(Q37611219)

21 August 2017

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title

Genotype-phenotype mapping developmental biology confronts the toolkit paradox (English)

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21 August 2017

main subject

developmental biology

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1 reference

Joel Atallah

1

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21 August 2017

Ellen Larsen

series ordinal

2

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21 August 2017

publication date

1 January 2009

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International Review of Cell and Molecular Biology

21 August 2017

published in

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21 August 2017

volume

278

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21 August 2017

page(s)

119-148

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Deletion of ultraconserved elements yields viable mice

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

How to perform meaningful estimates of genetic effects.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Adaptive evolution of non-coding DNA in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Effects of genetic and environmental factors on the a-b, b-c and c-d interdigital ridge counts

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Four twins for a paradox: on "sensitive" twins and the biological counterpart of the "twin paradox".

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

The environmental and genetic regulation of obake expressivity: morphogenetic fields as evolvable systems.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Cell dynamics and developmental bias in the ontogeny of a complex sexually dimorphic trait in Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Developmental constraints and convergent evolution in Drosophila sex comb formation.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Sex-specific expression of a HOX gene associated with rapid morphological evolution

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Genetic Control of Biochemical Reactions in Neurospora

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Ultraconserved Elements in the Human Genome

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Evolutionary capacitance as a general feature of complex gene networks

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Exploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genome

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Putting the tissue and environmental ‘context’ into differentiation and gene regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

THE BAR "GENE" A DUPLICATION

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

The long and the short of noncoding RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Creation and implications of a phenome-genome network

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Implications of the Human Genome Project for medical science.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Deletion of a 760 kb region at 4p16 determines the prenatal and postnatal growth retardation characteristic of Wolf-Hirschhorn syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Patterning of the Drosophila embryo by a homeodomain-deleted Ftz polypeptide.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Properties of developmental gene regulatory networks

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

A genomic regulatory network for development

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Stretching single talin rod molecules activates vinculin binding

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Dorsal-ventral pattern of Delta trafficking is established by a Snail-Tom-Neuralized pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

The rise and fall of Hox gene clusters

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Evidence for canalization of Distal-less function in the leg of Drosophila melanogaster.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Evidence that Egfr contributes to cryptic genetic variation for photoreceptor determination in natural populations of Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Lessons from a gene regulatory network: echinoderm skeletogenesis provides insights into evolution, plasticity and morphogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Convergent evolution of genomic imprinting in plants and mammals.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Modelling 'evo-devo' with RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Cis and trans regulatory effects contribute to natural variation in transcriptome of Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Small silencing RNAs: an expanding universe

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Uncovering cryptic genetic variation.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Cis-regulation of achaete and scute: shared enhancer-like elements drive their coexpression in proneural clusters of the imaginal discs.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Prediction of similarly acting cis-regulatory modules by subsequence profiling and comparative genomics in Drosophila melanogaster and D.pseudoobscura

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

1 reference

7 January 2021

Developmental patterning by mechanical signals in Arabidopsis

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Sepsid even-skipped enhancers are functionally conserved in Drosophila despite lack of sequence conservation

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Physical modeling of cell geometric order in an epithelial tissue

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Developmental gene regulatory network architecture across 500 million years of echinoderm evolution

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Ciona intestinalis Hox gene cluster: Its dispersed structure and residual colinear expression in development

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Initial sequencing and analysis of the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Finishing the euchromatic sequence of the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

The Genotype Conception of Heredity

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

SNP array mapping of chromosome 20p deletions: genotypes, phenotypes, and copy number variation

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Human genome ultraconserved elements are ultraselected

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Organizing axes in time and space; 25 years of colinear tinkering

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Evolution of male sexual characters in the oriental Drosophila melanogaster species group.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Nutritional control of reproductive status in honeybees via DNA methylation

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Computational identification of Drosophila microRNA genes

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Tissue strategies as developmental constraints: Implications for animal evolution.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

