(Q37513208)

20 August 2017

Incorporation of a single His residue by rational design enables thiol-ester hydrolysis by human glutathione transferase A1-1. (English)

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20 August 2017

1 reference

4

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20 August 2017

2

Kerstin S Broo

1 reference

20 August 2017

3

Emma Jakobsson

1 reference

20 August 2017

Sofia Hederos

1

1 reference

20 August 2017

Bengt Mannervik

series ordinal

5

1 reference

20 August 2017

Lars Baltzer

series ordinal

6

1 reference

20 August 2017

language of work or name

English

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publication date

27 August 2004

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Proceedings of the National Academy of Sciences of the United States of America

20 August 2017

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20 August 2017

101

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20 August 2017

36

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20 August 2017

13163-13167

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Enzyme-like proteins from an unselected library of designed amino acid sequences

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Programmed delivery of novel functional groups to the alpha class glutathione transferases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Catalytic proficiency: the unusual case of OMP decarboxylase

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Enzyme-like proteins by computational design

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Generation of new enzymes via covalent modification of existing proteins

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Molray--a web interface between O and the POV-Ray ray tracer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Tailoring new enzyme functions by rational redesign

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Critical analysis of antibody catalysis.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Redesign of substrate-selectivity determining modules of glutathione transferase A1-1 installs high catalytic efficiency with toxic alkenal products of lipid peroxidation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Benzoic acid derivatives induce recovery of catalytic activity in the partially inactive Met208Lys mutant of human glutathione transferase A1-1

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Rational design of a scytalone dehydratase-like enzyme using a structurally homologous protein scaffold

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Mechanism-based phage display selection of active-site mutants of human glutathione transferase A1-1 catalyzing SNAr reactions

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Selective chemical catalysis by an antibody

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Improved methods for building protein models in electron density maps and the location of errors in these models

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Engineering subtilisin and its substrates for efficient ligation of peptide bonds in aqueous solution

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Thiol ester hydrolysis catalyzed by glutathione S-transferase A1-1.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Engineering steroid 5 beta-reductase activity into rat liver 3 alpha-hydroxysteroid dehydrogenase

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516542

Conversion of a PLP-dependent racemase into an aldolase by a single active site mutation

25 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0403045101

Computational design of a biologically active enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0403045101

Role of the glutamyl alpha-carboxylate of the substrate glutathione in the catalytic mechanism of human glutathione transferase A1-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0403045101

Kinetic characterization of native and cysteine 112-modified glutathione S-transferase A1-1: reassessment of nonsubstrate ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0403045101

The C-terminal region of human glutathione transferase A1-1 affects the rate of glutathione binding and the ionization of the active-site Tyr9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0403045101

Exploration of in vitro pro-drug activation and futile cycling by glutathione S-transferases: thiol ester hydrolysis and inhibitor maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0403045101

51 Assays for differentiation of glutathione S-Transferases

21 January 2018

1 reference

12 December 2020

Engineering nitrile hydratase activity into a cysteine protease by a single mutation

1 reference

12 December 2020

Organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase: synergy results in a somanase

1 reference

12 December 2020

Interchange of catalytic activity within the 2-enoyl-coenzyme A hydratase/isomerase superfamily based on a common active site template

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0403045101

1 reference

20 August 2017

0 references

1 reference

20 August 2017

PubMed publication ID

15333749

1 reference