(Q37601736)

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CaMKII Phosphorylation of Na(V)1.5: Novel in Vitro Sites Identified by Mass Spectrometry and Reduced S516 Phosphorylation in Human Heart Failure

scientific article published on 13 April 2015

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Europe PubMed Central

PMC publication ID

21 August 2017

CaMKII Phosphorylation of Na(V)1.5: Novel in Vitro Sites Identified by Mass Spectrometry and Reduced S516 Phosphorylation in Human Heart Failure (English)

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Europe PubMed Central

PMC publication ID

21 August 2017

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phosphorylation

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Brett S. Phinney

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25815641%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

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7 June 2020

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Anthony W Herren

1

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7 June 2020

Darren M Weber

2

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7 June 2020

Robert R Rigor

3

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7 June 2020

Kenneth B Margulies

4

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7 June 2020

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13 April 2015

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21 August 2017

Journal of Proteome Research

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7 June 2020

14

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Europe PubMed Central

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7 June 2020

5

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Europe PubMed Central

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7 June 2020

2298-2311

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Europe PubMed Central

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7 June 2020

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11 June 2022

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based on heuristic

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mass spectrometry

1 reference

based on heuristic

inferred from title

Reciprocal changes in phosphorylation and methylation of mammalian brain sodium channels in response to seizures

1 reference

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23 August 2017

Ankyrin-G participates in INa remodeling in myocytes from the border zones of infarcted canine heart

1 reference

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23 August 2017

PKCα-specific phosphorylation of the troponin complex in human myocardium: a functional and proteomics analysis

1 reference

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23 August 2017

Protein arginine methyl transferases-3 and -5 increase cell surface expression of cardiac sodium channel

1 reference

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23 August 2017

Post-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of -Adrenergic Receptor Signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Characterization of the cardiac myosin binding protein-C phosphoproteome in healthy and failing human hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease

1 reference

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23 August 2017

Molecular mechanisms underlying cardiac protein phosphatase 2A regulation in heart

1 reference

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23 August 2017

Mass spectrometry-based identification of native cardiac Nav1.5 channel α subunit phosphorylation sites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Ca2+/calmodulin-dependent protein kinase II-based regulation of voltage-gated Na+ channel in cardiac disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Prediction of functional phosphorylation sites by incorporating evolutionary information

1 reference

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23 August 2017

Dominant-negative effect of SCN5A N-terminal mutations through the interaction of Na(v)1.5 α-subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Blocking Scn10a channels in heart reduces late sodium current and is antiarrhythmic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Identifying protein kinase target preferences using mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

PKCε phosphorylation of the sodium channel NaV1.8 increases channel function and produces mechanical hyperalgesia in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Phosphorylation and activation of the plasma membrane Na+/H+ exchanger (NHE1) during osmotic cell shrinkage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Deciphering the Arginine-binding preferences at the substrate-binding groove of Ser/Thr kinases by computational surface mapping

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

The cardiac sodium channel is post-translationally modified by arginine methylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Identification of CaMKII phosphorylation sites in Connexin43 by high-resolution mass spectrometry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Multisite phosphorylation of voltage-gated sodium channel alpha subunits from rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Cardiac sodium channel Na(v)1.5 and interacting proteins: Physiology and pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Pathophysiology and pharmacology of the cardiac "late sodium current.".

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Cardiac sodium channel overlap syndromes: different faces of SCN5A mutations

1 reference

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23 August 2017

Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

A probability-based approach for high-throughput protein phosphorylation analysis and site localization

1 reference

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M-Coffee: combining multiple sequence alignment methods with T-Coffee

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23 August 2017

Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase.

1 reference

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23 August 2017

A statistical model for identifying proteins by tandem mass spectrometry

1 reference

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23 August 2017

The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure

1 reference

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23 August 2017

Phosphorylation of S1505 in the cardiac Na+ channel inactivation gate is required for modulation by protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

23 August 2017

Protein kinase phosphorylation site sequences and consensus specificity motifs: tabulations

1 reference

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CaMKII inhibitors: from research tools to therapeutic agents

1 reference

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6 September 2017

Function and regulation of serine/threonine phosphatases in the healthy and diseased heart.

1 reference

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6 September 2017

About half of the late sodium current in cardiac myocytes from dog ventricle is due to non-cardiac-type Na(+) channels

1 reference

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6 September 2017

Phenotypical manifestations of mutations in the genes encoding subunits of the cardiac sodium channel

1 reference

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6 September 2017

CaMKII in myocardial hypertrophy and heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

6 September 2017

Mass spectrometry-based phosphoproteomics reveals multisite phosphorylation on mammalian brain voltage-gated sodium and potassium channels

1 reference

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6 September 2017

ERK1/2 mitogen-activated protein kinase phosphorylates sodium channel Na(v)1.7 and alters its gating properties

1 reference

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14 September 2017

Graded regulation of the Kv2.1 potassium channel by variable phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

14 September 2017

Interplay between R513 methylation and S516 phosphorylation of the cardiac voltage-gated sodium channel.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

25 June 2018

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1 reference

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25 June 2018

cAMP-dependent phosphorylation of two sites in the alpha subunit of the cardiac sodium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

25 June 2018

Protein folding creates structure-based, noncontiguous consensus phosphorylation motifs recognized by kinases.

1 reference

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1 September 2018

Phospholemman-dependent regulation of the cardiac Na/K-ATPase activity is modulated by inhibitor-1 sensitive type-1 phosphatase

1 reference

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1 September 2018

Inhibition of Elevated Ca 2+ /Calmodulin-Dependent Protein Kinase II Improves Contractility in Human Failing Myocardium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

1 September 2018

Weak functional constraints on phosphoproteomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

1 September 2018

Phosphorylation of sodium channel Na(v)1.8 by p38 mitogen-activated protein kinase increases current density in dorsal root ganglion neurons

1 reference

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1 September 2018

Increased late sodium current in myocytes from a canine heart failure model and from failing human heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

1 September 2018

Connexin 43 downregulation and dephosphorylation in nonischemic heart failure is associated with enhanced colocalized protein phosphatase type 2A.

1 reference

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1 September 2018

Identification of N-terminal protein acetylation and arginine methylation of the voltage-gated sodium channel in end-stage heart failure human heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5259567

3 December 2018

Two distinct congenital arrhythmias evoked by a multidysfunctional Na(+) channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/25815641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phosphorylation site in the Na+ channel required for modulation by protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/25815641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/25815641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/ACS.JPROTEOME.5B00107

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25815641%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25815641%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25815641%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

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