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English
Two mutant prion proteins expressed in cultured cells acquire biochemical properties reminiscent of the scrapie isoform.
scientific article published on May 1996
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
39295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643624%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
title
Two mutant prion proteins expressed in cultured cells acquire biochemical properties reminiscent of the scrapie isoform
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
39295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643624%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
main subject
prion protein family
0 references
author
David A Harris
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
39295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643624%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
author name string
S Lehmann
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
39295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643624%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
language of work or name
English
0 references
publication date
1 May 1996
1 reference
stated in
Europe PubMed Central
PMC publication ID
39295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643624%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
Europe PubMed Central
PMC publication ID
39295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643624%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
volume
93
1 reference
stated in
Europe PubMed Central
PMC publication ID
39295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643624%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
issue
11
1 reference
stated in
Europe PubMed Central
PMC publication ID
39295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643624%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
page(s)
5610-5614
1 reference
stated in
Europe PubMed Central
PMC publication ID
39295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643624%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
cites work
Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
23 August 2017
Mice devoid of PrP are resistant to scrapie
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
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23 August 2017
Structural clues to prion replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
23 August 2017
Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
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23 August 2017
Inherited Creutzfeldt-Jakob disease in a British family associated with a novel 144 base pair insertion of the prion protein gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
23 August 2017
Species specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrier
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
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23 August 2017
Novel proteinaceous infectious particles cause scrapie
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
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23 August 2017
Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
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23 August 2017
Analyses of frequency of infection, specific infectivity, and prion protein biosynthesis in scrapie-infected neuroblastoma cell clones
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
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23 August 2017
A cellular gene encodes scrapie PrP 27-30 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
23 August 2017
Molecular location of a species-specific epitope on the hamster scrapie agent protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
23 August 2017
Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
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23 August 2017
N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): implications regarding the site of conversion of PrP to the protease-resistant state
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
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23 August 2017
Synthesis and trafficking of prion proteins in cultured cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
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23 August 2017
Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
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23 August 2017
Inherited prion disease (PrP lysine 200) in Britain: two case reports
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
6 September 2017
A Mutant Prion Protein Displays an Aberrant Membrane Association When Expressed in Cultured Cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
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6 September 2017
Mutation of the prion protein in Libyan Jews with Creutzfeldt-Jakob disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
6 September 2017
Presence of prion protein in peripheral tissues of Libyan Jews with Creutzfeldt-Jakob disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
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6 September 2017
Prion diseases and neurodegeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
28 September 2017
Mutant and infectious prion proteins display common biochemical properties in cultured cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
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28 September 2017
Human spongiform encephalopathy: the National Institutes of Health series of 300 cases of experimentally transmitted disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
25 June 2018
Japanese family with Creutzfeldt-Jakob disease with codon 200 point mutation of the prion protein gene.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
25 June 2018
Isolation and structural studies of the intact scrapie agent protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
25 June 2018
An in-frame insertion in the prion protein gene in familial Creutzfeldt-Jakob disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
25 June 2018
Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
25 June 2018
Creutzfeldt-Jacob disease associated with the PRNP codon 200Lys mutation: an analysis of 45 families
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
25 June 2018
Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
25 June 2018
Evidence for synthesis of scrapie prion proteins in the endocytic pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
25 June 2018
Inherited prion disease with 144 base pair gene insertion. 2. Clinical and pathological features.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
25 June 2018
Inherited prion disease with 144 base pair gene insertion. 1. Genealogical and molecular studies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
25 June 2018
Processing of a cellular prion protein: identification of N- and C-terminal cleavage sites.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
1 September 2018
Prion disease with 144 base pair insertion in a Japanese family line
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39295
retrieved
1 September 2018
The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8643624
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Conformational transitions, dissociation, and unfolding of scrapie amyloid (prion) protein
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8643624
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Human prion diseases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8643624
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.93.11.5610
1 reference
stated in
Europe PubMed Central
PMC publication ID
39295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643624%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
ADS bibcode
1996PNAS...93.5610L
0 references
PMC publication ID
39295
1 reference
stated in
Europe PubMed Central
PMC publication ID
39295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643624%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
PubMed publication ID
8643624
1 reference
stated in
Europe PubMed Central
PMC publication ID
39295
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643624%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
ResearchGate publication ID
14556188
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