(Q37513318)

English

Retargeted adenoviral cancer gene therapy for tumour cells overexpressing epidermal growth factor receptor or urokinase-type plasminogen activator receptor

scientific article published on 22 April 2010

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scholarly article

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Europe PubMed Central

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31 January 2020

Retargeted adenoviral cancer gene therapy for tumour cells overexpressing epidermal growth factor receptor or urokinase-type plasminogen activator receptor (English)

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31 January 2020

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based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

cancer gene therapy

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based on heuristic

inferred from title

1

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31 January 2020

Steven D Shnyder

9

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31 January 2020

author name string

D Burdon

2

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31 January 2020

L Steele

3

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31 January 2020

N Ingram

4

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31 January 2020

G D Hall

5

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31 January 2020

R G Vile

7

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31 January 2020

P A Cooper

8

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31 January 2020

J D Chester

10

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31 January 2020

P J Selby

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31 January 2020

publication date

22 April 2010

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31 January 2020

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31 January 2020

17

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31 January 2020

8

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31 January 2020

1000-1010

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Europe PubMed Central

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31 January 2020

https://scigraph.springernature.com/pub.10.1038/gt.2010.45

0 references

In vivo retargeting of adenovirus type 5 to alphavbeta6 integrin results in reduced hepatotoxicity and improved tumor uptake following systemic delivery.

1 reference

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Targeting of adenovirus serotype 5 pseudotyped with short fiber from serotype 41 to c-erbB2-positive cells using bispecific single-chain diabody

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23 August 2017

The urokinase plasminogen activator system: a target for anti-cancer therapy.

1 reference

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23 August 2017

EGFR-targeted therapies in lung cancer: predictors of response and toxicity

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K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

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23 August 2017

Urokinase plasminogen activator receptor choreographs multiple ligand interactions: implications for tumor progression and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

23 August 2017

Growth factors and receptors as prognostic markers in urothelial carcinoma

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23 August 2017

An oncolytic adenovirus redirected with a tumor-specific T-cell receptor

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23 August 2017

The urokinase plasminogen activator receptor as a gene therapy target for cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

23 August 2017

Targeted adenovirus vectors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

23 August 2017

Transductional targeting of adenoviral cancer gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

23 August 2017

The urokinase plasminogen activator system: a rich source of tumour markers for the individualised management of patients with cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

23 August 2017

Signaling through the epidermal growth factor receptor during the development of malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

23 August 2017

Latest development in viral vectors for gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

23 August 2017

Epidermal growth factor receptor and bladder cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

23 August 2017

The mechanism of the growth-inhibitory effect of coxsackie and adenovirus receptor (CAR) on human bladder cancer: a functional analysis of car protein structure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

23 August 2017

Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

23 August 2017

Prognostic factors in renal cell and bladder cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

23 August 2017

Loss of adenoviral receptor expression in human bladder cancer cells: a potential impact on the efficacy of gene therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

23 August 2017

Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

23 August 2017

Interactions of soluble recombinant integrin alphav beta5 with human adenoviruses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

6 September 2017

Virotherapy of ovarian cancer with polymer-cloaked adenovirus retargeted to the epidermal growth factor receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

14 September 2017

Targeting EGFR in bladder cancer

1 reference

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14 September 2017

Targeting the CYP2B 1/cyclophosphamide suicide system to fibroblast growth factor receptors results in a potent antitumoral response in pancreatic cancer models

1 reference

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14 September 2017

In vivo analysis of a genetically modified adenoviral vector targeted to human CD40 using a novel transient transgenic model.

1 reference

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Complex mosaicism is a novel approach to infectivity enhancement of adenovirus type 5-based vectors.

1 reference

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Noninvasive of adenovirus tumor retargeting in living subjects by a soluble adenovirus receptor-epidermal growth factor (sCAR-EGF) fusion protein

1 reference

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Transport across a polarized monolayer of Caco-2 cells by transferrin receptor-mediated adenovirus transcytosis

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Genetically targeted adenovirus vector directed to CD40-expressing cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

14 September 2017

The urokinase-type plasminogen activator system in cancer metastasis: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

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Adenovirus type 5 fiber knob binds to MHC class I alpha2 domain at the surface of human epithelial and B lymphoblastoid cells

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Retargeting of human T cells to tumor-associated MUC1: the evolution of a chimeric antigen receptor

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Adenovirus serotype 5 hexon mediates liver gene transfer

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Retargeting of adenoviral infection to melanoma: Combining genetic ablation of native tropism with a recombinant bispecific single‐chain diabody (scDb) adapter that binds to fiber knob and HMWMAA

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Targeting of adenovirus to human renal cell carcinoma cells

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CD40 is expressed on ovarian cancer cells and can be utilized for targeting adenoviruses.

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Adenovirus-mediated gene therapy for bladder cancer: efficient gene delivery to normal and malignant human urothelial cells in vitro and ex vivo

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Integrin alpha(v) and coxsackie adenovirus receptor expression in clinical bladder cancer

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The therapeutic efficacy of adenoviral vectors for cancer gene therapy is limited by a low level of primary adenovirus receptors on tumour cells

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Adenoviral gene therapy for renal cancer requires retargeting to alternative cellular receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901412

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Overexpression of epidermal growth factor receptor in urothelium elicits urothelial hyperplasia and promotes bladder tumor growth.

1 reference

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Epidermal growth factor receptor targeting of replication competent adenovirus enhances cytotoxicity in bladder cancer

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Gene transfer to ovarian cancer versus normal tissues with fiber-modified adenoviruses

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Enhancement of the adenoviral sensitivity of human ovarian cancer cells by transient expression of coxsackievirus and adenovirus receptor (CAR).

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Improved gene transfer efficiency to primary and established human pancreatic carcinoma target cells via epidermal growth factor receptor and integrin-targeted adenoviral vectors

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Expression of UPA and UPAR is associated with the clinical course of urinary bladder neoplasms

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Plasminogen- and colony-stimulating factor-1-associated markers in bladder carcinoma: diagnostic value of urokinase plasminogen activator receptor and plasminogen activator inhibitor type-2 using immunocytochemical analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410926

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based on heuristic

inferred from PubMed ID database lookup

Association of plasma urokinase-type plasminogen activator and its receptor with clinical outcome in patients undergoing radical cystectomy for transitional cell carcinoma of the bladder

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410926

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based on heuristic

inferred from PubMed ID database lookup

UKCCCR guidelines for the welfare of animals in experimental neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/GT.2010.45

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20410926%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

PMC publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20410926%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20410926%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

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