(Q37528847)

20 August 2017

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title

Retinoblastoma protein: a central processing unit (English)

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20 August 2017

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Poznic M

1

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20 August 2017

publication date

1 June 2009

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20 August 2017

published in

Journal of Biosciences

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20 August 2017

volume

34

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20 August 2017

issue

2

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20 August 2017

page(s)

305-312

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https://scigraph.springernature.com/pub.10.1007/s12038-009-0034-2

20 August 2017

exact match

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cites work

Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene

1 reference

https://api.crossref.org/works/10.1007%2FS12038-009-0034-2

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12038-009-0034-2

Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12038-009-0034-2

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12038-009-0034-2

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12038-009-0034-2

Regulation of gene transcription by the histone H2A N-terminal domain

21 January 2018

1 reference

12 December 2020

A Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cells

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12 December 2020

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

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12 December 2020

Site-specific and temporally-regulated retinoblastoma protein dephosphorylation by protein phosphatase type 1.

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12 December 2020

Caspase 3 deficiency rescues peripheral nervous system defect in retinoblastoma nullizygous mice

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12 December 2020

GABP, HCF-1 and YY1 are involved in Rb gene expression during myogenesis

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12 December 2020

Loss of heterozygosity of the Rb gene correlates with pRb protein expression and associates with p53 alteration in human esophageal cancer

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12 December 2020

DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1

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12 December 2020

RB and cell cycle progression

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12 December 2020

Multiple mechanisms of p16INK4A inactivation in non-small cell lung cancer cell lines

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12 December 2020

Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor

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12 December 2020

Phosphorylation site mutated RB exerts contrasting effects on apoptotic response to different stimuli

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12 December 2020

Structure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressor

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12 December 2020

A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p

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12 December 2020

Deregulated E2f-2 underlies cell cycle and maturation defects in retinoblastoma null erythroblasts

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12 December 2020

SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family

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12 December 2020

Hypo-phosphorylation of the retinoblastoma protein (pRb) by cyclin D:Cdk4/6 complexes results in active pRb

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12 December 2020

The retinoblastoma protein and cell cycle control

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12 December 2020

PU.1 and pRB Interact and Cooperate To Repress GATA-1 and Block Erythroid Differentiation

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12 December 2020

Histone acetylation in chromatin structure and transcription

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12 December 2020

Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis

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12 December 2020

Coordinated regulation of life and death by RB.

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12 December 2020

Signal-dependent protection from apoptosis in mice expressing caspase-resistant Rb.

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12 December 2020

The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle

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12 December 2020

Acetylation regulates the differentiation-specific functions of the retinoblastoma protein

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12 December 2020

Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages

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12 December 2020

The Molecular Biology Toolkit (MBT): a modular platform for developing molecular visualization applications

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12 December 2020

E2F is required to prevent inappropriate S-phase entry of mammalian cells

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12 December 2020

Cell cycle-dependent phosphorylation of p27 cyclin-dependent kinase (Cdk) inhibitor by cyclin E/Cdk2.

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12 December 2020

Histone deacetylase activity is required for full transcriptional repression by mSin3A

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12 December 2020

The retinoblastoma susceptibility gene product represses transcription when directly bound to the promoter

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12 December 2020

Activity of RNA polymerase I transcription factor UBF blocked by Rb gene product

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12 December 2020

Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases

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12 December 2020

Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes

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12 December 2020

The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase

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12 December 2020

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

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12 December 2020

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F

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12 December 2020

Retinoblastoma family genes

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12 December 2020

Loss of RB compromises specific heterochromatin modifications and modulates HP1alpha dynamics

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12 December 2020

Sequential two-step cleavage of the retinoblastoma protein by caspase-3/-7 during etoposide-induced apoptosis

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12 December 2020

Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression

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12 December 2020

Retinoblastoma family proteins as key targets of the small DNA virus oncoproteins.

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12 December 2020

Amplification and overexpression of the cyclin D1 and epidermal growth factor receptor genes in non-small-cell lung cancer. Lung Cancer Study Group

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12 December 2020

Mechanisms by which DNA tumor virus oncoproteins target the Rb family of pocket proteins

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12 December 2020

What's up and down with histone deacetylation and transcription?

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12 December 2020

Degradation of retinoblastoma protein in tumor necrosis factor- and CD95-induced cell death.

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12 December 2020

Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites

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12 December 2020

Targeting chromatin disruption: Transcription regulators that acetylate histones

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12 December 2020

A retinoblastoma-binding protein related to a negative regulator of Ras in yeast

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12 December 2020

Rb interacts with histone deacetylase to repress transcription

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12 December 2020

Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1

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12 December 2020

Repression of RNA polymerase III transcription by the retinoblastoma protein

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12 December 2020

Chromatin as an essential part of the transcriptional mechanim

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12 December 2020

A role for E2F1 in the induction of ARF, p53, and apoptosis during thymic negative selection

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12 December 2020

Mechanism of active transcriptional repression by the retinoblastoma protein

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12 December 2020

Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation

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12 December 2020

Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition

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12 December 2020

Requirement for a functional Rb-1 gene in murine development

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12 December 2020

Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas

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12 December 2020

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

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12 December 2020

Inactivation of the retinoblastoma tumor suppressor induces apoptosis protease-activating factor-1 dependent and independent apoptotic pathways during embryogenesis.

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12 December 2020

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12 December 2020

Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system

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12 December 2020

The RB and p53 pathways in cancer

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12 December 2020

Cell cycle regulation of retinoblastoma protein phosphorylation

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12 December 2020

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12 December 2020

Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos

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12 December 2020

Histone Deacetylation of RB-Responsive Promoters: Requisite for Specific Gene Repression but Dispensable for Cell Cycle Inhibition

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12 December 2020

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

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12 December 2020

Reduction of apoptosis in Rb-deficient embryos via Abl knockout

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12 December 2020

A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites

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12 December 2020

Retinoblastoma protein recruits histone deacetylase to repress transcription

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12 December 2020

Mitogen-induced rapid phosphorylation of serine 795 of the retinoblastoma gene product in vascular smooth muscle cells involves ERK activation.

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12 December 2020

Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells

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12 December 2020

Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein

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12 December 2020

Retinoblastoma protein switches the E2F site from positive to negative element

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12 December 2020

10.1007/S12038-009-0034-2

Identifiers

DOI

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20 August 2017

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