(Q37525231)

20 August 2017

Hypoxia increases gefitinib-resistant lung cancer stem cells through the activation of insulin-like growth factor 1 receptor (English)

1 reference

20 August 2017

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neoplastic stem cells

1 reference

1 reference

3

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3 June 2020

Muneaki Hashimoto

6

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3 June 2020

author name string

Akiko Murakami

1

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3 June 2020

Fumiyuki Takahashi

2

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3 June 2020

Isao Kobayashi

4

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3 June 2020

Kunihiko Minakata

5

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3 June 2020

Takeshi Nara

7

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3 June 2020

Motoyasu Kato

8

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3 June 2020

Ken Tajima

9

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3 June 2020

Naoko Shimada

10

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3 June 2020

Shin-ichiro Iwakami

11

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3 June 2020

Mariko Moriyama

12

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3 June 2020

Hiroyuki Moriyama

13

1 reference

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3 June 2020

Fumiaki Koizumi

14

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3 June 2020

Kazuhisa Takahashi

15

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3 June 2020

language of work or name

English

0 references

publication date

28 January 2014

1 reference

20 August 2017

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3 June 2020

volume

9

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3 June 2020

issue

1

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3 June 2020

page(s)

e86459

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Creative Commons Attribution 4.0 International

3 June 2020

copyright license

start time

28 January 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition

23 August 2017

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23 August 2017

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Activation of the insulin-like growth factor-1 receptor induces resistance to epidermal growth factor receptor antagonism in head and neck squamous carcinoma cells

23 August 2017

1 reference

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23 August 2017

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23 August 2017

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Impact of the hypoxic tumor microenvironment on the regulation of cancer stem cell characteristics

23 August 2017

1 reference

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Lung cancer stem cells: tools and targets to fight lung cancer.

23 August 2017

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A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

23 August 2017

1 reference

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Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway.

23 August 2017

1 reference

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Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancers dependent on the epidermal growth factor receptor pathway.

23 August 2017

1 reference

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The increasing complexity of the cancer stem cell paradigm

23 August 2017

1 reference

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Cancer stem cells, hypoxia and metastasis

23 August 2017

1 reference

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Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition

23 August 2017

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Insulin and insulin-like growth factor signalling in neoplasia

23 August 2017

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Oct-4 expression maintained cancer stem-like properties in lung cancer-derived CD133-positive cells

23 August 2017

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Increased prevalence of EGFR-mutant lung cancer in women and in East Asian populations: analysis of estrogen-related polymorphisms

23 August 2017

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Resistance mechanisms to cancer chemotherapy

23 August 2017

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The epithelial-mesenchymal transition generates cells with properties of stem cells

23 August 2017

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Mechanisms of Disease: cancer stem cells--targeting the evil twin

23 August 2017

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Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming

23 August 2017

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Identification and expansion of the tumorigenic lung cancer stem cell population

23 August 2017

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Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer

23 August 2017

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Pooled analysis of the prospective trials of gefitinib monotherapy for EGFR-mutant non-small cell lung cancers

23 August 2017

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Hypoxia-inducible factors, stem cells, and cancer

23 August 2017

1 reference

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MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

23 August 2017

1 reference

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Epidermal growth factor receptor mutations in lung cancer

23 August 2017

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23 August 2017

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Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells.

23 August 2017

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ALDH-positive lung cancer stem cells confer resistance to epidermal growth factor receptor tyrosine kinase inhibitors

6 September 2017

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Hypoxia induces gefitinib resistance in non-small-cell lung cancer with both mutant and wild-type epidermal growth factor receptors.

6 September 2017

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Upregulation of CXCR4 is functionally crucial for maintenance of stemness in drug-resistant non-small cell lung cancer cells

6 September 2017

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Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells

6 September 2017

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Reciprocal and complementary role of MET amplification and EGFR T790M mutation in acquired resistance to kinase inhibitors in lung cancer

14 September 2017

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Phase II study of the anti-insulin-like growth factor type 1 receptor antibody CP-751,871 in combination with paclitaxel and carboplatin in previously untreated, locally advanced, or metastatic non-small-cell lung cancer.

2 September 2018

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10.1371/JOURNAL.PONE.0086459

2 September 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24489728%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24489728%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

PubMed publication ID

24489728

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24489728%20AND%20SRC:MED&resulttype=core&format=json