(Q37511866)

20 August 2017

1 reference

title

Implicating the bcr/abl gene in the pathogenesis of Philadelphia chromosome-positive human leukemia (English)

1 reference

20 August 2017

0 references

1 reference

Philadelphia chromosome

1 reference

object named as

Philadelphia chromosome

2 August 2024

Daley GQ

1

1 reference

20 August 2017

Ben-Neriah Y

series ordinal

2

1 reference

20 August 2017

publication date

1 January 1991

1 reference

Advances in Cancer Research

20 August 2017

published in

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20 August 2017

volume

57

1 reference

20 August 2017

page(s)

151-184

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Oncogenic intelligence: Oncogene activation by fusion of chromosomes in leukaemia

20 August 2017

cites work

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Alterations in the p53 gene and the clonal evolution of the blast crisis of chronic myelocytic leukemia

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7 January 2021

Organization and reorganization of immunoglobulin genes in A-MuLV-transformed cells: Rearrangement of heavy but not light chain genes

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7 January 2021

bcr Rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia

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7 January 2021

Alternative 5' exons in c-abl mRNA.

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7 January 2021

The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene

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7 January 2021

Nucleic acid sequence and oncogenic properties of the HZ2 feline sarcoma virus v-abl insert

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7 January 2021

The first intron in the human c-abl gene is at least 200 kilobases long and is a target for translocations in chronic myelogenous leukemia

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7 January 2021

The Hardy–Zuckerman 2-FeSV, a new feline retrovirus with oncogene homology to Abelson-MuLV

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7 January 2021

Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton

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7 January 2021

Myristic acid is attached to the transforming protein of Rous sarcoma virus during or immediately after synthesis and is present in both soluble and membrane-bound forms of the protein

1 reference

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7 January 2021

A novel abl protein expressed in Philadelphia chromosome positive acute lymphoblastic leukaemia positive acute lymphoblastic leukaemia

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Unique forms of the abl tyrosine kinase distinguish Ph1-positive CML from Ph1-positive ALL

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Expression of a distinctive BCR-ABL oncogene in Ph1-positive acute lymphocytic leukemia (ALL).

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7 January 2021

Altered transcription of the c-abl oncogene in K-562 and other chronic myelogenous leukemia cells

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Expression of bcr and bcr-abl fusion transcripts in normal and leukemic cells

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Rapid thymomas induced by Abelson murine leukemia virus

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7 January 2021

Malignant transformation of a growth factor-dependent myeloid cell line by Abelson virus without evidence of an autocrine mechanism

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Role of phosphatidylinositol kinase in PDGF receptor signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

The CML-specific P210 bcr/abl protein, unlike v-abl, does not transform NIH/3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Activation of the c-abl oncogene by viral transduction or chromosomal translocation generates altered c-abl proteins with similar in vitro kinase properties

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Isolation of temperature-sensitive Abelson virus mutants by site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Heterogeneity of chromosome 22 breakpoint in Philadelphia-positive (Ph+) acute lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

A new fused transcript in Philadelphia chromosome positive acute lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Chronic myelocytic leukemia: Clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Chronic myelocytic leukemia. Origin of some lymphocytes from leukemic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Deletion of an N-terminal regulatory domain of the c-abl tyrosine kinase activates its oncogenic potential

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

An 8-kilobase abl RNA transcript in chronic myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Structure of the Abelson murine leukemia virus genome and the homologous cellular gene: Studies with cloned viral DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Transfection of Fibroblasts by Cloned Abelson Murine Leukemia Virus DNA and Recovery of Transmissible Virus by Recombination with Helper Virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

The human c-fps/fes gene product expressed ectopically in rat fibroblasts is nontransforming and has restrained protein-tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

The chronic myelocytic cell line K562 contains a breakpoint in bcr and produces a chimeric bcr/c-abl transcript

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

A bcr-v-abl oncogene induces lymphomas in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Chromosomal localization of human cellular homologues of two viral oncogenes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Structural organization of the bcr gene and its role in the Ph' translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

The first BCR gene intron contains breakpoints in Philadelphia chromosome positive leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Acute leukaemia in bcr/abl transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Cell lines and peripheral blood leukocytes derived from individuals with chronic myelogenous leukemia display virtually identical proteins phosphorylated on tyrosine residues

