(Q37597933)

21 August 2017

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title

The LRRK2 G2019S mutation as the cause of Parkinson's disease in Ashkenazi Jews (English)

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21 August 2017

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3

Ziv Gan-Or

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21 August 2017

5

Nir Giladi

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21 August 2017

4

Avi Orr-Urtreger

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21 August 2017

2

Elissa Ash

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21 August 2017

1

Avner Thaler

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PubMed ID

19756366

21 August 2017

language of work or name

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1 November 2009

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Journal of Neural Transmission

21 August 2017

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21 August 2017

116

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21 August 2017

1473-1482

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21 August 2017

11

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https://scigraph.springernature.com/pub.10.1007/s00702-009-0303-0

21 August 2017

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cites work

Prevalence and clinical features of LRRK2 mutations in patients with Parkinson's disease in southern Spain.

1 reference

12 December 2020

Age estimate of the N370S mutation causing Gaucher disease in Ashkenazi Jews and European populations: A reappraisal of haplotype data

1 reference

12 December 2020

Prevalence of the LRRK2 G2019S mutation in a UK community based idiopathic Parkinson's disease cohort.

1 reference

12 December 2020

Leucine-rich repeat kinase 2 mutations and Parkinson's disease: three questions

1 reference

12 December 2020

Absence/rarity of commonly reported LRRK2 mutations in Indian Parkinson's disease patients.

1 reference

12 December 2020

LRRK2 gene G2019S mutation and SNPs [haplotypes] in subtypes of Parkinson's disease

1 reference

12 December 2020

Genetics of Parkinson's disease: LRRK2 on the rise

1 reference

12 December 2020

Is the common LRRK2 G2019S mutation related to dyskinesias in North African Parkinson disease?

1 reference

12 December 2020

Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase

1 reference

12 December 2020

LRRK2 mutations on Crete: R1441H associated with PD evolving to PSP.

1 reference

12 December 2020

Screening for Lrrk2 G2019S and clinical comparison of Tunisian and North American Caucasian Parkinson's disease families

1 reference

12 December 2020

Leucine-rich repeat kinase 2 (LRRK2): a key player in the pathogenesis of Parkinson's disease

1 reference

12 December 2020

The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation

1 reference

12 December 2020

LRRK2 G2019S is a common mutation in Spanish patients with late-onset Parkinson's disease

1 reference

12 December 2020

Contrasting patterns of Y chromosome variation in Ashkenazi Jewish and host non-Jewish European populations

1 reference

12 December 2020

Genetic analysis for five LRRK2 mutations in a Sardinian parkinsonian population: importance of G2019S and R1441C mutations in sporadic Parkinson's disease patients.

1 reference

12 December 2020

LRRK2 and neurodegeneration

1 reference

12 December 2020

Comprehensive screening of a North American Parkinson's disease cohort for LRRK2 mutation.

1 reference

12 December 2020

A founding LRRK2 haplotype shared by Tunisian, US, European and Middle Eastern families with Parkinson's disease

1 reference

12 December 2020

Genetic analysis of LRRK2 mutations in patients with Parkinson disease

1 reference

12 December 2020

LRRK2 in Parkinson's disease and dementia with Lewy bodies

1 reference

12 December 2020

Lrrk2 and Lewy body disease

1 reference

12 December 2020

The G2019S LRRK2 mutation is rare in Korean patients with Parkinson's disease.

1 reference

12 December 2020

A study of LRRK2 mutations and Parkinson's disease in Brazil

1 reference

12 December 2020

Screening for the LRRK2 G2019S and codon-1441 mutations in a pathological series of parkinsonian syndromes and frontotemporal lobar degeneration

1 reference

12 December 2020

Corticobasal syndrome and primary progressive aphasia as manifestations of LRRK2 gene mutations

1 reference

12 December 2020

Identification and haplotype analysis of LRRK2 G2019S in Japanese patients with Parkinson disease

1 reference

12 December 2020

Lrrk2 mutations in South America: A study of Chilean Parkinson's disease

1 reference

12 December 2020

Deciphering the role of heterozygous mutations in genes associated with parkinsonism

1 reference

12 December 2020

A common LRRK2 mutation in idiopathic Parkinson's disease

1 reference

12 December 2020

A clinic-based screening of mutations in exons 31, 34, 35, 41, and 48 of LRRK2 in Iranian Parkinson's disease patients.

