(Q37527357)

20 August 2017

PTEN opposes negative selection and enables oncogenic transformation of pre-B cells (English)

1 reference

20 August 2017

17

Markus Müschen

0 references

Thomas Graeber

object named as

Thomas G Graeber

14

0 references

Andreas Hochhaus

object named as

Andreas Hochhaus

10

0 references

author name string

Seyedmehdi Shojaee

1

1 reference

20 August 2017

Lai N Chan

2

1 reference

20 August 2017

Maike Buchner

3

1 reference

20 August 2017

Valeria Cazzaniga

4

1 reference

20 August 2017

Kadriye Nehir Cosgun

5

1 reference

20 August 2017

Huimin Geng

6

1 reference

20 August 2017

Yi Hua Qiu

7

1 reference

20 August 2017

Marcus Dühren von Minden

8

1 reference

20 August 2017

Thomas Ernst

9

1 reference

20 August 2017

Giovanni Cazzaniga

11

1 reference

20 August 2017

Ari Melnick

12

1 reference

20 August 2017

Steven M Kornblau

13

1 reference

20 August 2017

Hong Wu

15

1 reference

20 August 2017

Hassan Jumaa

16

1 reference

20 August 2017

Markus Müschen

17

1 reference

20 August 2017

language of work or name

English

0 references

publication date

14 March 2016

1 reference

20 August 2017

1 reference

20 August 2017

22

1 reference

20 August 2017

4

1 reference

20 August 2017

379-387

1 reference

Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

A human immunodeficiency caused by mutations in the PIK3R1 gene

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Pten loss in the bone marrow leads to G-CSF-mediated HSC mobilization

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Activation of a metabolic gene regulatory network downstream of mTOR complex 1

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

PTEN is a tumor suppressor in CML stem cells and BCR-ABL-induced leukemias in mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Lack of CpG island methylator phenotype defines a clinical subtype of T-cell acute lymphoblastic leukemia associated with good prognosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Stepwise reprogramming of B cells into macrophages

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

A census of human cancer genes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Predominant autoantibody production by early human B cell precursors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Proliferation kinetics and the lifespan of B cells in central and peripheral lymphoid organs

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Autoreactive B cell receptors mimic autonomous pre-B cell receptor signaling and induce proliferation of early B cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

A small molecule inhibitor for phosphatase and tensin homologue deleted on chromosome 10 (PTEN).

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

PI3 kinase signals BCR-dependent mature B cell survival

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Regulation of B-cell development by BCAP and CD19 through their binding to phosphoinositide 3-kinase

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5178869

2 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM.4062

Pretreatment with phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.4062

Comparative isoschizomer profiling of cytosine methylation: the HELP assay

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.4062

Censoring of autoreactive B cell development by the pre-B cell receptor

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26974310

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NM.4062

1 reference

release_4a4t3dknrfe7nbz6nj2ewwm62e

20 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4a4t3dknrfe7nbz6nj2ewwm62e

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

20 August 2017

PubMed publication ID

26974310

1 reference