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Integrins: a family of cell surface receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Clonal and systemic analysis of long-term hematopoiesis in the mouse.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

A short amino acid sequence able to specify nuclear location

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Amino acid substitutions sufficient to convert the nontransforming p60c-src protein to a transforming protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Binding of GAP to activated PDGF receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Isolation of temperature-sensitive tyrosine kinase mutants of v-abl oncogene by screening with antibodies for phosphotyrosine

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Cell lines and clinical isolates derived from Ph1-positive chronic myelogenous leukemia patients express c-abl proteins with a common structural alteration

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Evidence that the src gene product of rous sarcoma virus is membrane associated

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

A novel human gene closely related to the abl proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

A novel c-abl protein product in Philadelphia-positive acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

The molecular genetics of Philadelphia chromosome-positive leukemias

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Nucleotide sequence of the gag gene and gag-pol junction of feline leukemia virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Transforming and membrane proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Two classes of fatty acid acylated proteins exist in eukaryotic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Chromosome Pattern of Bone Marrow Fibroblasts in Patients with Chronic Granulocytic Leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Recombinants within the tyrosine kinase region of v-abl and v-src identify a v-abl segment that confers lymphoid specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

A novel viral oncogene with structural similarity to phospholipase C

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Overlapping cDNA clones define the complete coding region for the P210c-abl gene product associated with chronic myelogenous leukemia cells containing the Philadelphia chromosome.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

PDGF induction of tyrosine phosphorylation of GTPase activating protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Friend murine leukemia virus-immortalized myeloid cells are converted into tumorigenic cell lines by Abelson leukemia virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Fine structural mapping of a critical NH2-terminal region of p60src

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Normal cellular and transformation-associated abl proteins share common sites for protein kinase C phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Neoplastic transformation of mast cells by Abelson-MuLV: abrogation of IL-3 dependence by a nonautocrine mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

In vivo tyrosine phosphorylations of the abelson virus transforming protein are absent in its normal cellular homolog

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Sequences of the A-MuLV protein needed for fibroblast and lymphoid cell transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

The minimum transforming region of v-abl is the segment encoding protein-tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Philadelphia chromosome-negative chronic myelogenous leukaemia: a morphological reassessment

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Functional macrophage cell lines transformed by abelson leukemia virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Nucleotide sequence of Abelson murine leukemia virus genome: structural similarity of its transforming gene product to other onc gene products with tyrosine-specific kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Insertional mutagenesis of the Abelson murine leukemia virus genome: identification of mutants with altered kinase activity and defective transformation ability.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Differential expression of type-specific c-abl mRNAs in mouse tissues and cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Specific and saturable binding of pp60v-src to plasma membranes: evidence for a myristyl-src receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

The viral and cellular forms of the Abelson (abl) oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Blast crisis of chronic granulocytic leukemia. Morphologic variants and therapeutic implications

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Direct transformation of 3T3 cells by Abelson murine leukaemia virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Clonal lymphoid progenitor cell lines expressing the BCR/ABL oncogene retain full differentiative function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Purification and characterization of mouse hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Evidence of a new chimeric bcr/c-abl mRNA in patients with chronic myelocytic leukemia and the Philadelphia chromosome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Evidence that the phl gene encodes a 160,000-dalton phosphoprotein with associated kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

A temperature-sensitive mutant of Abelson murine leukemia virus confers inducibility of IgM expression to transformed lymphoid cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Identification of a novel bone marrow-derived B-cell progenitor population that coexpresses B220 and Thy-1 and is highly enriched for Abelson leukemia virus targets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Cloning of bovine GAP and its interaction with oncogenic ras p21.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Novel chimaeric protein expressed in Philadelphia positive acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Cellular RNA Homologous to the Abelson Murine Leukemia Virus Transforming Gene: Expression and Relationship to the Viral Sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

The mouse c-abl locus: molecular cloning and characterization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Differentiation of cloned populations of immature B cells after transformation with abelson murine leukemia virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

A transformation-defective mutant of Abelson murine leukemia virus lacks protein kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Selective transformation of primitive lymphoid cells by the BCR/ABL oncogene expressed in long-term lymphoid or myeloid cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

Lethal effect of the abelson murine leukemia virus transforming gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960998-7

7 January 2021

10.1016/S0065-230X(08)60998-7

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