(Q37512891)

20 August 2017

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title

CNS regulation of glucose homeostasis (English)

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20 August 2017

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Carol K L Lam

1

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20 August 2017

Madhu Chari

series ordinal

2

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20 August 2017

Tony K T Lam

series ordinal

3

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20 August 2017

publication date

1 June 2009

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20 August 2017

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20 August 2017

volume

24

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20 August 2017

page(s)

159-170

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Molecular biology of adenosine triphosphate-sensitive potassium channels

20 August 2017

cites work

1 reference

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21 January 2018

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Leptin selectively decreases visceral adiposity and enhances insulin action.

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Roles for leptin receptor/STAT3-dependent and -independent signals in the regulation of glucose homeostasis

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STAT3 signalling is required for leptin regulation of energy balance but not reproduction

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Neuronal PTP1B regulates body weight, adiposity and leptin action.

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Ingestive behavior after intracerebral and intracerebroventricular infusions of glucose and 2-deoxy-D-glucose

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Selective distribution of lactate dehydrogenase isoenzymes in neurons and astrocytes of human brain

21 January 2018

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Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats.

21 January 2018

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Local lactate perfusion of the ventromedial hypothalamus suppresses hypoglycemic counterregulation

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Role of mitochondrial lactate dehydrogenase and lactate oxidation in the intracellular lactate shuttle

21 January 2018

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Role of brain insulin receptor in control of body weight and reproduction

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Critical role of STAT3 in leptin's metabolic actions

21 January 2018

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Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

21 January 2018

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Citrate diminishes hypothalamic acetyl-CoA carboxylase phosphorylation and modulates satiety signals and hepatic mechanisms involved in glucose homeostasis in rats

21 January 2018

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Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis.

21 January 2018

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Activation of central lactate metabolism lowers glucose production in uncontrolled diabetes and diet-induced insulin resistance

21 January 2018

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Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

21 January 2018

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Anatomy and regulation of the central melanocortin system

21 January 2018

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Serum immunoreactive-leptin concentrations in normal-weight and obese humans

21 January 2018

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The hypothalamic arcuate nucleus: a key site for mediating leptin's effects on glucose homeostasis and locomotor activity

21 January 2018

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Hypothalamic mTOR signaling regulates food intake

21 January 2018

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Sustained intracerebroventricular infusion of brain fuels reduces body weight and food intake in rats

21 January 2018

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Pathogenesis of type 2 diabetes mellitus

21 January 2018

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The biology of incretin hormones

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Distribution and phenotype of neurons containing the ATP-sensitive K+ channel in rat brain.

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Transgenic overexpression of leptin rescues insulin resistance and diabetes in a mouse model of lipoatrophic diabetes.

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Leptin and the regulation of body weight in mammals

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Insulin action in the brain contributes to glucose lowering during insulin treatment of diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Integration and central processing in temperature regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Attenuation of lipopolysaccharide anorexia by antagonism of caudal brain stem but not forebrain GLP-1-R.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

The sympathetic control of blood pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Weight-reducing effects of the plasma protein encoded by the obese gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Molecular disruption of hypothalamic nutrient sensing induces obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Hypothalamic malonyl-CoA as a mediator of feeding behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Role of hepatic STAT3 in brain-insulin action on hepatic glucose production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Dichloroacetate effects on glucose and lactate oxidation by neurons and astroglia in vitro and on glucose utilization by brain in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Failure of substrate-induced gluconeogenesis to increase overall glucose appearance in normal humans. Demonstration of hepatic autoregulation without a change in plasma glucose concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

The insulin resistance syndrome: physiological considerations

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Neural activity triggers neuronal oxidative metabolism followed by astrocytic glycolysis.

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

The role of depot fat in the hypothalamic control of food intake in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Hypothalamic sensing of circulating lactate regulates glucose production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Central lactate metabolism regulates food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Brain glucose metabolism controls the hepatic secretion of triglyceride-rich lipoproteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Regulation of blood glucose by hypothalamic pyruvate metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Neuronal glucosensing: what do we know after 50 years?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Nucleotides and phospholipids compete for binding to the C terminus of KATP channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Glucostatic mechanism of regulation of food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Regulation of endogenous glucose production by glucose per se is impaired in type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Feeding induced by intracerebroventricular 2-deoxy-D-glucose in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Hypothalamic responses to long-chain fatty acids are nutritionally regulated

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Leptin receptor signaling and the regulation of mammalian physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Intracellular signalling. Key enzyme in leptin-induced anorexia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Central administration of oleic acid inhibits glucose production and food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Central melanocortin receptors regulate insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Hypothalamic insulin signaling is required for inhibition of glucose production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Glucose and osmosensitive neurones of the rat hypothalamus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Endoplasmic reticulum stress plays a central role in development of leptin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Distribution of insulin receptor substrate-2 in brain areas involved in energy homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Lactate is a critical "sensed" variable in caudal hindbrain monitoring of CNS metabolic stasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Evidence supporting the existence of an activity-dependent astrocyte-neuron lactate shuttle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Effects of the obese gene product on body weight regulation in ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Hypothalamic K(ATP) channels control hepatic glucose production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Central leptin acutely reverses diet-induced hepatic insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) in high-protein diet-induced weight loss.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Hypothalamic protein kinase C regulates glucose production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Mechanism by which hyperglycemia inhibits hepatic glucose production in conscious rats. Implications for the pathophysiology of fasting hyperglycemia in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Astroglial metabolic networks sustain hippocampal synaptic transmission

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Insulin signalling and the regulation of glucose and lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Arcuate glucagon-like peptide 1 receptors regulate glucose homeostasis but not food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Central nervous system control of food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Monitoring of stored and available fuel by the CNS: implications for obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Brain IRS2 signaling coordinates life span and nutrient homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

The regulation of glucose effectiveness: how glucose modulates its own production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

A role for glucagon-like peptide-1 in the central regulation of feeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Intracerebroventricular neuropeptide Y infusion precludes inhibition of glucose and VLDL production by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Diet-induced obese mice develop peripheral, but not central, resistance to leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Localization of glucagon-like peptide (GLP) immunoreactants in human gut and pancreas using light and electron microscopic immunocytochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Regulation of blood flow in activated human brain by cytosolic NADH/NAD+ ratio

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Fatty acid synthesis and its regulation

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Control of energy homeostasis: role of enzymes and intermediates of fatty acid metabolism in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

The role of hypothalamic malonyl-CoA in energy homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Selective inactivation of Socs3 in SF1 neurons improves glucose homeostasis without affecting body weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

Positional cloning of the mouse obese gene and its human homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00003.2009

10.1152/PHYSIOL.00003.2009

21 January 2018

Identifiers

DOI

1 reference

20 August 2017

1 reference