(Q37579055)

21 August 2017

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title

Mechanistic considerations of halogenating enzymes (English)

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21 August 2017

Alison Butler

1

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author name string

Moriah Sandy

series ordinal

2

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PubMed ID

19675645

21 August 2017

language of work or name

English

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publication date

1 August 2009

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21 August 2017

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21 August 2017

460

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21 August 2017

848-854

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21 August 2017

7257

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https://scigraph.springernature.com/pub.10.1038/nature08303

21 August 2017

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cites work

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Vanadium haloperoxidase-catalyzed bromination and cyclization of terpenes

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Degradation pathway of homoserine lactone bacterial signal molecules by halogen antimicrobials identified by liquid chromatography with photodiode array and mass spectrometric detection

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Nature's inventory of halogenation catalysts: oxidative strategies predominate

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Iodide accumulation provides kelp with an inorganic antioxidant impacting atmospheric chemistry

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Structural perspective on enzymatic halogenation

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The barbamide biosynthetic gene cluster: a novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit

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What's new in enzymatic halogenations

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Quantitating direct chlorine transfer from enzyme to substrate in chloroperoxidase-catalyzed reactions

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Acyl-HSL signal decay: intrinsic to bacterial cell-cell communications

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Identification of intermediates in the catalytic cycle of chloroperoxidase

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12 December 2020

Crystal structure and mechanism of a bacterial fluorinating enzyme

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Vanadium bromoperoxidase-catalyzed biosynthesis of halogenated marine natural products

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The chloroperoxidase from the fungus Curvularia inaequalis; a novel vanadium enzyme

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12 December 2020

Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula

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Enzymatic generation of the antimetabolite gamma,gamma-dichloroaminobutyrate by NRPS and mononuclear iron halogenase action in a streptomycete.

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Enzymatic fluorination in Streptomyces cattleya takes place with an inversion of configuration consistent with an SN2 reaction mechanism

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12 December 2020

The crystal structure of chloroperoxidase: a heme peroxidase--cytochrome P450 functional hybrid

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Marine natural products

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cDNA cloning of Batis maritima methyl chloride transferase and purification of the enzyme

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Discovery and characterization of a marine bacterial SAM-dependent chlorinase

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Chloroperoxidase. II. Utilization of halogen anions

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SyrB2 in syringomycin E biosynthesis is a nonheme FeII alpha-ketoglutarate- and O2-dependent halogenase

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X-ray structure determination of a vanadium-dependent haloperoxidase from Ascophyllum nodosum at 2.0 A resolution

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Crystal structure of dodecameric vanadium-dependent bromoperoxidase from the red algae Corallina officinalis

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The role of vanadium bromoperoxidase in the biosynthesis of halogenated marine natural products

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Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis

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Reaction of acylated homoserine lactone bacterial signaling molecules with oxidized halogen antimicrobials

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Notomastus lobatus chloroperoxidase and Amphitrite ornata dehaloperoxidase both contain histidine as their proximal heme iron ligand

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Halogenation strategies in natural product biosynthesis

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Heterologous Expression of the Vanadium-containing Chloroperoxidase fromCurvularia inaequalisinSaccharomyces cerevisiaeand Site-directed Mutagenesis of the Active Site Residues His496, Lys353, Arg360, and Arg490

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Chlorination of lignin by ubiquitous fungi has a likely role in global organochlorine production

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The fluorinase from Streptomyces cattleya is also a chlorinase

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Biohalogenation: nature's way to synthesize halogenated metabolites

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Metamorphic enzyme assembly in polyketide diversification

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Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis

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The HAG mechanism: a molecular rationale for the therapeutic application of iron chelators in human diseases involving the 2-oxoacid utilizing dioxygenases

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X-ray structure of a vanadium-containing enzyme: chloroperoxidase from the fungus Curvularia inaequalis

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Molecular basis for chloronium-mediated meroterpene cyclization: cloning, sequencing, and heterologous expression of the napyradiomycin biosynthetic gene cluster

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Structure and biosynthesis of the jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium Lyngbya majuscula

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Catalytic mechanisms, basic roles, and biotechnological and environmental significance of halogenating enzymes

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Naturally Occurring Organohalogen Compounds†

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Crossref

https://api.crossref.org/works/10.1038%2FNATURE08303

7 January 2021

inferred from DOI database lookup

Functional Models for Vanadium Haloperoxidase: Reactivity and Mechanism of Halide Oxidation

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE08303

7 January 2021

inferred from DOI database lookup

Evidence for organic substrate binding to vanadium bromoperoxidase

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE08303

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE08303

1 reference

PubMed ID

19675645

Dimensions Publication ID

21 August 2017

0 references

1 reference

PubMed ID

19675645