1 reference

12 December 2020

LRRK2 G2019S mutation and Parkinson's disease: a clinical, neuropsychological and neuropsychiatric study in a large Italian sample

1 reference

12 December 2020

Validity and Utility of a LRRK2 G2019S Mutation Test for the Diagnosis of Parkinson's Disease

1 reference

12 December 2020

The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson's disease and originates from a common ancestor

1 reference

12 December 2020

Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies

1 reference

12 December 2020

Ashkenazi Parkinson's disease patients with the LRRK2 G2019S mutation share a common founder dating from the second to fifth centuries.

1 reference

12 December 2020

Clinical characteristics of Parkinson's disease among Jewish Ethnic groups in Israel

1 reference

12 December 2020

The familial Parkinsonism gene LRRK2 regulates neurite process morphology

1 reference

12 December 2020

LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews.

1 reference

12 December 2020

The prevalence of the G2019S and R1441C/G/H mutations in LRRK2 in German patients with Parkinson's disease

1 reference

12 December 2020

LRRK2 mutations are a common cause of Parkinson's disease in Spain

1 reference

12 December 2020

Increased frequency of the LRRK2 G2019S mutation in an elderly Ashkenazi Jewish population is not associated with dementia

1 reference

12 December 2020

Leucine-rich repeat kinase 2 (LRRK2) mutations in a Swedish Parkinson cohort and a healthy nonagenarian

1 reference

12 December 2020

LRRK2 G2019S in families with Parkinson disease who originated from Europe and the Middle East: evidence of two distinct founding events beginning two millennia ago.

1 reference

12 December 2020

Lrrk2 pathogenic substitutions in Parkinson's disease

1 reference

12 December 2020

Update on the functional biology of Lrrk2.

1 reference

12 December 2020

LRRK2 haplotype analyses in European and North African families with Parkinson disease: a common founder for the G2019S mutation dating from the 13th century

1 reference

12 December 2020

PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation

1 reference

12 December 2020

Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations

1 reference

12 December 2020

Clinical features of LRRK2-associated Parkinson's disease in central Norway

1 reference

12 December 2020

Genetic and clinical identification of Parkinson's disease patients with LRRK2 G2019S mutation

1 reference

12 December 2020

Hyposmia in G2019S LRRK2-related parkinsonism: clinical and pathologic data.

1 reference

12 December 2020

Clinical traits of LRRK2-associated Parkinson's disease in Ireland: a link between familial and idiopathic PD.

1 reference

12 December 2020

Frequency and phenotypes of LRRK2 G2019S mutation in Italian patients with Parkinson's disease

1 reference

12 December 2020

LRRK2 mutation in familial Parkinson’s disease in a Taiwanese population: clinical, PET, and functional studies

1 reference

12 December 2020

Evaluation of LRRK2 G2019S penetrance: Relevance for genetic counseling in Parkinson disease

1 reference

12 December 2020

Parkinson's disease and LRRK2: frequency of a common mutation in U.S. movement disorder clinics

1 reference

12 December 2020

LRRK2 mutations in Parkinson disease

1 reference

12 December 2020

Parkinson disease in twins: an etiologic study

1 reference

12 December 2020

Genetic screening for LRRK2 gene G2019S mutation in Parkinson's disease patients from Southern Italy

1 reference

12 December 2020

The G2019S LRRK2 mutation in Brazilian patients with Parkinson's disease: phenotype in monozygotic twins

1 reference

12 December 2020

Progression of dopaminergic dysfunction in a LRRK2 kindred: a multitracer PET study

1 reference

12 December 2020

LRRK2 mutations in patients with Parkinson's disease from Peru and Uruguay

1 reference

12 December 2020

LRRK2G2019S as a Cause of Parkinson's Disease in North African Arabs

1 reference

12 December 2020

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

1 reference

12 December 2020

LRRK2 low-penetrance mutations (Gly2019Ser) and risk alleles (Gly2385Arg)-linking familial and sporadic Parkinson's disease

1 reference

12 December 2020

Genetic screening of the G2019S mutation of the LRRK2 gene in Southwest European, North African, and Sephardic Jewish subjects

1 reference

12 December 2020

The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study

1 reference

12 December 2020

A common leucine-rich repeat kinase 2 gene mutation in familial and sporadic Parkinson's disease in Russia

1 reference

12 December 2020

Prevalence and clinical features of common LRRK2 mutations in Australians with Parkinson's disease.

