2 September 2018

Radial artery access as a predictor of increased radiation exposure during a diagnostic cardiac catheterization procedure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3895957

2 September 2018

Otamixaban for the treatment of patients with non-ST-elevation acute coronary syndromes (SEPIA-ACS1 TIMI 42): a randomised, double-blind, active-controlled, phase 2 trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3895957

2 September 2018

Impact of anticoagulation regimens on sheath management and bleeding in patients undergoing elective percutaneous coronary intervention in the STEEPLE trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3895957

2 September 2018

Phase 1b randomized study of antidote-controlled modulation of factor IXa activity in patients with stable coronary artery disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3895957

2 September 2018

Relationship between markers of activated coagulation, their correlation with inflammation, and association with coronary heart disease (NPHSII).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3895957

2 September 2018

Bleeding complications in patients with acute coronary syndrome undergoing early invasive management can be reduced with radial access, smaller sheath sizes, and timely sheath removal.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3895957

2 September 2018

Levels of intrinsic coagulation factors and the risk of myocardial infarction among men: Opposite and synergistic effects of factors XI and XII.

1 reference

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2 September 2018

Comparison of fondaparinux and enoxaparin in acute coronary syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3895957

2 September 2018

A meta-analysis of percutaneous vascular closure devices after diagnostic catheterization and percutaneous coronary intervention.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3895957

2 September 2018

Transmission of a procoagulant signal from tissue factor-bearing cell to platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/22859796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleic acid aptamers in therapeutic anticoagulation. Technology, development and clinical application

1 reference

https://pubmed.ncbi.nlm.nih.gov/22859796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of intravenous PEGylated recombinant mammalian urate oxidase in patients with refractory gout

1 reference

https://pubmed.ncbi.nlm.nih.gov/22859796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleic acid aptamers as antithrombotic agents: Opportunities in extracellular therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/22859796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Meta-analysis of randomized trials on the efficacy of vascular closure devices after diagnostic angiography and angioplasty

1 reference

https://pubmed.ncbi.nlm.nih.gov/22859796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized, partially blinded, multicenter, active-controlled, dose-ranging study assessing the safety, efficacy, and pharmacodynamics of the REG1 anticoagulation system in patients with acute coronary syndromes: design and rationale of the RADAR

1 reference

https://pubmed.ncbi.nlm.nih.gov/22859796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pegnivacogin results in near complete FIX inhibition in acute coronary syndrome patients: RADAR pharmacokinetic and pharmacodynamic substudy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22859796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/EURHEARTJ/EHS232

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

ResearchGate publication ID

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