(Q37516599)

20 August 2017

2 references

11 September 2020

24 December 2022

Bench-to-bedside review: Appropriate antibiotic therapy in severe sepsis and septic shock--does the dose matter? (English)

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20 August 2017

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11 September 2020

5 references

22 June 2019

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24 December 2022

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9 August 2020

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2

Pierluigi Viale

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20 August 2017

Federico Pea

1

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20 August 2017

language of work or name

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10 June 2009

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20 August 2017

23 March 2019

22 June 2019

4 August 2019

9 August 2020

11 September 2020

24 December 2022

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20 August 2017

23 March 2019

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4 August 2019

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11 September 2020

24 December 2022

13

1 reference

20 August 2017

3

1 reference

20 August 2017

214

1 reference

https://scigraph.springernature.com/pub.10.1186/cc7774

20 August 2017

0 references

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23 August 2017

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23 August 2017

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Application of basic pharmacokinetic concepts to analysis of microdialysis data: illustration with imipenem muscle distribution

23 August 2017

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23 August 2017

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Comparison of clinical cure rates in adults with ventilator-associated pneumonia treated with intravenous ceftazidime administered by continuous or intermittent infusion: a retrospective, nonrandomized, open-label, historical chart review

23 August 2017

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23 August 2017

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Pharmacokinetic considerations for antimicrobial therapy in patients receiving renal replacement therapy

23 August 2017

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23 August 2017

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Population pharmacokinetics and pharmacodynamics of continuous versus short-term infusion of imipenem-cilastatin in critically ill patients in a randomized, controlled trial

23 August 2017

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The antimicrobial therapy puzzle: could pharmacokinetic-pharmacodynamic relationships be helpful in addressing the issue of appropriate pneumonia treatment in critically ill patients?

23 August 2017

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Use of broad-spectrum antimicrobials for the treatment of pneumonia in seriously ill patients: maximizing clinical outcomes and minimizing selection of resistant organisms

23 August 2017

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Antimicrobial therapy in critically ill patients: a review of pathophysiological conditions responsible for altered disposition and pharmacokinetic variability

23 August 2017

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Continuous versus intermittent intravenous administration of antibiotics: a meta-analysis of randomised controlled trials

23 August 2017

1 reference

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Ceftazidime in acute myeloid leukemia patients with febrile neutropenia: helpfulness of continuous intravenous infusion in maximizing pharmacodynamic exposure

23 August 2017

1 reference

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Antimicrobial treatment of lower respiratory tract infections in the hospital setting

23 August 2017

1 reference

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Guidelines for the Management of Adults with Hospital-acquired, Ventilator-associated, and Healthcare-associated Pneumonia

23 August 2017

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Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'.

23 August 2017

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Vancomycin penetration of uninfected pleural fluid exudate after continuous or intermittent infusion

23 August 2017

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Comparative stability studies of antipseudomonal beta-lactams for potential administration through portable elastomeric pumps (home therapy for cystic fibrosis patients) and motor-operated syringes (intensive care units)

23 August 2017

1 reference

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Pharmacokinetic aspects of treating infections in the intensive care unit: focus on drug interactions

23 August 2017

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Pharmacokinetic profiles of high-dose intravenous ciprofloxacin in severe sepsis. The Baragwanath Ciprofloxacin Study Group

23 August 2017

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Levofloxacin population pharmacokinetics and creation of a demographic model for prediction of individual drug clearance in patients with serious community-acquired infection.

23 August 2017

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Continuous versus intermittent administration of ceftazidime in experimental Klebsiella pneumoniae pneumonia in normal and leukopenic rats

23 August 2017

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Prediction of creatinine clearance from serum creatinine

23 August 2017

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Levofloxacin 750-mg for 5 days for the treatment of hospitalized Fine Risk Class III/IV community-acquired pneumonia patients.

23 August 2017

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A simple formula for individualising ceftazidime dosage administered by continuous infusion in patients with haematological malignancies.

14 September 2017

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Pharmacokinetics and pharmacodynamics of meropenem in febrile neutropenic patients with bacteremia

14 September 2017

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Teicoplanin in patients with acute leukaemia and febrile neutropenia: a special population benefiting from higher dosages

14 September 2017

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TDM coupled with Bayesian forecasting should be considered an invaluable tool for optimizing vancomycin daily exposure in unstable critically ill patients

14 September 2017

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Pharmacodynamic evaluation of extending the administration time of meropenem using a Monte Carlo simulation

14 September 2017

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Impact of altered aminoglycoside volume of distribution on the adequacy of a three milligram per kilogram loading dose. Critical Care Research Group

28 September 2017

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The epidemic of antibiotic-resistant infections: a call to action for the medical community from the Infectious Diseases Society of America

28 September 2017

1 reference

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Ciprofloxacin use in critically ill patients: pharmacokinetic and pharmacodynamic approaches

28 September 2017

1 reference

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Simultaneous central nervous system distribution and pharmacokinetic-pharmacodynamic modelling of the electroencephalogram effect of norfloxacin administered at a convulsant dose in rats.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Nonconvulsive status epilepticus associated with cephalosporins in patients with renal failure.

25 June 2018

1 reference

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Single or multiple daily doses of aminoglycosides: a meta-analysis

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Is antimicrobial underexposure due to glomerular hyperfiltration a possible cause of increased mortality rate from bacterial infections in critically ill patients?