1 reference

12 December 2020

LRRK2 and GBA mutations differentially affect the initial presentation of Parkinson disease.

1 reference

12 December 2020

Striatal dopamine transporter binding in Parkinson's disease associated with the LRRK2 Gly2019Ser mutation.

1 reference

12 December 2020

Analysis of LRRK2 G2019S and I2020T mutations in Parkinson's disease

1 reference

12 December 2020

The leucine rich repeat kinase 2 (LRRK2) G2019S substitution mutation. Association with Parkinson disease, malignant melanoma and prevalence in ethnic groups in Israel.

1 reference

12 December 2020

LRRK2 is not a significant cause of Parkinson's disease in French-Canadians

1 reference

12 December 2020

Frequency of the LRRK2 G2019S mutation in Italian patients affected by Parkinson's disease.

1 reference

12 December 2020

Clinicogenetic study of mutations inLRRK2 exon 41 in Parkinson's disease patients from 18 countries

1 reference

12 December 2020

Genetics of Parkinson's disease and parkinsonism

1 reference

12 December 2020

The G2019S LRRK2 mutation is uncommon amongst Greek patients with sporadic Parkinson's disease

1 reference

12 December 2020

G2019S LRRK2 mutation in French and North African families with Parkinson's disease

1 reference

12 December 2020

Parkinsonism, Lrrk2 G2019S, and tau neuropathology

1 reference

12 December 2020

LRRK2 mutations in Spanish patients with Parkinson disease: frequency, clinical features, and incomplete penetrance

1 reference

12 December 2020

Clinical Heterogeneity of the LRRK2 G2019S Mutation

1 reference

12 December 2020

A clinic-based study of the LRRK2 gene in Parkinson disease yields new mutations

1 reference

12 December 2020

Parkinson disease, 10 years after its genetic revolution: multiple clues to a complex disorder

1 reference

12 December 2020

LRRK2 G2019S and R1441G mutations associated with Parkinson's disease are common in the Basque Country, but relative prevalence is determined by ethnicity.

1 reference

12 December 2020

High prevalence of LRRK2 mutations in familial and sporadic Parkinson's disease in Portugal

1 reference

12 December 2020

Screening for LRRK2 mutations in patients with Parkinson's disease in Russia: identification of a novel LRRK2 variant

1 reference

12 December 2020

Contribution of somal Lewy bodies to neuronal death.

1 reference

12 December 2020

Genetic screening for two LRRK2 mutations in French patients with idiopathic Parkinson's disease

1 reference

12 December 2020

LRRK2 expression in normal and pathologic human brain and in human cell lines

1 reference

12 December 2020

Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

1 reference

12 December 2020

Frequency of LRRK2 mutations in early- and late-onset Parkinson disease.

1 reference

12 December 2020

The G2019S LRRK2 mutation is uncommon in an Asian cohort of Parkinson's disease patients.

1 reference

12 December 2020

G2019S LRRK2 mutation in familial and sporadic Parkinson's disease in Russia

1 reference

12 December 2020

The LRRK2 G2019S mutation in Ashkenazi Jews with Parkinson disease: is there a gender effect?

1 reference

12 December 2020

Is the G2019S LRRK2 mutation common in all southern European populations?

1 reference

12 December 2020

Clinical features of Parkinson disease patients with homozygous leucine-rich repeat kinase 2 G2019S mutations.

1 reference

12 December 2020

G2019S dardarin substitution is a common cause of Parkinson's disease in a Portuguese cohort

1 reference

12 December 2020

LRRK2 Gly2019Ser penetrance in Arab-Berber patients from Tunisia: a case-control genetic study

1 reference

12 December 2020

Genotype-phenotype correlations between GBA mutations and Parkinson disease risk and onset

1 reference

12 December 2020

Molecular biology changes associated with LRRK2 mutations in Parkinson's disease

1 reference

12 December 2020

Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data

1 reference

12 December 2020

Roc, a Ras/GTPase domain in complex proteins

1 reference

12 December 2020

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

1 reference

12 December 2020

Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease

1 reference

12 December 2020

10.1007/S00702-009-0303-0

Identifiers

DOI

1 reference

21 August 2017

1 reference

PubMed ID

19756366