(Q52174749)

26 April 2018

title

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling. (English)

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26 April 2018

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Withers DJ

1

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26 April 2018

Burks DJ

2

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26 April 2018

Towery HH

3

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26 April 2018

Altamuro SL

4

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26 April 2018

Flint CL

5

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26 April 2018

White MF

6

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26 April 2018

language of work or name

English

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publication date

1 September 1999

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26 April 2018

published in

Nature Genetics

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26 April 2018

volume

23

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26 April 2018

issue

1

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26 April 2018

page(s)

32-40

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26 April 2018

https://scigraph.springernature.com/pub.10.1038/12631

exact match

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cites work

Molecular and cellular aspects of the insulin-like growth factor I receptor

1 reference

7 January 2021

Oncogenes and the strategy of growth factors

1 reference

7 January 2021

IRS-1 is a common element in insulin and insulin-like growth factor-I signaling to the phosphatidylinositol 3'-kinase

1 reference

7 January 2021

Early neonatal death in mice homozygous for a null allele of the insulin receptor gene

1 reference

7 January 2021

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

1 reference

7 January 2021

Role of IRS-2 in insulin and cytokine signalling

1 reference

7 January 2021

Insulin receptor substrate-2 amino acid polymorphisms are not associated with random type 2 diabetes among Caucasians

1 reference

7 January 2021

Disruption of IRS-2 causes type 2 diabetes in mice

1 reference

7 January 2021

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

1 reference

7 January 2021

Insulin signalling and insulin actions in the muscles and livers of insulin-resistant, insulin receptor substrate 1-deficient mice

1 reference

7 January 2021

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

1 reference

7 January 2021

The insulin-like growth factor-I receptor and apoptosis. Implications for the aging progress

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7 January 2021

The pleckstrin homology and phosphotyrosine binding domains of insulin receptor substrate 1 mediate inhibition of apoptosis by insulin

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7 January 2021

Apoptosis contributes to the involution of beta cell mass in the post partum rat pancreas

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7 January 2021

Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat.

1 reference

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

7 January 2021

Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells

1 reference

7 January 2021

Evidence that IRS-2 phosphorylation is required for insulin action in hepatocytes.

1 reference

7 January 2021

A specific increased expression of insulin receptor substrate 2 in pancreatic beta-cell lines is involved in mediating serum-stimulated beta-cell growth.

1 reference

7 January 2021

Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells

1 reference

7 January 2021

Tyr624 and Tyr628 in insulin receptor substrate-2 mediate its association with the insulin receptor

1 reference

7 January 2021

Insulin receptor substrate-2 binds to the insulin receptor through its phosphotyrosine-binding domain and through a newly identified domain comprising amino acids 591-786

1 reference

7 January 2021

Pancreatic islet expression studies and polymorphic DNA markers in the genes encoding hepatocyte nuclear factor-3alpha, -3beta, -3gamma, -4gamma, and -6.

1 reference

7 January 2021

beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

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7 January 2021

Transcribing pancreas.

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7 January 2021

Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1

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7 January 2021

Pancreatic beta-cell growth and diabetes mellitus

1 reference

7 January 2021

Identifiers

DOI

10.1038/12631

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26 April 2018

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26 April 2018