(Q37570804)

21 August 2017

title

Mammalian target of rapamycin and diabetes: what does the current evidence tell us? (English)

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21 August 2017

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B Vodenik

1

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21 August 2017

J Rovira

series ordinal

2

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21 August 2017

J M Campistol

series ordinal

3

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21 August 2017

language of work or name

English

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publication date

19 July 2009

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Transplantation Proceedings

21 August 2017

published in

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21 August 2017

volume

41

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21 August 2017

issue

6 Suppl

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21 August 2017

page(s)

S31-8

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Diabetes mellitus after renal transplantation: as deleterious as non-transplant-associated diabetes?

21 August 2017

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Glucose intolerance after renal transplantation depends upon prednisolone dose and recipient age.

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Upregulation of the mammalian target of rapamycin complex 1 pathway by Ras homolog enriched in brain in pancreatic beta-cells leads to increased beta-cell mass and prevention of hyperglycemia

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Mammalian Target of Rapamycin Pathway Blockade Slows Progression of Diabetic Kidney Disease in Rats

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7 January 2021

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Rapamycin Has a Deleterious Effect on MIN-6 Cells and Rat and Human Islets

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Decreasing IRS-2 expression in pancreatic β-cells (INS-1) promotes apoptosis, which can be compensated for by introduction of IRS-4 expression

7 January 2021

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7 January 2021

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7 January 2021

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Five-year follow-up after clinical islet transplantation

7 January 2021

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Sirolimus toxicity and vascular endothelial growth factor release from islet and renal cell lines

7 January 2021

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Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation

7 January 2021

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Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes

7 January 2021

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Insulin receptor substrate-2 proteasomal degradation mediated by a mammalian target of rapamycin (mTOR)-induced negative feedback down-regulates protein kinase B-mediated signaling pathway in beta-cells

7 January 2021

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mTORC1 activation regulates beta-cell mass and proliferation by modulation of cyclin D2 synthesis and stability

7 January 2021

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Glucose metabolism in renal transplant recipients: effect of calcineurin inhibitor withdrawal and conversion to sirolimus

7 January 2021

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7 January 2021

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7 January 2021

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Inhibitory effects of immunosuppressive drugs on insulin secretion from HIT-T15 cells and Wistar rat islets

7 January 2021

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Rapamycin impairs beta-cell proliferation in vivo.

7 January 2021

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The role of mTOR in the adaptation and failure of beta-cells in type 2 diabetes

7 January 2021

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MAP kinases and mTOR mediate insulin-induced phosphorylation of insulin receptor substrate-1 on serine residues 307, 612 and 632

7 January 2021

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Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.159

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.159

Amino acid-sensing mTOR signaling is involved in modulation of lipolysis by chronic insulin treatment in adipocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.159

Effect of mTOR inhibitor on body weight: from an experimental rat model to human transplant patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.159

Non-alcoholic steatohepatitis and metabolic syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.159

The mammalian target of rapamycin regulates lipid metabolism in primary cultures of rat hepatocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.159

Sustained activation of the mammalian target of rapamycin nutrient sensing pathway is associated with hepatic insulin resistance, but not with steatosis, in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.159

PTEN down-regulation by unsaturated fatty acids triggers hepatic steatosis via an NF-kappaBp65/mTOR-dependent mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.159

Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.159

Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.159

Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.159

Molecular mechanisms of lipid-induced insulin resistance in muscle, liver and vasculature.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.159

The Mammalian target of rapamycin pathway regulates nutrient-sensitive glucose uptake in man

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.159

Rapamycin does not improve insulin sensitivity despite elevated mammalian target of rapamycin complex 1 activity in muscles of ob/ob mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.159

Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.159

10.1016/J.TRANSPROCEED.2009.06.159

7 January 2021

Identifiers

DOI

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21 August 2017

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