(Q37511782)

English

Autotaxin.

scientific article published on 09 June 2009

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scholarly article

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30 January 2020

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Autotaxin (English)

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30 January 2020

1

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30 January 2020

author name string

Gilles Ferry

2

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30 January 2020

publication date

9 June 2009

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30 January 2020

Cellular and Molecular Life Sciences

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30 January 2020

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30 January 2020

18

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30 January 2020

3009-3021

1 reference

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30 January 2020

https://scigraph.springernature.com/pub.10.1007/s00018-009-0056-9

0 references

Phosphatase-resistant analogues of lysophosphatidic acid: agonists promote healing, antagonists and autotaxin inhibitors treat cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0056-9

21 January 2018

Autotaxin (ATX): a multi-functional and multi-modular protein possessing enzymatic lysoPLD activity and matricellular properties

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0056-9

21 January 2018

Lysophospholipid signaling: beyond the EDGs

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0056-9

21 January 2018

Secretion and lysophospholipase D activity of autotaxin by adipocytes are controlled by N-glycosylation and signal peptidase

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0056-9

21 January 2018

Purification and characterization of lysophospholipase D from rat brain.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0056-9

21 January 2018

Divalent cations stabilize the conformation of plasma cell membrane glycoprotein PC-1 (alkaline phosphodiesterase I).

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0056-9

21 January 2018

Lysophospholipase D and its role in LPA production

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0056-9

21 January 2018

Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0056-9

21 January 2018

Stimulatory role of lysophosphatidic acid in cyclooxygenase-2 induction by synovial fluid of patients with rheumatoid arthritis in fibroblast-like synovial cells

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0056-9

21 January 2018

Two pathways for lysophosphatidic acid production

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0056-9

21 January 2018

Autotaxin expression in non-small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0056-9

21 January 2018

Phosphodiesterase-Ialpha/autotaxin (PD-Ialpha/ATX): a multifunctional protein involved in central nervous system development and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinoic acid-induced expression of autotaxin in N-myc-amplified neuroblastoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum autotaxin measurement in haematological malignancies: a promising marker for follicular lymphoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression, regulation and function of autotaxin in thyroid carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Virtual screening approaches for the identification of non-lipid autotaxin inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional invalidation of the autotaxin gene by a single amino acid mutation in mouse is lethal

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleotide binding to autotaxin: crosslinking of bound substrate followed by lysC digestion identifies two labeled peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of autotaxin mRNA in human hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymatic activation of autotaxin by divalent cations without EF-hand loop region involvement

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LPA and its analogs-attractive tools for elucidation of LPA biology and drug development

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphodiesterase-Ialpha/autotaxin: a counteradhesive protein expressed by oligodendrocytes during onset of myelination

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression profiles of lysophosphatidic acid-related molecules in the prostate: relevance to prostate cancer and benign hyperplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of human renal cell carcinoma associated genes by suppression subtractive hybridization

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ecto-phosphodiesterase/pyrophosphatase of lymphocytes and non-lymphoid cells: structure and function of the PC-1 family

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidylcholine induces neuropathic pain through an action of autotaxin to generate lysophosphatidic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidic acids, cyclic phosphatidic acids and autotaxin as promising targets in therapies of cancer and other diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced expression of autotaxin predicts survival in uveal melanoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidic acid protection against apoptosis in the human pre-B-cell line Nalm-6.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor metastasis: mechanistic insights and clinical challenges

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteomic analysis of multiple sclerosis cerebrospinal fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidic acid (LPA) and its receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A sensitive screening assay for secreted motility-stimulating factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design and synthesis of an enzyme-cleavable sensor molecule for phosphodiesterase activity based on fluorescence resonance energy transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of the lysophosphatidic acid-generating enzyme autotaxin in lymphocyte-endothelial cell interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The candidate tumor suppressor CST6 alters the gene expression profile of human breast carcinoma cells: down-regulation of the potent mitogenic, motogenic, and angiogenic factor autotaxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic induction of tumor antigens by Wnt-1 signaling and retinoic acid revealed by gene expression profiling

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluorogenic phospholipid substrate to detect lysophospholipase D/autotaxin activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of genes associated with metastasis of mammary carcinoma in metastatic versus non-metastatic cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repeatability of published microarray gene expression analyses

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophospholipid activation of G protein-coupled receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel point mutations attenuate autotaxin activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of bioactive lysophosphatidic acid by lysophospholipase D in hen egg white

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin and lysophosphatidic acid stimulate intestinal cell motility by redistribution of the actin modifying protein villin to the developing lamellipodia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumour motility factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of a motility factor by a newly established lung adenocarcinoma cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of human melanoma cell lines according to their migratory properties in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[A study on expression of autotaxin mRNA in hepatocellular carcinoma]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning and chromosomal assignment of the human brain-type phosphodiesterase I/nucleotide pyrophosphatase gene (PDNP2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metal-ion stimulation and inhibition of lysophospholipase D which generates bioactive lysophosphatidic acid in rat plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphodiesterase I, a novel adhesion molecule and/or cytokine involved in oligodendrocyte function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible expression of a constitutively active mutant of mitogen-activated protein kinase kinase 7 specifically activates c-JUN NH2-terminal protein kinase, alters expression of at least nine genes, and inhibits cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide induces autotaxin expression in human monocytic THP-1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional characterization of the non-catalytic ectodomains of the nucleotide pyrophosphatase/phosphodiesterase NPP1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor cell autocrine motility factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The N-terminal hydrophobic sequence of autotaxin (ENPP2) functions as a signal peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin stimulates urokinase-type plasminogen activator expression through phosphoinositide 3-kinase-Akt-nuclear [corrected] factor kappa B signaling cascade in human melanoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleotide pyrophosphatases/phosphodiesterases on the move

