(Q37552795)

English

Prehospital hypertonic saline resuscitation attenuates the activation and promotes apoptosis of neutrophils in patients with severe traumatic brain injury

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Prehospital hypertonic saline resuscitation attenuates the activation and promotes apoptosis of neutrophils in patients with severe traumatic brain injury (English)

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

traumatic brain injury

0 references

apoptotic process

0 references

1 reference

based on heuristic

inferred from title

7

object named as

David B Hoyt

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Eileen M. Bulger

8

object named as

Eileen M Bulger

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

author name string

Wolfgang G Junger

1

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Shawn G Rhind

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Sandro B Rizoli

3

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Joseph Cuschieri

4

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Andrew J Baker

5

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Pang N Shek

6

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

publication date

1 November 2013

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

40

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

366-374

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Resuscitation of traumatic hemorrhagic shock patients with hypertonic saline-without dextran-inhibits neutrophil and endothelial cell activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Innate immunity in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Increased neutrophil adenosine a3 receptor expression is associated with hemorrhagic shock and injury severity in trauma patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Immune cell regulation by autocrine purinergic signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Out-of-hospital hypertonic resuscitation after traumatic hypovolemic shock: a randomized, placebo controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Out-of-hospital hypertonic resuscitation following severe traumatic brain injury: a randomized controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

A3 adenosine receptor inhibition improves the efficacy of hypertonic saline resuscitation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

150 years of treating severe traumatic brain injury: a systematic review of progress in mortality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Neutrophil spontaneous death is mediated by down-regulation of autocrine signaling through GPCR, PI3Kgamma, ROS, and actin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Hypertonic saline up-regulates A3 adenosine receptor expression of activated neutrophils and increases acute lung injury after sepsis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Moderate and severe traumatic brain injury in adults.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Traumatic brain injury: can the consequences be stopped?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Activation of PI3-kinase/PKB contributes to delay in neutrophil apoptosis after thermal injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Osmotic regulation of cell function and possible clinical applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Neutrophil apoptosis pathways and their modifications in inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Hypertonicity regulates the function of human neutrophils by modulating chemoattractant receptor signaling and activating mitogen-activated protein kinase p38.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

23 August 2017

Hyperosmolar therapy for raised intracranial pressure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

6 September 2017

Hypertonic resuscitation after severe injury: is it of benefit?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

6 September 2017

Neuroinflammation after traumatic brain injury: opportunities for therapeutic intervention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

6 September 2017

Effect of hypertonic saline on apoptosis of polymorphonuclear cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

6 September 2017

Emerging concepts in the pathophysiology of traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

6 September 2017

Neutrophil depletion reduces edema formation and tissue loss following traumatic brain injury in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

25 June 2018

Clinically relevant hypertonicity prevents stored blood- and lipid-mediated delayed neutrophil apoptosis independent of p38 MAPK or caspase-3 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

25 June 2018

Treatment of refractory intracranial hypertension with 23.4% saline in children with severe traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

1 September 2018

Factors predicting functional and cognitive recovery following severe traumatic, anoxic, and cerebrovascular brain damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

1 September 2018

Hypertonic resuscitation improves neuronal and behavioral outcomes after traumatic brain injury plus hemorrhage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

1 September 2018

Inhibition of neutrophil apoptosis by ATP is mediated by the P2Y11 receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

1 September 2018

Hypertonic resuscitation modulates the inflammatory response in patients with traumatic hemorrhagic shock.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

1 September 2018

Hypertonic saline enhances neutrophil elastase release through activation of P2 and A3 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

1 September 2018

A putative osmoreceptor system that controls neutrophil function through the release of ATP, its conversion to adenosine, and activation of A2 adenosine and P2 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

1 September 2018

Suppression of mitochondria-dependent neutrophil apoptosis with thermal injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

1 September 2018

Hypertonicity increases cAMP in PMN and blocks oxidative burst by PKA-dependent and -independent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

1 September 2018

Hypertonic preconditioning inhibits macrophage responsiveness to endotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

1 September 2018

Hypertonic saline resuscitation reduces neutrophil margination by suppressing neutrophil L selectin expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

1 September 2018

A prospective, randomized, and controlled study of fluid management in children with severe head injury: lactated Ringer's solution versus hypertonic saline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

1 September 2018

Intracerebral inflammation after human brain contusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913169

1 September 2018

Effective treatment of refractory intracranial hypertension after traumatic brain injury with repeated boluses of 14.6% hypertonic saline

1 reference

https://pubmed.ncbi.nlm.nih.gov/24088993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prehospital Hypertonic Saline Resuscitation of Patients With Hypotension and Severe Traumatic Brain Injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/24088993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunomodulatory effects of hypertonic resuscitation on the development of lung inflammation following hemorrhagic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/24088993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immunomodulatory effects of hypertonic saline resuscitation in patients sustaining traumatic hemorrhagic shock: a randomized, controlled, double-blinded trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/24088993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small-volume fluid resuscitation with hypertonic saline prevents inflammation but not mortality in a rat model of hemorrhagic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/24088993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiology of traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/24088993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiology of traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/24088993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of neutrophil apoptosis after severe trauma is NFkappabeta dependent

1 reference

https://pubmed.ncbi.nlm.nih.gov/24088993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of hypertonic saline in the treatment of severe refractory posttraumatic intracranial hypertension in pediatric traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/24088993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Severe traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/24088993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1097/SHK.0000000000000038

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

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