(Q37594369)

21 August 2017

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title

Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation (English)

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21 August 2017

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3

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21 August 2017

G Solinas

1

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21 August 2017

G Germano

series ordinal

2

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21 August 2017

P Allavena

series ordinal

4

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21 August 2017

publication date

9 September 2009

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Journal of Leukocyte Biology

21 August 2017

published in

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21 August 2017

volume

86

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21 August 2017

issue

5

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21 August 2017

page(s)

1065-1073

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Other functions, other genes: alternative activation of antigen-presenting cells

21 August 2017

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Macrophage polarization comes of age.

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Alternative activation of macrophages: an immunologic functional perspective

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Tumour-educated macrophages promote tumour progression and metastasis

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Inflammatory cell infiltration of tumors: Jekyll or Hyde

21 January 2018

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The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies

21 January 2018

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Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression

21 January 2018

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Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

21 January 2018

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Macrophages define the invasive microenvironment in breast cancer

21 January 2018

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A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer

21 January 2018

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Prediction of Survival in Follicular Lymphoma Based on Molecular Features of Tumor-Infiltrating Immune Cells

21 January 2018

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Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0609385

Macrophages regulate the angiogenic switch in a mouse model of breast cancer

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0609385

Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0609385

Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0609385

Cancer and the chemokine network

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0609385

The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Effector memory T cells, early metastasis, and survival in colorectal cancer

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0609385

Heparanase expression, degradation of basement membrane and low degree of infiltration by immunocytes correlate with invasion and progression of human gastric cancer

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0609385

Inhibition of tumor growth by elimination of granulocytes

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0609385

Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0609385

Tumor-induced immune dysfunctions caused by myeloid suppressor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Altered macrophage differentiation and immune dysfunction in tumor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

The terminology issue for myeloid-derived suppressor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Inflammation and cancer: back to Virchow?

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

21 January 2018

Inflammation and cancer

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Smoldering and polarized inflammation in the initiation and promotion of malignant disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Nuclear factor-kappaB in cancer development and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Inflammation and cancer: how hot is the link?

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Immune cells as mediators of solid tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Cancer-related inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Pathways connecting inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

CSF-1 regulation of the wandering macrophage: complexity in action

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

New vistas on macrophage differentiation and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

The chemokine system in diverse forms of macrophage activation and polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Alternatively activated macrophages in protozoan infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

The origin and function of tumor-associated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

The detection and localization of monocyte chemoattractant protein-1 (MCP-1) in human ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Targeting myelomonocytic cells to revert inflammation-dependent cancer promotion

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Evidence of systemic Th2-driven chronic inflammation in patients with metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Interleukin-13-induced type II polarization of inflammatory macrophages is mediated through suppression of nuclear factor-kappaB and preservation of IkappaBalpha in a T cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Eotaxin-2 and colorectal cancer: a potential target for immune therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Contextual regulation of inflammation: a duet by transforming growth factor-beta and interleukin-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Papillary carcinoma of the thyroid: hepatocyte growth factor (HGF) stimulates tumor cells to release chemokines active in recruiting dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation).

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Common transcriptional signature of tumor-infiltrating mononuclear inflammatory cells and peripheral blood mononuclear cells in hepatocellular carcinoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

The macrophage colony-stimulating factor 1 response signature in breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Macrophage responses to hypoxia: implications for tumor progression and anti-cancer therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Regulation of the chemokine receptor CXCR4 by hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Macrophages and the hypoxic tumour microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

HIF-1alpha is essential for myeloid cell-mediated inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Nuclear factor-kappaB: the enemy within

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

NF-kappaB functions as a tumour promoter in inflammation-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

NF-kappaB and cancer-identifying targets and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Opposing functions of IKKbeta during acute and chronic intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Diminished expression of transcription factors nuclear factor kappaB and CCAAT/enhancer binding protein underlies a novel tumor evasion mechanism affecting macrophages of mammary tumor-bearing mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

The immunobiology of cancer immunosurveillance and immunoediting

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

p50 Nuclear Factor- B Overexpression in Tumor-Associated Macrophages Inhibits M1 Inflammatory Responses and Antitumor Resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Identification of Biologically Active Chemokine Isoforms from Ascitic Fluid and Elevated Levels of CCL18/Pulmonary and Activation-regulated Chemokine in Ovarian Carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Macrophages promote angiogenesis in human breast tumour spheroids in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Significance of macrophage chemoattractant protein-1 expression and macrophage infiltration in squamous cell carcinoma of the esophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Refractoriness to antivascular endothelial growth factor treatment: role of myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Chemokines--chemotactic cytokines that mediate inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

CXC chemokines in angiogenesis of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Lymphatic endothelial cells, tumor lymphangiogenesis and metastasis: New insights into intratumoral and peritumoral lymphatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Microenvironmental regulation of metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-alpha dependent up-regulation of matrix metalloproteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Macrophages induce invasiveness of epithelial cancer cells via NF-kappa B and JNK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

New functions for the matrix metalloproteinases in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Matrix metalloproteinases in tumor-host cell communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Cysteine cathepsins: multifunctional enzymes in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Cysteine cathepsins and the cutting edge of cancer invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Anti-inflammatory properties of the novel antitumor agent yondelis (trabectedin): inhibition of macrophage differentiation and cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Synergy between anti-CCL2 and docetaxel as determined by DW-MRI in a metastatic bone cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Targeting CCL2 with systemic delivery of neutralizing antibodies induces prostate cancer tumor regression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Anti-VEGF-A therapy reduces lymphatic vessel density and expression of VEGFR-3 in an orthotopic breast tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Vascular endothelial growth factor receptor 2 mediates macrophage infiltration into orthotopic pancreatic tumors in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Engineering of macrophages to produce IFN-gamma in response to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Therapeutic potential of Toll-like receptor 9 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Antitumor applications of stimulating toll-like receptor 9 with CpG oligodeoxynucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Randomized phase II trial of a toll-like receptor 9 agonist oligodeoxynucleotide, PF-3512676, in combination with first-line taxane plus platinum chemotherapy for advanced-stage non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

The role of SHIP1 in macrophage programming and activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Immunological aspects of cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Immunogenic and tolerogenic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Mincle is an ITAM-coupled activating receptor that senses damaged cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0609385

21 January 2018

Identifiers

DOI

10.1189/JLB.0609385

1 reference

21 August 2017

1 reference