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of tumor cell motility linked to phosphodiesterase catalytic site of autotaxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic loci that control the angiogenic response to basic fibroblast growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin, tumor motility-stimulating exophosphodiesterase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate-specifying determinants of the nucleotide pyrophosphatases/phosphodiesterases NPP1 and NPP2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of lysophosphatidic acid in blister fluid: involvement of a lysophospholipase D activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidic acid induces ovarian cancer cell dispersal by activating Fyn kinase associated with p120-catenin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular pharmacology of adipocyte-secreted autotaxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of lysophosphatidic acid in the regulation of uterine leiomyoma cell proliferation by phospholipase D and autotaxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin is an N-linked glycoprotein but the sugar moieties are not needed for its stimulation of cellular motility

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolism of lyso-platelet-activating factor (1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine) by a calcium-dependent lysophospholipase D in rabbit kidney medulla

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor and secreted targets of Wnt-1/beta-catenin signalling in mouse mammary epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hydrolysis of lysophospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site-directed mutations in the tumor-associated cytokine, autotaxin, eliminate nucleotide phosphodiesterase, lysophospholipase D, and motogenic activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diversified expression patterns of autotaxin, a gene for phospholipid-generating enzyme during mouse and chicken development.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies of lysophospholipase D of rat liver and other tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidic acid induces Ca2+ mobilization and c-Myc expression in mouse embryonic stem cells via the phospholipase C pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic phosphatidic acid is produced by autotaxin in blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

S32826, a nanomolar inhibitor of autotaxin: discovery, synthesis and applications as a pharmacological tool.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous stimulation of spinal NK1 and NMDA receptors produces LPC which undergoes ATX-mediated conversion to LPA, an initiator of neuropathic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both Plasma Lysophosphatidic Acid and Serum Autotaxin Levels are Increased in Chronic Hepatitis C

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T1/2).

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-1 beta- and IL-4-induced down-regulation of autotaxin mRNA and PC-1 in fibroblast-like synoviocytes of patients with rheumatoid arthritis (RA)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin protects MCF-7 breast cancer and MDA-MB-435 melanoma cells against Taxol-induced apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and transcriptional regulation of the PD-Ialpha/autotaxin gene in neuroblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of lysophospholipase D/autotaxin activity in human serum samples.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural characteristics of lysophosphatidic acid biological targets

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin is an exoenzyme possessing 5'-nucleotide phosphodiesterase/ATP pyrophosphatase and ATPase activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive feedback between vascular endothelial growth factor-A and autotaxin in ovarian cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peritoneal fluids from patients with certain gynecologic tumor contain elevated levels of bioactive lysophospholipase D activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphodiesterase-Ialpha/autotaxin's MORFO domain regulates oligodendroglial process network formation and focal adhesion organization

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphodiesterase-I alpha/autotaxin controls cytoskeletal organization and FAK phosphorylation during myelination.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential involvement of adipocyte insulin resistance in obesity-associated up-regulation of adipocyte lysophospholipase D/autotaxin expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is autotaxin (ENPP2) the link between hepatitis C and hepatocellular cancer?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of autotaxin as a neurite retraction-inducing factor of PC12 cells in cerebrospinal fluid and its possible sources.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental expression analysis of murine autotaxin (ATX)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation and biological activities of the autotaxin-LPA axis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidic acid signaling during embryo development in sheep: involvement in prostaglandin synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anticancer activity of FTY720: phosphorylated FTY720 inhibits autotaxin, a metastasis-enhancing and angiogenic lysophospholipase D.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of invasion and metastasis of hepatocellular carcinoma cells via targeting RhoC in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of autotaxin by the Epstein-Barr virus promotes the growth and survival of Hodgkin lymphoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning, chromosomal localization, and tissue expression of autotaxin from human teratocarcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-histidine inhibits production of lysophosphatidic acid by the tumor-associated cytokine, autotaxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation. Up-regulated expression with adipocyte differentiation and obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretion of a lysophospholipase D activity by adipocytes: involvement in lysophosphatidic acid synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scalable purification and characterization of the extracellular domain of human autotaxin from prokaryotic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of lysophosphatidic acid and lysophosphatidylcholine formation in the plasma in vitro: proposal of a plasma sample preparation method for laboratory testing of these lipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of serum and urinary lysophospholipase D/autotaxin in nephrotic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine and human autotaxin alpha, beta, and gamma isoforms: gene organization, tissue distribution, and biochemical characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A lysophospholipase D pathway in the metabolism of ether-linked lipids in brain microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microarray analysis identifies Autotaxin, a tumour cell motility and angiogenic factor with lysophospholipase D activity, as a specific target of cell transformation by v-Jun.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulated expression of the phosphodiesterase nucleotide pyrophosphatase family member PC-1 is a marker and pathogenic factor for knee meniscal cartilage matrix calcification

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic potential of autotaxin/lysophospholipase d inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrin alpha6beta4 promotes expression of autotaxin/ENPP2 autocrine motility factor in breast carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/19506801

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00018-009-0056-9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19506801%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19506801%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

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