(Q37592077)

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Reexpression of tumor suppressor, sFRP1, leads to antitumor synergy of combined HDAC and methyltransferase inhibitors in chemoresistant cancers.

scientific article published on 23 July 2012

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8 February 2020

Reexpression of tumor suppressor, sFRP1, leads to antitumor synergy of combined HDAC and methyltransferase inhibitors in chemoresistant cancers (English)

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8 February 2020

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8 February 2020

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Simon J Cooper

1

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8 February 2020

Christina A von Roemeling

2

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8 February 2020

Kylie H Kang

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8 February 2020

Stefan K Grebe

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8 February 2020

Michael E Menefee

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8 February 2020

Han W Tun

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8 February 2020

Gerardo Colon-Otero

8

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8 February 2020

Edith A Perez

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8 February 2020

John A Copland

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8 February 2020

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23 July 2012

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8 February 2020

Molecular Cancer Therapeutics

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8 February 2020

11

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8 February 2020

10

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8 February 2020

2105-2115

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8 February 2020

describes a project that uses

0 references

Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928542

23 August 2017

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1 reference

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23 August 2017

Signaling pathways in renal cell carcinoma

1 reference

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23 August 2017

Detailed molecular fingerprinting of four new anaplastic thyroid carcinoma cell lines and their use for verification of RhoB as a molecular therapeutic target

1 reference

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23 August 2017

WNT signaling enhances breast cancer cell motility and blockade of the WNT pathway by sFRP1 suppresses MDA-MB-231 xenograft growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928542

23 August 2017

Wnt signal transduction pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928542

23 August 2017

Reactivation of suppressed RhoB is a critical step for the inhibition of anaplastic thyroid cancer growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928542

23 August 2017

Promoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancer

1 reference

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1 reference

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23 August 2017

Epigenetic inactivation of the secreted frizzled-related protein-5 (SFRP5) gene in human breast cancer is associated with unfavorable prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928542

23 August 2017

Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease

1 reference

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23 August 2017

Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer

1 reference

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23 August 2017

Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928542

23 August 2017

Secreted frizzled-related protein 1 loss contributes to tumor phenotype of clear cell renal cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928542

23 August 2017

SFRP1 suppressed hepatoma cells growth through Wnt canonical signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928542

23 August 2017

Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation

1 reference

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23 August 2017

Aberrant methylation of the Wnt antagonist SFRP1 in breast cancer is associated with unfavourable prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928542

23 August 2017

FK228 (depsipeptide): a HDAC inhibitor with pleiotropic antitumor activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928542

23 August 2017

Epigenetic suppression of secreted frizzled related protein 1 (SFRP1) expression in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928542

23 August 2017

Wnt signaling through canonical and non-canonical pathways: recent progress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928542

23 August 2017

Transcriptional silencing of secreted frizzled related protein 1 (SFRP 1) by promoter hypermethylation in non-small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928542

23 August 2017

Novel treatments for metastatic renal cell carcinoma

1 reference

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23 August 2017

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928542

23 August 2017

Gene silencing in cancer in association with promoter hypermethylation

1 reference

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23 August 2017

5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy

1 reference

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Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms

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The changing natural history of renal cell carcinoma

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

1 reference

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Loss of type III transforming growth factor-beta receptor expression is due to methylation silencing of the transcription factor GATA3 in renal cell carcinoma

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1 reference

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Secreted frizzled-related protein-5 is epigenetically downregulated and functions as a tumor suppressor in kidney cancer

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Identification of candidate tumour suppressor genes frequently methylated in renal cell carcinoma

1 reference

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Methylation-associated silencing of SFRP1 in renal cell carcinoma.

1 reference

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DNA methylation and histone modifications cause silencing of Wnt antagonist gene in human renal cell carcinoma cell lines

1 reference

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DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.

1 reference

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Methylation-associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers.

1 reference

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14 September 2017

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22826467

12 December 2020

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10.1158/1535-7163.MCT-11-0873

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Europe PubMed Central

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8 February 2020

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8 February 2020

PubMed publication ID

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22826467%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

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