(Q37598949)

21 August 2017

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title

Tumor immunosuppressive environment: effects on tumor-specific and nontumor antigen immune responses (English)

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21 August 2017

Ana Paula de Souza

1

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21 August 2017

Cristina Bonorino

series ordinal

2

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21 August 2017

publication date

1 September 2009

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Expert Review of Anticancer Therapy

21 August 2017

published in

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21 August 2017

volume

9

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21 August 2017

issue

9

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21 August 2017

page(s)

1317-1332

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21 August 2017

cites work

The Hallmarks of Cancer

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Tumor Development after 3-Methylcholanthrene in Immunologically Deficient Athymic-Nude Mice

21 January 2018

1 reference

Cancer immunoediting: from immunosurveillance to tumor escape

21 January 2018

1 reference

A fresh look at tumor immunosurveillance and immunotherapy.

21 January 2018

1 reference

Does the immune system see tumors as foreign or self?

21 January 2018

1 reference

IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity

21 January 2018

1 reference

Interferons, immunity and cancer immunoediting

21 January 2018

1 reference

Cancer immunosurveillance, immunoediting and inflammation: independent or interdependent processes?

21 January 2018

1 reference

How tumours escape mass destruction

21 January 2018

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Immunosuppressive networks in the tumour environment and their therapeutic relevance

21 January 2018

1 reference

Tumour-induced immune modulation of sentinel lymph nodes

21 January 2018

1 reference

Type 1 T regulatory cells.

21 January 2018

1 reference

Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells

21 January 2018

1 reference

Gangliosides from human melanoma tumors impair dendritic cell differentiation from monocytes and induce their apoptosis

21 January 2018

1 reference

Different mechanisms are involved in apoptosis induced by melanoma gangliosides on human monocyte-derived dendritic cells

21 January 2018

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Dendritic cells and the control of immunity

21 January 2018

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Immunobiology of dendritic cells

21 January 2018

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Mechanisms and functional significance of tumour-induced dendritic-cell defects

21 January 2018

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Angiogenesis in cancer and other diseases

21 January 2018

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Differentiation of T regulatory cells by immature dendritic cells

21 January 2018

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Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells

21 January 2018

1 reference

Transforming growth factor-beta regulation of immune responses

21 January 2018

1 reference

TGF-beta: a mobile purveyor of immune privilege

21 January 2018

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Tumor progression can occur despite the induction of very high levels of self/tumor antigen-specific CD8+ T cells in patients with melanoma

21 January 2018

1 reference

Evolving immunosuppressive microenvironment during human cervical carcinogenesis

21 January 2018

1 reference

Characterization of the antibody response against NeuGcGM3 ganglioside elicited in non-small cell lung cancer patients immunized with an anti-idiotype antibody

21 January 2018

1 reference

Recognition of tumor glycans by antigen-presenting cells

21 January 2018

1 reference

MUC1 immunobiology: from discovery to clinical applications

21 January 2018

1 reference

Induction of a CD4+ T regulatory type 1 response by cyclooxygenase-2-overexpressing glioma

21 January 2018

1 reference

High expression of PGE2 enzymatic pathways in cervical (pre)neoplastic lesions and functional consequences for antigen-presenting cells

21 January 2018

1 reference

Dendritic cells are functionally defective in multiple myeloma: the role of interleukin-6.

21 January 2018

1 reference

Cyclooxygenase-2 induces genomic instability, BCL2 expression, doxorubicin resistance, and altered cancer-initiating cell phenotype in MCF7 breast cancer cells

21 January 2018

1 reference

21 January 2018

Inflammation and cancer

1 reference

Prostanoids play a major role in the primary tumor-induced inhibition of dendritic cell differentiation

21 January 2018

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Prostaglandins as modulators of immunity

21 January 2018

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IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation.

21 January 2018

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T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

21 January 2018

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Induction and effector functions of T(H)17 cells.

21 January 2018

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IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

21 January 2018

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Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

21 January 2018

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Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase

21 January 2018

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Gr-1+ myeloid cells derived from tumor-bearing mice inhibit primary T cell activation induced through CD3/CD28 costimulation

21 January 2018

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Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism.

21 January 2018

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Role of immature myeloid cells in mechanisms of immune evasion in cancer

21 January 2018

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High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells

21 January 2018

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Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma

21 January 2018

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Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma

21 January 2018

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Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion

21 January 2018

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L-arginine consumption by macrophages modulates the expression of CD3 zeta chain in T lymphocytes

21 January 2018

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Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence.

21 January 2018

1 reference

Tumor-educated CD11bhighIalow regulatory dendritic cells suppress T cell response through arginase I.

21 January 2018

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Regulation of immune responses by L-arginine metabolism

21 January 2018

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Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

21 January 2018

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Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells

21 January 2018

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Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells

21 January 2018

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Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation

21 January 2018

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The dynamic co-evolution of memory and regulatory CD4+ T cells in the periphery

21 January 2018

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Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

21 January 2018

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Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

21 January 2018

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Natural regulatory T cells: mechanisms of suppression

21 January 2018

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Dynamic behavior and function of Foxp3+ regulatory T cells in tumor bearing host

21 January 2018

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CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1.

