(Q37521086)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19530987%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

review article

1 reference

title

Dickkopf-1: a suitable target for the management of myeloma bone disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19530987%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

author

Athanasios Dimopoulos

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19530987%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

author name string

Maria Gavriatopoulou

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19530987%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Dimitrios Christoulas

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19530987%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Magdalini Migkou

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19530987%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Marina Iakovaki

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19530987%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Maria Gkotzamanidou

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19530987%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Evangelos Terpos

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19530987%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

language of work or name

English

0 references

publication date

1 July 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19530987%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Targets

31 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19530987%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19530987%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19530987%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

page(s)

839-848

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19530987%20AND%20SRC:MED&resulttype=core&format=json

Novel aspects of osteoclast activation and osteoblast inhibition in myeloma bone disease

31 January 2020

cites work

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Myeloma bone disease: pathophysiology and management.

21 January 2018

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RANK ligand and osteoprotegerin in myeloma bone disease.

21 January 2018

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Pathophysiology of multiple myeloma bone disease

21 January 2018

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Production of Wnt inhibitors by myeloma cells: potential effects on canonical Wnt pathway in the bone microenvironment.

21 January 2018

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Multiple myeloma bone disease: Pathophysiology of osteoblast inhibition.

21 January 2018

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Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myeloma

21 January 2018

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The role of Dickkopf-1 in bone development, homeostasis, and disease

21 January 2018

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Wnt signaling in osteoblasts and bone diseases

21 January 2018

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Wnt/beta-catenin signaling in development and disease

21 January 2018

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DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway

21 January 2018

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Wnt signaling: a win for bone

21 January 2018

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Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

21 January 2018

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Secreted antagonists of the Wnt signalling pathway

21 January 2018

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Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

21 January 2018

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Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity

21 January 2018

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The Wnt signaling pathway in development and disease

21 January 2018

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21 January 2018

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A mechanism for Wnt coreceptor activation

21 January 2018

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21 January 2018

1 reference

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Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors

21 January 2018

1 reference

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Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow

21 January 2018

1 reference

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Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling

21 January 2018

1 reference

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Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling

21 January 2018

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Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning

21 January 2018

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21 January 2018

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The Frizzled family: receptors for multiple signal transduction pathways

21 January 2018

1 reference

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Attenuation of WNT signaling by DKK-1 and -2 regulates BMP2-induced osteoblast differentiation and expression of OPG, RANKL and M-CSF

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Analysis of endogenous LRP6 function reveals a novel feedback mechanism by which Wnt negatively regulates its receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Wnt expression and canonical Wnt signaling in human bone marrow B lymphopoiesis

21 January 2018

1 reference

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Wnt proteins are lipid-modified and can act as stem cell growth factors

21 January 2018

1 reference

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Functional and structural diversity of the human Dickkopf gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling

21 January 2018

1 reference

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Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

An LDL-receptor-related protein mediates Wnt signalling in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Osteoimmunology: interactions of the bone and immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Bone resorption by osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Soluble receptor activator of nuclear factor kappaB ligand-osteoprotegerin ratio predicts survival in multiple myeloma: proposal for a novel prognostic index

21 January 2018

1 reference

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High bone density due to a mutation in LDL-receptor-related protein 5

21 January 2018

1 reference

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A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait

21 January 2018

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Bone mass is inversely proportional to Dkk1 levels in mice

21 January 2018

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WNT signalling and haematopoiesis: a WNT-WNT situation

21 January 2018

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Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia

21 January 2018

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Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma

21 January 2018

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The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma

21 January 2018

1 reference

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Serum concentrations of DKK-1 correlate with the extent of bone disease in patients with multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo

21 January 2018

1 reference

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The combination of bortezomib, melphalan, dexamethasone and intermittent thalidomide is an effective regimen for relapsed/refractory myeloma and is associated with improvement of abnormal bone metabolism and angiogenesis

21 January 2018

1 reference

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Bone lesions in molecular subtypes of multiple myeloma.

21 January 2018

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Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone

21 January 2018

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Glucocorticoid enhances the expression of dickkopf-1 in human osteoblasts: novel mechanism of glucocorticoid-induced osteoporosis

21 January 2018

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Myeloma bone disease and proteasome inhibition therapies.

21 January 2018

1 reference

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Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Stimulation of new bone formation by the proteasome inhibitor, bortezomib: implications for myeloma bone disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Response to bortezomib is associated to osteoblastic activation in patients with multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Bortezomib induces osteoblast differentiation via Wnt-independent activation of beta-catenin/TCF signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

The oxidative stress response regulates DKK1 expression through the JNK signaling cascade in multiple myeloma plasma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Autologous stem cell transplantation normalizes abnormal bone remodeling and sRANKL/osteoprotegerin ratio in patients with multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

A crosstalk between myeloma cells and marrow stromal cells stimulates production of DKK1 and interleukin-6: a potential role in the development of lytic bone disease and tumor progression in multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Inhibiting Dickkopf-1 (Dkk1) removes suppression of bone formation and prevents the development of osteolytic bone disease in multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Illegitimate WNT signaling promotes proliferation of multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Wnt signaling in B-cell neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Serum concentrations of Dickkopf-1 protein are increased in patients with multiple myeloma and reduced after autologous stem cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

Bortezomib reduces serum dickkopf-1 and receptor activator of nuclear factor-?B ligand concentrations and normalises indices of bone remodelling in patients with relapsed multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903025770

10.1517/14728220903025770

21 January 2018

Identifiers

DOI

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ll4bi2cq4zdypf2gyjve4oh6pq

mapped directly with Wikidata item

30 July 2022

based on heuristic

Fatcat ID

release_ll4bi2cq4zdypf2gyjve4oh6pq

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ll4bi2cq4zdypf2gyjve4oh6pq

mapped directly with Wikidata item

30 July 2022

based on heuristic

1 reference

https://api.fatcat.wiki/v0/release/ll4bi2cq4zdypf2gyjve4oh6pq