(Q37611857)

21 August 2017

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title

Role of gut microbiota in Crohn's disease (English)

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21 August 2017

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3

Lynnette R Ferguson

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21 August 2017

2

Donald R Love

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21 August 2017

Phillip I Baker

1

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21 August 2017

1 October 2009

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Expert Review of Gastroenterology & Hepatology

21 August 2017

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21 August 2017

3

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21 August 2017

535-546

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21 August 2017

5

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How host-microbial interactions shape the nutrient environment of the mammalian intestine

21 August 2017

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Modification of intestinal flora in the treatment of inflammatory bowel disease

21 January 2018

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Reduced mucosal antimicrobial activity in Crohn's disease of the colon

21 January 2018

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Interleukin-10-deficient mice develop chronic enterocolitis

21 January 2018

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Commensal bacteria, traditional and opportunistic pathogens, dysbiosis and bacterial killing in inflammatory bowel diseases

21 January 2018

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A microbial symbiosis factor prevents intestinal inflammatory disease

21 January 2018

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Mycobacterium avium subspecies paratuberculosis and Crohn's disease: a systematic review and meta-analysis

21 January 2018

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The Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 replicates in mature phagolysosomes within J774 macrophages.

21 January 2018

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Low counts of Faecalibacterium prausnitzii in colitis microbiota.

21 January 2018

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Mycobacterium avium subspecies paratuberculosis infection in cases of irritable bowel syndrome and comparison with Crohn's disease and Johne's disease: common neural and immune pathogenicities

21 January 2018

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Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases

21 January 2018

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Differential release and distribution of Nod1 and Nod2 immunostimulatory molecules among bacterial species and environments.

21 January 2018

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Host-bacterial mutualism in the human intestine

21 January 2018

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Commensal host-bacterial relationships in the gut

21 January 2018

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Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells

21 January 2018

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Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

21 January 2018

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

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A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

21 January 2018

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A Nonsynonymous SNP in ATG16L1 Predisposes to Ileal Crohn’s Disease and Is Independent of CARD15 and IBD5

21 January 2018

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Intestinal epithelial cells as watchdogs for the natural immune system

21 January 2018

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Innate immune recognition

21 January 2018

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Reduced Paneth cell alpha-defensins in ileal Crohn's disease

21 January 2018

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Bacterial interactions with cells of the intestinal mucosa: Toll-like receptors and NOD2

21 January 2018

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Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2.

21 January 2018

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Immunology of Crohn's Disease

21 January 2018

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Ecological and evolutionary forces shaping microbial diversity in the human intestine

21 January 2018

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Diversity of the human intestinal microbial flora

21 January 2018

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Microbial ecology: human gut microbes associated with obesity

21 January 2018

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Molecular analysis of commensal host-microbial relationships in the intestine

21 January 2018

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A molecular sensor that allows a gut commensal to control its nutrient foundation in a competitive ecosystem

21 January 2018

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Bacterial contributions to mammalian gut development

21 January 2018

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Obesity alters gut microbial ecology

21 January 2018

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Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination.

21 January 2018

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Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA.

21 January 2018

1 reference

Antagonist. Mycobacterium avium subspecies paratuberculosis is a cause of Crohn's disease

21 January 2018

1 reference

Study of Animal-Borne Infections in the Mucosas of Patients with Inflammatory Bowel Disease and Population-Based Controls

21 January 2018

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XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

21 January 2018

1 reference

Genes, diet and inflammatory bowel disease.

21 January 2018

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A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon

21 January 2018

1 reference

NOD2 mutations and Crohn's disease: are Paneth cells and their antimicrobial peptides the link?

21 January 2018

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Crystal structures of human alpha-defensins HNP4, HD5, and HD6

21 January 2018

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Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria

21 January 2018

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Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense

21 January 2018

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Paneth cells, defensins, and the commensal microbiota: a hypothesis on intimate interplay at the intestinal mucosa

21 January 2018

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Rationale for probiotic treatment strategies in inflammatory bowel disease

21 January 2018

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Interactions among genes influencing bacterial recognition increase IBD risk in a population-based New Zealand cohort.

21 January 2018

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Probiotic E. coli treatment mediates antimicrobial human beta-defensin synthesis and fecal excretion in humans.

21 January 2018

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Epidemiology of inflammatory bowel disease in a German twin cohort: results of a nationwide study

21 January 2018

1 reference

Molecular analysis of the gut microbiota of identical twins with Crohn's disease

21 January 2018

1 reference

Altered permeability in inflammatory bowel disease: pathophysiology and clinical implications

21 January 2018

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Intelectin: a novel lipid raft-associated protein in the enterocyte brush border

21 January 2018

1 reference

Human IRGM induces autophagy to eliminate intracellular mycobacteria

21 January 2018

1 reference

Autophagy in the Pathogenesis of Disease

21 January 2018

1 reference

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

21 January 2018

1 reference

Association of the T300A non-synonymous variant of the ATG16L1 gene with susceptibility to paediatric Crohn's disease

21 January 2018

1 reference

Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients

21 January 2018

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Autophagy in innate immunity against intracellular bacteria

21 January 2018

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Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

21 January 2018

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Nutrient control of macroautophagy in mammalian cells.

21 January 2018

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IMMUNOLOGY: Eating In to Avoid Infection

21 January 2018

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Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity

21 January 2018

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Confirmation of association of IRGM and NCF4 with ileal Crohn's disease in a population-based cohort

21 January 2018

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Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

21 January 2018

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Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection

21 January 2018

1 reference

Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells

21 January 2018

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Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

21 January 2018

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Kinase activity of mutant LRRK2 mediates neuronal toxicity

21 January 2018

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Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection

21 January 2018

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21 January 2018

1 reference

Toll-like receptors in the induction of the innate immune response

21 January 2018

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Host-bacterial interactions in inflammatory bowel disease

21 January 2018

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RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

21 January 2018

1 reference

Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

21 January 2018

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NOD2 contributes to cutaneous defense against Staphylococcus aureus through alpha-toxin-dependent innate immune activation

21 January 2018

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NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

21 January 2018

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The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

21 January 2018

1 reference

Nucleotide-binding oligomerization domain containing 1 (NOD1) haplotypes and single nucleotide polymorphisms modify susceptibility to inflammatory bowel diseases in a New Zealand caucasian population: a case-control study

21 January 2018

1 reference

Genetic variants of Wnt transcription factor TCF-4 (TCF7L2) putative promoter region are associated with small intestinal Crohn's disease

21 January 2018

1 reference

NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression

21 January 2018

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CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease

21 January 2018

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Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study

21 January 2018

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Association of beta-defensin 1 single nucleotide polymorphisms with Crohn's disease

21 January 2018

1 reference

Confirmation of the role of ATG16l1 as a Crohnʼs disease susceptibility gene

21 January 2018

1 reference

Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohn's disease

21 January 2018

1 reference

Crohn's disease: genetic susceptibility, bacteria, and innate immunity

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/EGH.09.47

1 reference

21 August 2017

1 reference

PubMed ID

19817674