(Q37552929)

21 August 2017

1 reference

title

The road to integrative cancer therapies: emergence of a tumor-associated fibroblast protease as a potential therapeutic target in cancer (English)

1 reference

21 August 2017

Ellen Puré

1

1 reference

21 August 2017

language of work or name

English

0 references

publication date

1 August 2009

1 reference

Expert Opinion on Therapeutic Targets

21 August 2017

published in

1 reference

21 August 2017

volume

13

1 reference

21 August 2017

issue

8

1 reference

21 August 2017

page(s)

967-973

1 reference

Modes of resistance to anti-angiogenic therapy

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Cancer immunotherapy by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Significance of tumor-associated stroma in promotion of intratumoral lymphangiogenesis: pivotal role of a hyaluronan-rich tumor microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

The essential role of fibroblasts in esophageal squamous cell carcinoma-induced angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Endothelial-pericyte interactions in angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Tumor stroma and regulation of cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Stromal fibroblasts in cancer initiation and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Friends or foes - bipolar effects of the tumour stroma in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Cysteine cathepsin proteases as pharmacological targets in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Effective immunoconjugate therapy in cancer models targeting a serine protease of tumor fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Peptide substrate profiling defines fibroblast activation protein as an endopeptidase of strict Gly(2)-Pro(1)-cleaving specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Selective inhibition of fibroblast activation protein protease based on dipeptide substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Synthesis and structure-activity relationship of N-alkyl Gly-boro-Pro inhibitors of DPP4, FAP, and DPP7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Ala657 and conserved active site residues promote fibroblast activation protein endopeptidase activity via distinct mechanisms of transition state stabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

FAP-alpha and uPA show different expression patterns in premalignant and malignant esophageal lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

The gene for fibroblast activation protein alpha (FAP), a putative cell surface-bound serine protease expressed in cancer stroma and wound healing, maps to chromosome band 2q23

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Fibroblast activation protein and chronic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Fibroblast activation protein: a serine protease expressed at the remodeling interface in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Cell-surface glycoproteins of human sarcomas: differential expression in normal and malignant tissues and cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Fibroblast activation protein: differential expression and serine protease activity in reactive stromal fibroblasts of melanocytic skin tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Targeted disruption of mouse fibroblast activation protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair-deficient malignant glioma xenograft

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Seprase promotes rapid tumor growth and increased microvessel density in a mouse model of human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Fibroblast activation protein and its relationship to clinical outcome in pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

The role of CD26/dipeptidyl peptidase IV in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Mouse fibroblast activation protein: molecular cloning, alternative splicing and expression in the reactive stroma of epithelial cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Intrahepatic expression of the hepatic stellate cell marker fibroblast activation protein correlates with the degree of fibrosis in hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Antiplasmin-cleaving enzyme is a soluble form of fibroblast activation protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Fibroblast activation protein peptide substrates identified from human collagen I derived gelatin cleavage sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Identification of the 170-kDa melanoma membrane-bound gelatinase (seprase) as a serine integral membrane protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Effect of fibroblast activation protein and alpha2-antiplasmin cleaving enzyme on collagen types I, III, and IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Fibroblast activation protein-alpha and dipeptidyl peptidase IV (CD26): cell-surface proteases that activate cell signaling and are potential targets for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Requirement for Rac1 in a K-ras induced lung cancer in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Use of gene expression profiling to direct in vivo molecular imaging of lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Stromal antigen targeting by a humanised monoclonal antibody: an early phase II trial of sibrotuzumab in patients with metastatic colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Dipeptide proline diphenyl phosphonates are potent, irreversible inhibitors of seprase (FAPalpha).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

PT-100, a small molecule dipeptidyl peptidase inhibitor, has potent antitumor effects and augments antibody-mediated cytotoxicity via a novel immune mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

Emerging roles of proteases in tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903103841

10.1517/14728220903103841

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

1 reference