21 January 2018

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Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells

21 January 2018

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Immunoregulatory T cells in tumor immunity

21 January 2018

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Enhanced formation and survival of CD4+ CD25hi Foxp3+ T-cells in chronic lymphocytic leukemia.

21 January 2018

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Regulatory T-cell-mediated attenuation of T-cell responses to the NY-ESO-1 ISCOMATRIX vaccine in patients with advanced malignant melanoma

21 January 2018

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OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection

21 January 2018

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CD8+ Foxp3+ regulatory T cells mediate immunosuppression in prostate cancer

21 January 2018

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Expression of indoleamine 2,3-dioxygenase in metastatic malignant melanoma recruits regulatory T cells to avoid immune detection and affects survival.

21 January 2018

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High expression of indoleamine 2,3-dioxygenase gene in prostate cancer

21 January 2018

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Expression of indoleamine 2,3-dioxygenase in metastatic pancreatic ductal adenocarcinoma recruits regulatory T cells to avoid immune detection

21 January 2018

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Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

21 January 2018

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Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

21 January 2018

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Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells: mediation of suppression by tryptophan metabolites

21 January 2018

1 reference

Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasion

21 January 2018

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Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

21 January 2018

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PD-L2 is a second ligand for PD-1 and inhibits T cell activation

21 January 2018

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Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer

21 January 2018

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Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up.

21 January 2018

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PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients

21 January 2018

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Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade

21 January 2018

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B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

21 January 2018

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Cutting edge: induction of B7-H4 on APCs through IL-10: novel suppressive mode for regulatory T cells

21 January 2018

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Immune signatures of murine and human cancers reveal unique mechanisms of tumor escape and new targets for cancer immunotherapy.

21 January 2018

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The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses

21 January 2018

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Expression and regulation of non-classical HLA-G in renal cell carcinoma

21 January 2018

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Galectins as modulators of tumour progression

21 January 2018

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Apoptosis of T cells mediated by galectin-1.

21 January 2018

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Galectin-1 induces partial TCR zeta-chain phosphorylation and antagonizes processive TCR signal transduction

21 January 2018

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Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles.

21 January 2018

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Human tumor-released microvesicles promote the differentiation of myeloid cells with transforming growth factor-beta-mediated suppressive activity on T lymphocytes

21 January 2018

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Altered NKG2D function in NK cells induced by chronic exposure to NKG2D ligand-expressing tumor cells

21 January 2018

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NKG2D function protects the host from tumor initiation

21 January 2018

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Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance

21 January 2018

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The STATs of cancer--new molecular targets come of age

21 January 2018

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Roles of activated Src and Stat3 signaling in melanoma tumor cell growth

21 January 2018

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Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity

21 January 2018

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IL-23 promotes tumour incidence and growth

21 January 2018

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Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment

21 January 2018

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SOCS1 restricts dendritic cells' ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling

21 January 2018

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The hypoxic microenvironment of the skin contributes to Akt-mediated melanocyte transformation.

21 January 2018

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Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cells

21 January 2018

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The role of Fas/FasL in immunosuppression induced by human tumors

21 January 2018

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T-cell receptor signal transmission: who gives an ITAM?

21 January 2018

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Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

21 January 2018

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A spontaneously arising pancreatic tumor does not promote the differentiation of naive CD8+ T lymphocytes into effector CTL.

21 January 2018

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Induction of antigen-specific T cell anergy: An early event in the course of tumor progression

21 January 2018

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In vivo disruption of tolerogenic cross-presentation mechanisms uncovers an effective T-cell activation by B-cell lymphomas leading to antitumor immunity

21 January 2018

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Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen

21 January 2018

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Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

21 January 2018

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Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes

21 January 2018

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Decreased absolute counts of T lymphocyte subsets and their relation to disease in squamous cell carcinoma of the head and neck

21 January 2018

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Evidence of systemic Th2-driven chronic inflammation in patients with metastatic melanoma

21 January 2018

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Lymphocyte composition of tumor draining lymph nodes from cervical and endometrial cancer patients

21 January 2018

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In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas.

21 January 2018

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Analysis of dendritic cells in tumor-free and tumor-containing sentinel lymph nodes from patients with breast cancer

21 January 2018

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Defective MHC class II presentation by dendritic cells limits CD4 T cell help for antitumor CD8 T cell responses

21 January 2018

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Clinical responsiveness of glioblastoma multiforme to chemotherapy after vaccination

21 January 2018

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Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma.

21 January 2018

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The anticancer immune response: indispensable for therapeutic success?

21 January 2018

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Inhibition of TGFbeta signaling in cancer therapy

21 January 2018

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Development of TGF-beta signalling inhibitors for cancer therapy

21 January 2018

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Stat3 activity in melanoma cells affects migration of immune effector cells and nitric oxide-mediated antitumor effects

21 January 2018

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Synergy between tumor immunotherapy and antiangiogenic therapy

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/ERA.09.88

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21 August 2017

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