The morphogenetic alphabet: lessons for simple-minded genes

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Antenna to leg transformation: dynamics of developmental competence.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Gene regulatory networks for development

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

A gene complex controlling segmentation in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

The microRNAs of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Evidence for stabilizing selection in a eukaryotic enhancer element.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Osteogenesis imperfecta: mosaicism and refinement of the genotype-phenotype map in OI type III. Mutations in brief no. 242. Online

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

A mechanosensitive transcriptional mechanism that controls angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Two or four bristles: functional evolution of an enhancer of scute in Drosophilidae

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Genome-wide analysis of clustered Dorsal binding sites identifies putative target genes in the Drosophila embryo

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Patterns of cell division in imaginal discs of Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Adaptive protein evolution at the Adh locus in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Light control of seedling morphogenetic pattern

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Inferring molecular function: contributions from functional linkages

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Large-scale turnover of functional transcription factor binding sites in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Regulatory evolution in proteins by turnover and lineage-specific changes of cyclin-dependent kinase consensus sites

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Heterochronic Genes and the Nature of Developmental Time

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Ontogeny of the syndesmosis tibiofibularis and the evolution of the bird hindlimb: a caenogenetic feature triggers phenotypic novelty.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

The regulatory content of intergenic DNA shapes genome architecture

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Abundant genetic variation in transcript level during early Drosophila development

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Global regulatory logic for specification of an embryonic cell lineage

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

In vivo enhancer analysis of human conserved non-coding sequences

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Epigenetic inheritance during the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

microRNA target predictions in animals

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

How Drosophila change their combs: the Hox gene Sex combs reduced and sex comb variation among Sophophora species.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

A missing link in the sea urchin embryo gene regulatory network: hesC and the double-negative specification of micromeres.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

The Caenorhabditis elegans vulva: a post-embryonic gene regulatory network controlling organogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Reverse engineering the genotype-phenotype map with natural genetic variation

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Hox protein mutation and macroevolution of the insect body plan

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

The Drosophila microRNA iab-4 causes a dominant homeotic transformation of halteres to wings

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Birth and rapid subcellular adaptation of a hominoid-specific CDC14 protein

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Time- and concentration-dependent response of the Drosophila antenna imaginal disc to Antennapedia.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Hox cluster disintegration with persistent anteroposterior order of expression in Oikopleura dioica

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Progression of the cell cycle through mitosis leads to abortion of nascent transcripts

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Unraveling genomic regulatory networks in the simple chordate, Ciona intestinalis

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Analysis of the Tribolium homeotic complex: insights into mechanisms constraining insect Hox clusters

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Waddington's canalization revisited: developmental stability and evolution

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Computational methods for transcriptional regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Whole-genome analysis of dorsal-ventral patterning in the Drosophila embryo

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

INHERITANCE OF DIRECTION OF COILLING IN LIMNAEA

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Characterization of the Drosophila segment determination morphome.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Activation of a signaling cascade by cytoskeleton stretch

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Distinct developmental mechanisms underlie the evolutionary diversification of Drosophila sex combs.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Cell lineage and differentiation on the male foreleg of Drosophila melanogaster.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Directed movements and selective adhesion of embryonic amphibian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

A regulatory module embedded in the coding region of Hoxa2 controls expression in rhombomere 2

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Redundant mechanisms mediate bristle patterning on the Drosophila thorax

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Local force and geometry sensing regulate cell functions

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Design and constraints of the Drosophila segment polarity module: robust spatial patterning emerges from intertwined cell state switches.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

The segment polarity network is a robust developmental module

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

1 reference

7 January 2021

How many diseases does it take to map a gene with SNPs?

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Highly conserved non-coding sequences are associated with vertebrate development

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

Analysis of regulatory network topology reveals functionally distinct classes of microRNAs.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2809%2978003-7

7 January 2021

10.1016/S1937-6448(09)78003-7

Identifiers

DOI

1 reference

21 August 2017

1 reference