(Q37573820)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19659449%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

review article

1 reference

title

The Hedgehog signalling pathway as a therapeutic target in early breast cancer development (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19659449%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19659449%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

author name string

Sandra A O'Toole

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19659449%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Robert L Sutherland

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19659449%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

language of work or name

English

0 references

publication date

1 September 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19659449%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Targets

4 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19659449%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19659449%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19659449%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

page(s)

1095-1103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19659449%20AND%20SRC:MED&resulttype=core&format=json

Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

4 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Mammary stem cells, self-renewal pathways, and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Hedgehog signaling in mammary gland development and breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Tissue repair and stem cell renewal in carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Hedgehog signalling in prostate regeneration, neoplasia and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Medulloblastoma growth inhibition by hedgehog pathway blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Cancer stem cells: an old idea--a paradigm shift

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Mutations affecting segment number and polarity in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Developmental roles and clinical significance of hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

The hedgehog signaling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Hedgehog: functions and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Short- and long-range effects of Sonic hedgehog in limb development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Sonic Hedgehog as a mediator of long-range signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Cholesterol modification restricts the spread of Shh gradient in the limb bud.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

A freely diffusible form of Sonic hedgehog mediates long-range signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Pathways of signal transduction employed by vertebrate Hedgehogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Hedgehog signalling in the mouse requires intraflagellar transport proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Hedgehog signaling in animal development: paradigms and principles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Novel genes regulated by Sonic Hedgehog in pluripotent mesenchymal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Hedgehog drugs begin to show results

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Teratogen-mediated inhibition of target tissue response to Shh signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Small molecule modulation of Smoothened activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Hedgehog-Gli signaling pathway inhibitors as anticancer agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Activating Smoothened mutations in sporadic basal-cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Hedgehog signaling in the prostate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

A paracrine requirement for hedgehog signalling in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

A primary xenograft model of small-cell lung cancer reveals irreversible changes in gene expression imposed by culture in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Therapeutic inhibition of Hedgehog-GLI signaling in cancer: epithelial, stromal, or stem cell targets?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Hedgehog signalling in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

The Gli2 transcription factor is required for normal mouse mammary gland development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

No evidence for the H133Y mutation in SONIC HEDGEHOG in a collection of common tumour types

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

The patched/hedgehog/smoothened signalling pathway in human breast cancer: no evidence for H133Y SHH, PTCH and SMO mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: pathological significance in early- and late-onset breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Unmasking of epigenetically silenced genes reveals DNA promoter methylation and reduced expression of PTCH in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903130612

10.1517/14728220903130612

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19659449%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference