(Q37582391)

21 August 2017

1 reference

title

Stearoyl-CoA desaturase inhibitors: update on patented compounds (English)

1 reference

21 August 2017

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Gang Liu

1

1 reference

PubMed ID

19691439

21 August 2017

language of work or name

English

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publication date

1 September 2009

1 reference

Expert Opinion on Therapeutic Patents

21 August 2017

1 reference

21 August 2017

19

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21 August 2017

1169-1191

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21 August 2017

9

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Role of stearoyl-coenzyme A desaturase in lipid metabolism

21 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Stearoyl-CoA desaturase as a new drug target for obesity treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Scd3--a novel gene of the stearoyl-CoA desaturase family with restricted expression in skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Identification and characterization of a novel gene disrupted by a pericentric inversion inv(4)(p13.1q21.1) in a family with cleft lip.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Oleoyl-CoA is the major de novo product of stearoyl-CoA desaturase 1 gene isoform and substrate for the biosynthesis of the Harderian gland 1-alkyl-2,3-diacylglycerol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Loss of stearoyl-CoA desaturase-1 improves insulin sensitivity in lean mice but worsens diabetes in leptin-deficient obese mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Critical role of stearoyl-CoA desaturase-1 (SCD1) in the onset of diet-induced hepatic insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Obesity resistance of the stearoyl-CoA desaturase-deficient (scd1-/-) mouse results from disruption of the epidermal lipid barrier and adaptive thermoregulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Effects of sterculic acid on stearoyl-CoA desaturase in differentiating 3T3-L1 adipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Discovery of potent, selective, orally bioavailable stearoyl-CoA desaturase 1 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Discovery of 1-(4-phenoxypiperidin-1-yl)-2-arylaminoethanone stearoyl-CoA desaturase 1 inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Association of stearoyl-CoA desaturase 1 activity with familial combined hyperlipidemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Low hepatic stearoyl-CoA desaturase 1 activity is associated with fatty liver and insulin resistance in obese humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Inhibition of stearoyl-coenzyme A desaturase 1 dissociates insulin resistance and obesity from atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

Induction of stearoyl-CoA desaturase protects human arterial endothelial cells against lipotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903061311

10.1517/13543770903061311

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

1 reference

PubMed ID

19691439