(Q37591216)

21 August 2017

2 references

21 March 2019

17 December 2019

Evidence for a potential role of metallothioneins in inflammatory bowel diseases (English)

1 reference

inflammatory bowel diseases

21 August 2017

2 references

21 March 2019

17 December 2019

0 references

1 reference

17 December 2019

Debby Laukens

3

0 references

author name string

Anouk Waeytens

series ordinal

1

1 reference

PMC publication ID

2734936

21 August 2017

Martine De Vos

series ordinal

2

1 reference

21 August 2017

26 August 2009

3 references

Mediators of Inflammation

21 August 2017

21 March 2019

17 December 2019

3 references

21 August 2017

21 March 2019

17 December 2019

2009

1 reference

21 August 2017

729172

1 reference

Creative Commons Attribution 3.0 Unported

21 August 2017

2 references

21 March 2019

on focus list of Wikimedia project

17 December 2019

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

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23 August 2017

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23 August 2017

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23 August 2017

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Metallothionein and liver cell regeneration

23 August 2017

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Metallothionein mediates leukocyte chemotaxis

23 August 2017

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Redox regulation of NF-kappaB activation: distinct redox regulation between the cytoplasm and the nucleus

23 August 2017

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Protective role of metallothionein in acute lung injury induced by bacterial endotoxin

23 August 2017

1 reference

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Superoxide dismutase ameliorates TNBS-induced colitis by reducing oxidative stress, adhesion molecule expression, and leukocyte recruitment into the inflamed intestine.

23 August 2017

1 reference

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Functional differentiation in the mammalian metallothionein gene family: metal binding features of mouse MT4 and comparison with its paralog MT1

23 August 2017

1 reference

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Zinc-induced NF-kappaB inhibition can be modulated by changes in the intracellular metallothionein level

23 August 2017

1 reference

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Review article: nutrition and adult inflammatory bowel disease

23 August 2017

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Metallothionein: the multipurpose protein

23 August 2017

1 reference

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Brain-specific metallothionein-3 has higher metal-binding capacity than ubiquitous metallothioneins and binds metals noncooperatively

23 August 2017

1 reference

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A mediator role for metallothionein in tumor necrosis factor-induced lethal shock.

23 August 2017

1 reference

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Zinc supplementation tightens "leaky gut" in Crohn's disease

23 August 2017

1 reference

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Influence of metallothionein-1 localization on its function

23 August 2017

2 references

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23 August 2017

https://api.crossref.org/works/10.1155%2F2009%2F729172

Sensitivity of metallothionein-null mice to LPS/D-galactosamine-induced lethality

21 January 2018

1 reference

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Induction, regulation, degradation, and biological significance of mammalian metallothioneins.

23 August 2017

1 reference

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Regulation of metallothionein gene expression by oxidative stress and metal ions

23 August 2017

1 reference

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The ATP-metallothionein complex

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Expression of the gene encoding metallothionein-3 in organs of the reproductive system

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Cell cycle regulation of metallothionein in human colonic cancer cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Human metallothionein genes are clustered on chromosome 16

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Cell specificity and an effect of ras on human metallothionein gene expression

23 August 2017

1 reference

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Tissue-specific regulation of zinc metabolism and metallothionein genes by interleukin 1

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Interleukin 6 regulates metallothionein gene expression and zinc metabolism in hepatocyte monolayer cultures

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Role of reactive oxygen metabolites in experimental colitis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Decrease in two intestinal copper/zinc containing proteins with antioxidant function in inflammatory bowel disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

1 Introduction to metallothionein

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Role of neutrophil-derived oxidants in the pathogenesis of intestinal inflammation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer's disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Amino-acid sequence of equine renal metallothionein-1B

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Preservation of intestinal structural integrity by zinc is independent of metallothionein in alcohol-intoxicated mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Ulcerative colitis and Crohn's disease: distinctive gene expression profiles and novel susceptibility candidate genes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Regulatory role of metallothionein in NF-kappaB activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Activation of nuclear factor kappaB: potential role in metallothionein-mediated mitogenic response.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Quantitative measurement of cytokine mRNA in inflammatory bowel disease: relation to clinical and endoscopic activity and outcome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Antioxidant effect of zinc in humans

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Effects of zinc deficiency on Th1 and Th2 cytokine shifts

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Effects of exogenous zinc supplementation on intestinal epithelial repair in vitro

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Metallothionein-induced suppression of cytotoxic T lymphocyte function: an important immunoregulatory control

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Blocking effect of anti-mouse interleukin-6 monoclonal antibody and glucocorticoid receptor antagonist, RU38486, on metallothionein-inducing activity of serum from lipopolysaccharide-treated mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Mechanism of metallothionein gene regulation by heme-hemopexin. Roles of protein kinase C, reactive oxygen species, and cis-acting elements

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Effects of the non-peptidyl low molecular weight radical scavenger IAC in DNBS-induced colitis in rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Metallothionein modulates lipopolysaccharide-stimulated tumour necrosis factor expression in mouse peritoneal macrophages

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Transient peaks in zinc and metallothionein levels during differentiation of 3T3L1 cells

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Zinc and immune function: the biological basis of altered resistance to infection

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Altered plasma and mucosal concentrations of trace elements and antioxidants in active ulcerative colitis.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Metallothionein: a protein conferring resistance in vitro to tumor necrosis factor.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Histological demonstration of immunoreactive zinc metallothionein in liver and ileum of rat and man.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Histological demonstration of immunoreactive metallothionein in rat and human tissues.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Extracellular metallothionein effects on lymphocyte activities