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Population pharmacokinetics of high-dose, prolonged-infusion cefepime in adult critically ill patients with ventilator-associated pneumonia

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Plasma and peritoneal concentration following continuous infusion of cefotaxime in patients with secondary peritonitis

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Clinical cure of ventilator-associated pneumonia treated with piperacillin/tazobactam administered by continuous or intermittent infusion

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Glomerular hyperfiltration and albuminuria in critically ill patients

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Alveolar concentrations of piperacillin/tazobactam administered in continuous infusion to patients with ventilator-associated pneumonia

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Should the currently recommended twice-daily dosing still be considered the most appropriate regimen for treating MRSA ventilator-associated pneumonia with vancomycin?

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Outcomes of bacteremia due to Pseudomonas aeruginosa with reduced susceptibility to piperacillin-tazobactam: implications on the appropriateness of the resistance breakpoint

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

The neurotoxicity and safety of treatment with cefepime in patients with renal failure

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Effect of severity of sepsis on tissue concentrations of linezolid

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Optimal dosing of piperacillin-tazobactam for the treatment of Pseudomonas aeruginosa infections: prolonged or continuous infusion?

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Variability in teicoplanin protein binding and its prediction using serum albumin concentrations.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Replacement of 24-h creatinine clearance by 2-h creatinine clearance in intensive care unit patients: a single-center study.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Pharmacodynamic target attainment of six beta-lactams and two fluoroquinolones against Pseudomonas aeruginosa, Acinetobacter baumannii, Escherichia coli, and Klebsiella species collected from United States intensive care units in 2004.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Meropenem by continuous versus intermittent infusion in ventilator-associated pneumonia due to gram-negative bacilli

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Pneumonia caused by oxacillin-resistant Staphylococcus aureus treated with glycopeptides

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Inhibition of daptomycin by pulmonary surfactant: in vitro modeling and clinical impact

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Assessment of renal function in recently admitted critically ill patients with normal serum creatinine

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Pharmacokinetics and intrapulmonary diffusion of levofloxacin in critically ill patients with severe community-acquired pneumonia

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Effect of once-daily dosing vs. multiple daily dosing of tobramycin on enzyme markers of nephrotoxicity

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Imipenem levels are not predictable in the critically ill patient

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Steady-state plasma and intrapulmonary concentrations of cefepime administered in continuous infusion in critically ill patients with severe nosocomial pneumonia

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Pharmacokinetics and pharmacodynamics of sequential intravenous and subcutaneous teicoplanin in critically ill patients without vasopressors

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Pharmacokinetics and pharmacodynamics of intravenous levofloxacin in patients with early-onset ventilator-associated pneumonia

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Teicoplanin therapeutic drug monitoring in critically ill patients: a retrospective study emphasizing the importance of a loading dose

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Experience with a once-daily dosing program of aminoglycosides in critically ill patients

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Cefepime-induced neurotoxicity: an underestimated complication of antibiotherapy in patients with acute renal failure

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

Impaired target site penetration of beta-lactams may account for therapeutic failure in patients with septic shock

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717408

The effect of multifactorial, multidisciplinary educational interventions on appropriate use of teicoplanin

2 September 2018

1 reference

12 December 2020

Steady-state trough serum and epithelial lining fluid concentrations of teicoplanin 12 mg/kg per day in patients with ventilator-associated pneumonia

1 reference

12 December 2020

Which reliable pharmacodynamic breakpoint should be advised for ciprofloxacin monotherapy in the hospital setting? A TDM-based retrospective perspective

1 reference

12 December 2020

Increased amikacin dosage requirements in burn patients receiving a once-daily regimen

1 reference

12 December 2020

Once-daily tobramycin in cystic fibrosis: better for clinical outcome than thrice-daily tobramycin but more resistance development?

1 reference

12 December 2020

Influence of renal function on trough serum concentrations of piperacillin in intensive care unit patients

1 reference

12 December 2020

Piperacillin-tazobactam for Pseudomonas aeruginosa infection: clinical implications of an extended-infusion dosing strategy

1 reference

12 December 2020

Pharmacokinetics of Meropenem Determined by Microdialysis in the Peritoneal Fluid of Patients With Severe Peritonitis Associated With Septic Shock

1 reference

12 December 2020

Inadequate treatment of ventilator-associated pneumonia: risk factors and impact on outcomes

1 reference

12 December 2020

Antimicrobial therapy escalation and hospital mortality among patients with health-care-associated pneumonia: a single-center experience

1 reference

12 December 2020

Stability of vancomycin in plastic syringes measured by high-performance liquid chromatography

1 reference

12 December 2020

Drug equilibration across the blood-brain barrier--pharmacokinetic considerations based on the microdialysis method

1 reference

12 December 2020

Population pharmacokinetics of amikacin in patients with haematological malignancies

1 reference

12 December 2020

Relationship between minimum inhibitory concentration and stationary concentration revisited: growth rates and minimum bactericidal concentrations

1 reference

12 December 2020

Identifiers

DOI

10.1186/CC7774

1 reference

Dimensions Publication ID

20 August 2017

0 references

1 reference

20 August 2017

PubMed publication ID

19519961

1 reference