(Q24315218)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

0 references

0 references

Calcium/calmodulin dependent protein kinase II delta

1 reference

Sodium voltage-gated channel alpha subunit 5

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

protein kinase binding

1 reference

GOA release 2020-03-11

author

Donald M. Bers

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

6

Theodore R Cummins

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

2

Anthony W Herren

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Nicole M Ashpole

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Kenneth S Ginsburg

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Joseph D Brogan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Derrick E Johnson

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Andy Hudmon

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

language of work or name

English

0 references

publication date

18 April 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

29 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

287

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

19856-19869

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5

29 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

CaMKII tethers to L-type Ca2+ channels, establishing a local and dedicated integrator of Ca2+ signals for facilitation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

A calcium sensor in the sodium channel modulates cardiac excitability

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

The sodium channel beta-subunit SCN3b modulates the kinetics of SCN5a and is expressed heterogeneously in sheep heart

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Control of transient, resurgent, and persistent current by open-channel block by Na channel beta4 in cultured cerebellar granule neurons

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Differential regulated interactions of calcium/calmodulin-dependent protein kinase II with isoforms of voltage-gated calcium channel beta subunits

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Identification and expression of delta-isoforms of the multifunctional Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human myocardium

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Signaling through scaffold, anchoring, and adaptor proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Post-transcriptional silencing of SCN1B and SCN2B genes modulates late sodium current in cardiac myocytes from normal dogs and dogs with chronic heart failure

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

CaMKII in myocardial hypertrophy and heart failure

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

CaMKII regulation of voltage-gated sodium channels and cell excitability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Na+ channel regulation by Ca2+/calmodulin and Ca2+/calmodulin-dependent protein kinase II in guinea-pig ventricular myocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Sodium channel mutations and arrhythmias

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Late Na+ current produced by human cardiac Na+ channel isoform Nav1.5 is modulated by its beta1 subunit.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Calcium/calmodulin-dependent kinase II regulation of cardiac ion channels

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Regulation of persistent Na current by interactions between beta subunits of voltage-gated Na channels

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Modulation of late sodium current by Ca2+, calmodulin, and CaMKII in normal and failing dog cardiomyocytes: similarities and differences

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Roles and regulation of the cardiac sodium channel Na v 1.5: recent insights from experimental studies.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

CaMKII, an emerging molecular driver for calcium homeostasis, arrhythmias, and cardiac dysfunction.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Graded regulation of the Kv2.1 potassium channel by variable phosphorylation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Calcium-dependent regulation of the voltage-gated sodium channel hH1: intrinsic and extrinsic sensors use a common molecular switch

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Calcium/calmodulin-dependent protein kinase II (CaMKII) localization acts in concert with substrate targeting to create spatial restriction for phosphorylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Modulation of Na(v)1.5 by beta1-- and beta3-subunit co-expression in mammalian cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Calmodulin mediates Ca2+ sensitivity of sodium channels

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

An EF-hand in the sodium channel couples intracellular calcium to cardiac excitability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Mechanisms of sodium channel inactivation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Immobilized peptides as high-affinity capture agents for self-associating proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Functional modulation of human brain Nav1.3 sodium channels, expressed in mammalian cells, by auxiliary beta 1, beta 2 and beta 3 subunits

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

The SPOT-synthesis technique. Synthetic peptide arrays on membrane supports--principles and applications

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Isoform-specific modulation of voltage-gated Na(+) channels by calmodulin.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Interaction with the NMDA receptor locks CaMKII in an active conformation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Activity of cAMP-dependent protein kinase and Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human hearts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370170

Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure

30 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.322537

Chemical quenched flow kinetic studies indicate an intraholoenzyme autophosphorylation mechanism for Ca2+/calmodulin-dependent protein kinase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.322537

Excitotoxic neuroprotection and vulnerability with CaMKII inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.322537

Phosphorylation of sodium channel Na(v)1.8 by p38 mitogen-activated protein kinase increases current density in dorsal root ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.322537

Autophosphorylation-dependent targeting of calcium/ calmodulin-dependent protein kinase II by the NR2B subunit of the N-methyl- D-aspartate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.322537

Differential modulation of sodium channel gating and persistent sodium currents by the beta1, beta2, and beta3 subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.322537

Constitutive CaMKII activity regulates Na+ channel in rat ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.322537

Modulation of skeletal and cardiac voltage-gated sodium channels by calmodulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.322537

Regulatory interaction of sodium channel IQ-motif with calmodulin C-terminal lobe

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.322537

The neuronal voltage-dependent sodium channel type II IQ motif lowers the calcium affinity of the C-domain of calmodulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.322537

The sodium channel -subunit SCN3b modulates the kinetics of SCN5a and is expressed heterogeneously in sheep heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.322537

SPOT synthesis. Epitope analysis with arrays of synthetic peptides prepared on cellulose membranes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22514276

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Two distinct congenital arrhythmias evoked by a multidysfunctional Na(+) channel

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22514276

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Definition of optimal substrate recognition motifs of Ca2+-calmodulin-dependent protein kinases IV and II reveals shared and distinctive features

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22514276

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.322537

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

PubMed publication ID

22514276

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22514276%20AND%20SRC:MED&resulttype=core&format=json