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Endotoxin induction of murine metallothionein gene expression

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

The influence of zinc status and malnutrition on immunological function in Crohn's disease

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Cell-type specific and differential regulation of the human metallothionein genes. Correlation with DNA methylation and chromatin structure

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Oxidative stress-induced disruption of epithelial and endothelial tight junctions.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Role of metallothionein in coagulatory disturbance and systemic inflammation induced by lipopolysaccharide in mice.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Polaprezinc (N-(3-aminopropionyl)-L-histidinato zinc) ameliorates dextran sulfate sodium-induced colitis in mice

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Preliminary studies on the zinc-induced metallothionein protein with antibacterial activity in housefly larvae, Musca domestica

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Reduced bactericidal activity and nitric oxide production in metallothionein-deficient macrophages in response to lipopolysaccharide stimulation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Metallothionein overexpression does not protect against inflammatory bowel disease in a murine colitis model

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Regulation of gene expression in inflammatory bowel disease and correlation with IBD drugs: screening by DNA microarrays

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Intestinal oxidative damage in inflammatory bowel disease: semi-quantification, localization, and association with mucosal antioxidants

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Imbalanced secondary mucosal antioxidant response in inflammatory bowel disease

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Property of metallothionein as a Zn pool differs depending on the induced condition of metallothionein

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Attenuated mild colonic inflammation and improved survival from severe DSS-colitis of transgenic Cu/Zn-SOD mice

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Metallothionein is required for zinc-induced expression of the macrophage colony stimulating factor gene

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Delineation of the protective action of zinc sulfate on ulcerative colitis in rats.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Effect of zinc supplementation on intestinal permeability in experimental colitis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Altered inflammatory response and increased neurodegeneration in metallothionein I+II deficient mice during experimental autoimmune encephalomyelitis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Increased expression of metallothionein in inflammatory bowel disease

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Oxidative burst and metallothionein as a scavenger in macrophages

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Effect of zinc supplementation on trace elements and intestinal metallothionein concentrations in experimental colitis in the rat.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Augmented humoral immune function in metallothionein-null mice.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Expression of MT-3 mRNA in human kidney, proximal tubule cell cultures, and renal cell carcinoma

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2734936

Nutrition and adult inflammatory bowel disease

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2009%2F729172

The Physiological Roles of Extracellular Metallothionein

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2009%2F729172

Metallothionein Treatment Reduces Proinflammatory Cytokines IL-6 and TNF-α and Apoptotic Cell Death during Experimental Autoimmune Encephalomyelitis (EAE)

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2009%2F729172

A20 zinc finger protein inhibits TNF and IL-1 signaling

21 January 2018

1 reference

12 December 2020

Nitric oxide mediated metallothionein induction by lipopolysaccharide

1 reference

12 December 2020

Interactions of metallothionein with murine lymphocytes: plasma membrane binding and proliferation

1 reference

12 December 2020

Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease

1 reference

12 December 2020

Zinc deficiency in Crohn's disease

1 reference

12 December 2020

Down-regulation of endothelial adhesion molecules and leukocyte adhesion by treatment with superoxide dismutase is beneficial in chronic immune experimental colitis

1 reference

12 December 2020

Alterations in Salivary Antioxidants, Nitric Oxide, and Transforming Growth Factor-β1in Relation to Disease Activity in Crohn's Disease Patients

1 reference

12 December 2020

Imbalance of the antioxidant network of mouse small intestinal mucosa after radiation exposure

1 reference

12 December 2020

The role of zinc and metallothionein in the dextran sulfate sodium-induced colitis mouse model

1 reference

12 December 2020

Anti-inflammatory properties of Lactobacillus gasseri expressing manganese superoxide dismutase using the interleukin 10-deficient mouse model of colitis

1 reference

12 December 2020

Functions of metallothionein generating interleukin-10-producing regulatory CD4+ T cells potentiate suppression of collagen-induced arthritis

1 reference

12 December 2020

Immune system alterations in patients with inflammatory bowel disease during remission

1 reference

12 December 2020

Increased intestinal permeability in patients with Crohn's disease and their relatives. A possible etiologic factor

1 reference

12 December 2020

Localization of metallothionein in nuclei of growing primary cultured adult rat hepatocytes

1 reference

12 December 2020

Immunomodulatory activities of extracellular metallothionein. I. Metallothionein effects on antibody production

1 reference

12 December 2020

Differential induction of metallothionein synthesis by interleukin-6 and tumor necrosis factor-alpha in rat tissues

1 reference

12 December 2020

Effect of oral zinc supplementation on metallothionein and superoxide dismutase concentrations in patients with inflammatory bowel disease

1 reference

12 December 2020

Zinc sulphate solution enema decreases inflammation in experimental colitis in rats

1 reference

12 December 2020

In vivo manipulation of endogenous metallothionein with a monoclonal antibody enhances a T-dependent humoral immune response

1 reference

12 December 2020

Metallothionein suppresses collagen-induced arthritis via induction of TGF-beta and down-regulation of proinflammatory mediators

1 reference

12 December 2020

The immunohistochemical expression of metallothionein in inflammatory bowel disease. Correlation with HLA-DR antigen expression, lymphocyte subpopulations and proliferation-associated indices

1 reference

12 December 2020

Helicobacter‐induced Gastritis in Mice Not Expressing Metallothionein‐I and II*

1 reference

12 December 2020

Identifiers

DOI

10.1155/2009/729172

1 reference

21 August 2017

1 reference

PMC publication ID

2734936

21 August 2017

PubMed publication ID

19727408

1 reference

PMC publication ID

2734936