(Q43960077)

28 November 2017

title

IRS-3 inhibits IRS-2-mediated signaling in pancreatic beta-cells (English)

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28 November 2017

Melissa K Lingohr

1

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28 November 2017

Lorna M Dickson

2

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28 November 2017

Christian E Wrede

3

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28 November 2017

Jill F McCuaig

4

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28 November 2017

Martin G Myers

5

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28 November 2017

Christopher J Rhodes

6

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28 November 2017

publication date

1 June 2003

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Molecular and Cellular Endocrinology

28 November 2017

published in

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28 November 2017

volume

204

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28 November 2017

issue

1-2

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28 November 2017

page(s)

85-99

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Different subcellular distribution and regulation of expression of insulin receptor substrate (IRS)-3 from those of IRS-1 and IRS-2

28 November 2017

cites work

1 reference

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7 January 2021

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

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Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

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7 January 2021

Absence of functional insulin receptor substrate-3 (IRS-3) gene in humans.

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7 January 2021

Perspective: Postnatal pancreatic beta cell growth

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7 January 2021

Differential effects of hyperlipidemia on insulin secretion in islets of langerhans from hyperglycemic versus normoglycemic rats

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7 January 2021

IRS proteins and beta-cell function

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7 January 2021

Mammalian TOR: a homeostatic ATP sensor

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7 January 2021

Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1).

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7 January 2021

Mice lacking insulin receptor substrate 4 exhibit mild defects in growth, reproduction, and glucose homeostasis.

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7 January 2021

Glucose, other secretagogues, and nerve growth factor stimulate mitogen-activated protein kinase in the insulin-secreting beta-cell line, INS-1.

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7 January 2021

Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells

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7 January 2021

Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion

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7 January 2021

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

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7 January 2021

Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines

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7 January 2021

A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family

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7 January 2021

Pancreatic beta-cell growth and survival--a role in obesity-linked type 2 diabetes?

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7 January 2021

Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation

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7 January 2021

Insulin receptor substrate 3 is not essential for growth or glucose homeostasis.

1 reference

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7 January 2021

Insulin signal transduction and the IRS proteins

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7 January 2021

Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice

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7 January 2021

Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat

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7 January 2021

Molecular insights into insulin action and secretion

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7 January 2021

IGF-I and GH post-receptor signaling mechanisms for pancreatic beta-cell replication

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7 January 2021

A specific increased expression of insulin receptor substrate 2 in pancreatic beta-cell lines is involved in mediating serum-stimulated beta-cell growth.

1 reference

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7 January 2021

Cloning of the mouse insulin receptor substrate-3 (mIRS-3) promoter, and its regulation by p53.

1 reference

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7 January 2021

Insulin receptor substrate 3 (IRS-3) and IRS-4 impair IRS-1- and IRS-2-mediated signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2803%2900124-2

7 January 2021

Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha

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https://api.crossref.org/works/10.1016%2FS0303-7207%2803%2900124-2

7 January 2021

The IRS-signalling system: a network of docking proteins that mediate insulin action

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7 January 2021

IRS proteins and the common path to diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2803%2900124-2

7 January 2021

Disruption of IRS-2 causes type 2 diabetes in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2803%2900124-2

7 January 2021

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2803%2900124-2

7 January 2021

10.1016/S0303-7207(03)00124-2

Identifiers

DOI

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28 November 2017

1 reference