(Q37598261)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19758107%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

review article

1 reference

title

Histamine H3 and H4 receptors as novel drug targets (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19758107%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19758107%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

author name string

Ekaterini Tiligada

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19758107%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Kerstin Sander

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19758107%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Holger Stark

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19758107%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

language of work or name

English

0 references

publication date

1 October 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19758107%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Investigational Drugs

7 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19758107%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19758107%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19758107%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

page(s)

1519-1531

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19758107%20AND%20SRC:MED&resulttype=core&format=json

Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist

7 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

A detailed autoradiographic mapping of histamine H3 receptors in rat brain areas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Constitutive activity of the histamine H3 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histamine H3 receptor antagonists go to clinics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Cloning and characterization of the monkey histamine H3 receptor isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histamine H3-receptor isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histamine function in brain disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

The role of histamine on cognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Acetylcholine, histamine, and cognition: two sides of the same coin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Interactions between histaminergic and cholinergic systems in learning and memory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histamine H3 receptor antagonists: from target identification to drug leads

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histamine H3 and dopamine D2 receptor-mediated [35S]GTPgamma[S] binding in rat striatum: evidence for additive effects but lack of interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Interactions between histamine H3 and dopamine D2 receptors and the implications for striatal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Altered histamine H3 receptor radioligand binding in post-mortem brain samples from subjects with psychiatric diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Dopamine and serotonin interactions in the prefrontal cortex: insights on antipsychotic drugs and their mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Preclinical investigations into the antipsychotic potential of the novel histamine H3 receptor antagonist GSK207040.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Brain histamine and schizophrenia: potential therapeutic applications of H3-receptor inverse agonists studied with BF2.649.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Potential utility of histamine H3 receptor antagonist pharmacophore in antipsychotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histamine H3-receptor inverse agonists as novel antipsychotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

The mechanism of spontaneous firing in histamine neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

From waking to sleeping: neuronal and chemical substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histamine action on vertebrate GABAA receptors: direct channel gating and potentiation of GABA responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Orexin A promotes histamine, but not norepinephrine or serotonin, release in frontal cortex of mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Arousal effect of orexin A depends on activation of the histaminergic system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

GABAB-receptor-mediated control of GABAergic inhibition in rat histaminergic neurons in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Narcolepsy with cataplexy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Cataplexy-active neurons in the hypothalamus: implications for the role of histamine in sleep and waking behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

The brain H3-receptor as a novel therapeutic target for vigilance and sleep-wake disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Differential effects of acute and repeat dosing with the H3 antagonist GSK189254 on the sleep-wake cycle and narcoleptic episodes in Ox-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

An inverse agonist of the histamine H(3) receptor improves wakefulness in narcolepsy: studies in orexin-/- mice and patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

BF2.649 [1-{3-[3-(4-Chlorophenyl)propoxy]propyl}piperidine, hydrochloride], a nonimidazole inverse agonist/antagonist at the human histamine H3 receptor: Preclinical pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Kindling and status epilepticus models of epilepsy: rewiring the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Is histamine an anticonvulsive inhibitory transmitter?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histaminergic mechanisms in amygdaloid-kindled seizures in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

The histamine H3 receptor antagonist clobenpropit enhances GABA release to protect against NMDA-induced excitotoxicity through the cAMP/protein kinase A pathway in cultured cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Role of histaminergic neurons in development of epileptic seizures in EL mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histamine and selective H3-receptor ligands: a possible role in the mechanism and management of epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histamine-induced itch converts into pain in neuropathic hyperalgesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Immune and inflammatory mechanisms in neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Chemokines and the pathophysiology of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Novel histamine H3 receptor antagonists GSK189254 and GSK334429 are efficacious in surgically-induced and virally-induced rat models of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Immunohistochemical localization of histamine H3 receptors in rodent skin, dorsal root ganglia, superior cervical ganglia, and spinal cord: potential antinociceptive targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Activation of spinal histamine H3 receptors inhibits mechanical nociception

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Role of histamine H3 and H4 receptors in mechanical hyperalgesia following peripheral nerve injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Rodent antinociception following acute treatment with different histamine receptor agonists and antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Antiinflammatory and antinociceptive effects of the selective histamine H4-receptor antagonists JNJ7777120 and VUF6002 in a rat model of carrageenan-induced acute inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Rotationally constrained 2,4-diamino-5,6-disubstituted pyrimidines: a new class of histamine H4 receptor antagonists with improved druglikeness and in vivo efficacy in pain and inflammation models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

The role of histamine H4 receptor in immune and inflammatory disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Molecular and biochemical pharmacology of the histamine H4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

The first potent and selective non-imidazole human histamine H4 receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Discovery of novel human histamine H4 receptor ligands by large-scale structure-based virtual screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Homology model adjustment and ligand screening with a pseudoreceptor of the human histamine H4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

N(G)-acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Identification of a histamine H4 receptor on human eosinophils--role in eosinophil chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histamine 4 receptor activation induces recruitment of FoxP3+ T cells and inhibits allergic asthma in a murine model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

The histamine H4 receptor antagonist JNJ7777120 induces increases in the histamine content of the rat conjunctiva

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Antigen inhalation induces mast cells and eosinophils infiltration in the guinea pig esophageal epithelium involving histamine-mediated pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in Balb C mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histamine H4 receptors modulate dendritic cell migration through skin--immunomodulatory role of histamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histamine H4 receptor antagonism reduces hapten-induced scratching behaviour but not inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histamine H4 receptor expression in human synovial cells obtained from patients suffering from rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Expression of histamine H4 receptor in synovial cells from rheumatoid arthritic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Expression of histamine H4 receptor in human osteoarthritic synovial tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Decreased expression of histamine H1 and H4 receptors suggests disturbance of local regulation in human colorectal tumours by histamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Histamine-mediated signaling processes in human malignant mammary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

The role of histamine in human mammary carcinogenesis: H3 and H4 receptors as potential therapeutic targets for breast cancer treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438

Autoregulation of McA-RH7777 hepatoma cell proliferation by histamine H3 receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903188438