(Q37579376)

21 August 2017

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title

Emerging concepts in neural stem cell research: autologous repair and cell-based disease modelling (English)

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21 August 2017

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4

Oliver Brüstle

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21 August 2017

Philipp Koch

1

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21 August 2017

Zaal Kokaia

series ordinal

2

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21 August 2017

Olle Lindvall

series ordinal

3

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21 August 2017

publication date

1 September 2009

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21 August 2017

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21 August 2017

volume

8

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21 August 2017

issue

9

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21 August 2017

page(s)

819-829

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Isolation and production of cells suitable for human therapy: challenges ahead.

21 August 2017

cites work

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7 January 2021

Stem cell therapy for human neurodegenerative disorders-how to make it work

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7 January 2021

Prospects of stem cell therapy for replacing dopamine neurons in Parkinson's disease

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7 January 2021

Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system

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7 January 2021

Mammalian neural stem cells

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7 January 2021

Growth factors regulate the survival and fate of cells derived from human neurospheres.

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7 January 2021

Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture

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7 January 2021

Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes.

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7 January 2021

Human progenitor cells isolated from the developing cortex undergo decreased neurogenesis and eventual senescence following expansion in vitro

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7 January 2021

GABAergic immunoreactivity is predominant in neurons derived from expanded human neural precursor cells in vitro.

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7 January 2021

Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro

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7 January 2021

Cell types to order: temporal specification of CNS stem cells

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7 January 2021

Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development

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7 January 2021

Embryonic stem cell lines derived from human blastocysts

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7 January 2021

Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture

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7 January 2021

Pluripotency of spermatogonial stem cells from adult mouse testis

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https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Generation of functional multipotent adult stem cells from GPR125+ germline progenitors

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https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Generation of pluripotent stem cells from adult human testis.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Generation of germline-competent induced pluripotent stem cells

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https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

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7 January 2021

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

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https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Induced pluripotent stem cell lines derived from human somatic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Reprogramming of human somatic cells to pluripotency with defined factors

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Neural progenitors from human embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

In vitro differentiation of transplantable neural precursors from human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Derivation of midbrain dopamine neurons from human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Specification of motoneurons from human embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Human embryonic stem cell-derived oligodendrocyte progenitor cell transplants remyelinate and restore locomotion after spinal cord injury

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Human oligodendrocytes from embryonic stem cells: conserved SHH signaling networks and divergent FGF effects

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Human embryonic stem cell-derived dopaminergic neurons reverse functional deficit in parkinsonian rats

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Embryonic stem cell-based reduction of central nervous system sulfatide storage in an animal model of metachromatic leukodystrophy.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Suppression of kindling epileptogenesis by adenosine releasing stem cell-derived brain implants.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Human embryonic stem cells reveal recurrent genomic instability at 20q11.21.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Epigenetic instability in ES cells and cloned mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Marked differences in differentiation propensity among human embryonic stem cell lines

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https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Banking on human embryonic stem cells: estimating the number of donor cell lines needed for HLA matching

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Induced pluripotent stem cells generated without viral integration

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Human induced pluripotent stem cells free of vector and transgene sequences

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Generation of induced pluripotent stem cells using recombinant proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Breakthrough of the year. Reprogramming Cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

HLA-haplotype banking and iPS cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Variation in the safety of induced pluripotent stem cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Generation of pluripotent stem cells from neonatal mouse testis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Induction of pluripotency in adult unipotent germline stem cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Adult germ line stem cells as a source of functional neurons and glia.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Cell therapy in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Therapeutic cloning in individual parkinsonian mice

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Persistent dopamine functions of neurons derived from embryonic stem cells in a rodent model of Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Induction of A9 dopaminergic neurons from neural stem cells improves motor function in an animal model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

In vitro generation and transplantation of precursor-derived human dopamine neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Generation of functional dopamine neurons from neural precursor cells isolated from the subventricular zone and white matter of the adult rat brain using Nurr1 overexpression.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Identification of intrinsic determinants of midbrain dopamine neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

The homeodomain transcription factor Pitx3 facilitates differentiation of mouse embryonic stem cells into AHD2-expressing dopaminergic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Isolation and transplantation of dopaminergic neurons generated from mouse embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Factors affecting the clinical outcome after neural transplantation in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Dyskinesias following neural transplantation in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Transplantation of embryonic dopamine neurons for severe Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Impact of grafted serotonin and dopamine neurons on development of L-DOPA-induced dyskinesias in parkinsonian rats is determined by the extent of dopamine neuron degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Stages in the development of Parkinson's disease-related pathology

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Challenges in Parkinson's disease: restoration of the nigrostriatal dopamine system is not enough

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Neural stem/precursor cells for the treatment of ischemic stroke.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Adherent self-renewable human embryonic stem cell-derived neural stem cell line: functional engraftment in experimental stroke model

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Molecular and magnetic resonance imaging of human embryonic stem cell-derived neural stem cell grafts in ischemic rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Neuronal differentiation of transplanted embryonic stem cell-derived precursors in stroke lesions of adult rats

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Human fetal cortical and striatal neural stem cells generate region-specific neurons in vitro and differentiate extensively to neurons after intrastriatal transplantation in neonatal rats.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Survival, migration and neuronal differentiation of human fetal striatal and cortical neural stem cells grafted in stroke-damaged rat striatum

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Pax6 promotes neurogenesis in human neural stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Anti-inflammatory mechanism of intravascular neural stem cell transplantation in haemorrhagic stroke

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Human neural stem cells over-expressing VEGF provide neuroprotection, angiogenesis and functional recovery in mouse stroke model

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Human neural stem cells genetically modified to overexpress Akt1 provide neuroprotection and functional improvement in mouse stroke model

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Therapeutic benefits by human mesenchymal stem cells (hMSCs) and Ang-1 gene-modified hMSCs after cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Neuroprotective effects of mesenchymal stem cells derived from human embryonic stem cells in transient focal cerebral ischemia in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Stem cell therapy in stroke.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Clonal human (hNT) neuron grafts for stroke therapy: neuropathology in a patient 27 months after implantation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Transplantation of cultured human neuronal cells for patients with stroke

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Neurotransplantation for patients with subcortical motor stroke: a phase 2 randomized trial

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Autologous mesenchymal stem cell transplantation in stroke patients

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

A conditionally immortal clonal stem cell line from human cortical neuroepithelium for the treatment of ischemic stroke

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Using human neural stem cells to model neurological disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

The mousetrap: what we can learn when the mouse model does not mimic the human disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

A randomized sequential trial of creatine in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Transduction of human neural progenitor cells using recombinant adeno-associated viral vectors

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Human embryonic stem cell lines with genetic disorders

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Molecular biology of amyotrophic lateral sclerosis: insights from genetics

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Alzheimer's disease and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Disease-specific induced pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

Induced pluripotent stem cells from a spinal muscular atrophy patient

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970202-9

7 January 2021

10.1016/S1474-4422(09)70202-9

Identifiers

DOI

1 reference

21 August 2017

1 reference