(Q37548680)

English

Bone marrow-specific knock-in of a non-activatable Ikkα kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice

scientific article published on 03 February 2014

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Bone marrow-specific knock-in of a non-activatable Ikkα kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice (English)

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

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atherosclerosis

1 reference

based on heuristic

inferred from title

object named as

Toby Lawrence

14

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object named as

Rory R Koenen

12

0 references

Christian Weber

object named as

Christian Weber

17

0 references

Pathricia V Tilstam

object named as

Pathricia V Tilstam

1

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16

object named as

Alma Zernecke

1 reference

Europe PubMed Central

21 August 2017

PMC publication ID

Sakine Simsekyilmaz

11

object named as

Sakine Simsekyilmaz

1 reference

Europe PubMed Central

21 August 2017

PMC publication ID

author name string

Marion J Gijbels

2

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Europe PubMed Central

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21 August 2017

Mohamed Habbeddine

3

1 reference

Europe PubMed Central

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21 August 2017

Céline Cudejko

4

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Europe PubMed Central

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21 August 2017

Yaw Asare

5

1 reference

Europe PubMed Central

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21 August 2017

Wendy Theelen

6

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Europe PubMed Central

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21 August 2017

Baixue Zhou

7

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Europe PubMed Central

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21 August 2017

Yvonne Döring

8

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Europe PubMed Central

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21 August 2017

Maik Drechsler

9

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Europe PubMed Central

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21 August 2017

Lukas Pawig

10

1 reference

Europe PubMed Central

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21 August 2017

Menno P J de Winther

13

1 reference

Europe PubMed Central

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21 August 2017

Jürgen Bernhagen

15

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21 August 2017

Heidi Noels

18

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21 August 2017

language of work or name

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publication date

3 February 2014

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Europe PubMed Central

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21 August 2017

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Europe PubMed Central

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21 August 2017

9

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Europe PubMed Central

PMC publication ID

21 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

e87452

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

copyright license

Creative Commons Attribution 4.0 International

3 February 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Cell-intrinsic role for NF-kappa B-inducing kinase in peripheral maintenance but not thymic development of Foxp3+ regulatory T cells in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

B cell subsets in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Effector Memory T cells Are Associated With Atherosclerosis in Humans and Animal Models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

IKKα-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

NIK prevents the development of hypereosinophilic syndrome-like disease in mice independent of IKKα activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Bone marrow p16INK4a-deficiency does not modulate obesity, glucose homeostasis or atherosclerosis development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Depletion of B2 but not B1a B cells in BAFF receptor-deficient ApoE mice attenuates atherosclerosis by potently ameliorating arterial inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Crosstalk in NF-κB signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Apolipoprotein E induces antiinflammatory phenotype in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

The immune system in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

A method for generation of bone marrow-derived macrophages from cryopreserved mouse bone marrow cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

MicroRNAs modulate the noncanonical transcription factor NF-kappaB pathway by regulating expression of the kinase IKKalpha during macrophage differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Tumor necrosis factor receptor associated factor 6 is not required for atherogenesis in mice and does not associate with atherosclerosis in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Macrophage death and defective inflammation resolution in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

The NF-kappaB-independent functions of IKK subunits in immunity and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Dendritic cells in the thymus contribute to T-regulatory cell induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Nuclear factor kappaB signaling in atherogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Canonical pathway of nuclear factor kappa B activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Central memory and effector memory T cell subsets: function, generation, and maintenance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Activators and target genes of Rel/NF-kappaB transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

23 August 2017

Atherosclerosis: current pathogenesis and therapeutic options

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

6 September 2017

An antiinflammatory role for IKKbeta through the inhibition of "classical" macrophage activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

6 September 2017

Proinflammatory stimuli induce IKKalpha-mediated phosphorylation of PIAS1 to restrict inflammation and immunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

14 September 2017

Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

14 September 2017

Isolation and culture of murine macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

25 June 2018

Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

25 June 2018

IkappaB kinase alpha is essential for mature B cell development and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

25 June 2018

Alymphoplasia (aly)-type nuclear factor kappaB-inducing kinase (NIK) causes defects in secondary lymphoid tissue chemokine receptor signaling and homing of peritoneal cells to the gut-associated lymphatic tissue system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

25 June 2018

Limb and skin abnormalities in mice lacking IKKalpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

25 June 2018

BAFF receptor deficiency reduces the development of atherosclerosis in mice--brief report.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

1 September 2018

Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

1 September 2018

Noncanonical NF-kappaB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

1 September 2018

Lipoprotein profiles in plasma and interstitial fluid analyzed with an automated gel-filtration system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

1 September 2018

TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

1 September 2018

NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

1 September 2018

A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

1 September 2018

B-lymphocyte deficiency increases atherosclerosis in LDL receptor-null mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

1 September 2018

Possible new role for NF-kappaB in the resolution of inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911989

1 September 2018

An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent Pathway

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0087452

21 January 2018

Natural regulatory T cells control the development of atherosclerosis in mice

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0087452

21 January 2018

IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0087452

21 January 2018

A selective NFkappaB inhibitor, DHMEQ, reduced atherosclerosis in ApoE-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24498325

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hematopoietic NF- B1 deficiency results in small atherosclerotic lesions with an inflammatory phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/24498325

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukocyte CD40L deficiency affects the CD25(+) CD4 T cell population but does not affect atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24498325

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atherogenesis in mice does not require CD40 ligand from bone marrow-derived cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24498325

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear factor-kappaB immunoreactivity is present in human coronary plaque and enhanced in patients with unstable angina pectoris

1 reference

https://pubmed.ncbi.nlm.nih.gov/24498325

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired function of dendritic cells in alymphoplasia (aly/aly) mice for expansion of CD25+CD4+ regulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24498325

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0087452

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

2014PLoSO...987452T

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

ResearchGate publication ID

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