(Q37611865)

21 August 2017

1 reference

title

Modulation of UDP-glucuronosyltransferase activity by protein-protein association (English)

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21 August 2017

Yuji Ishii

1

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21 August 2017

Shuso Takeda

series ordinal

2

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21 August 2017

Hideyuki Yamada

series ordinal

3

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21 August 2017

language of work or name

English

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publication date

1 February 2010

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21 August 2017

Drug Metabolism Reviews

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21 August 2017

42

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21 August 2017

1

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21 August 2017

145-158

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Isolation and characterization of a human orphan UDP-glucuronosyltransferase, UGT2B11.

21 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Purification of Rat-Liver Microsomal UDP-glucuronyltransferase. Separation of Two Enzyme Forms Inducible by 3-Methylcholanthrene or Phenobarbital

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Topological aspects of oligomeric UDP-glucuronosyltransferases in endoplasmic reticulum membranes: advances and open questions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Activation and induction of rat liver microsomal UDP-glucuronyltransferase with 3-hydroxybenzo(a)pyrene and N-hydroxy-2-naphthylamine as substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Engineering microsomal cytochrome P450 2C5 to be a soluble, monomeric enzyme. Mutations that alter aggregation, phospholipid dependence of catalysis, and membrane binding

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Pharmacogenomics: translating functional genomics into rational therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

The UDP-glucuronosyltransferases as oligomeric enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Epoxide hydrolases: biochemistry and molecular biology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Interactions between human UGT1A1, UGT1A4, and UGT1A6 affect their enzymatic activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Effects of coexpression of UGT1A9 on enzymatic activities of human UGT1A isoforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Homodimerization of human bilirubin-uridine-diphosphoglucuronate glucuronosyltransferase-1 (UGT1A1) and its functional implications

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Genetic diversity at the UGT1 locus is amplified by a novel 3' alternative splicing mechanism leading to nine additional UGT1A proteins that act as regulators of glucuronidation activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Identification of a rat oltipraz-inducible UDP-glucuronosyltransferase (UGT1A7) with activity towards benzo(a)pyrene-7,8-dihydrodiol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Functional co-expression of xenobiotic metabolizing enzymes, rat cytochrome P450 1A1 and UDP-glucuronosyltransferase 1A6, in yeast microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Protein-protein interactions between rat hepatic cytochromes P450 (P450s) and UDP-glucuronosyltransferases (UGTs): evidence for the functionally active UGT in P450-UGT complex

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Characterization of the renal tubular transport of zonampanel, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist, by human organic anion transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Functional protein-protein interaction of drug metabolizing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Molecular mechanism of phase I and phase II drug-metabolizing enzymes: implications for detoxification

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Membrane properties induced by anionic phospholipids and phosphatidylethanolamine are critical for the membrane binding and catalytic activity of human cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Species difference of site-selective glucuronidation of morphine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Expression and characterization of recombinant human UDP-glucuronosyltransferases (UGTs). UGT1A9 is more resistant to detergent inhibition than other UGTs and was purified as an active dimeric enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

The interactions between the N-terminal and C-terminal domains of the human UDP-glucuronosyltransferases are partly isoform-specific, and may involve both monomers.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

An active and water-soluble truncation mutant of the human UDP-glucuronosyltransferase 1A9.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Interactions with other human UDP-glucuronosyltransferases attenuate the consequences of the Y485D mutation on the activity and substrate affinity of UGT1A6.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Structure-activity relationship for human cytochrome P450 substrates and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Regulation of the UGT1A1 bilirubin-conjugating pathway: role of a new splicing event at the UGT1A locus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Genetic deficiency of androsterone UDP-glucuronosyltransferase activity in Wistar rats is due to the loss of enzyme protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Structure and function of uridine diphosphate glucuronosyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Determinants of UDP glucuronosyltransferase membrane association and residency in the endoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Mutational analysis of the carboxy-terminal region of UDP-glucuronosyltransferase 2B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Human UGT1A6 pharmacogenetics: identification of a novel SNP, characterization of allele frequencies and functional analysis of recombinant allozymes in human liver tissue and in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Stereoselective glucuronidation of 5-(4'-hydroxyphenyl)-5-phenylhydantoin by human UDP-glucuronosyltransferase (UGT) 1A1, UGT1A9, and UGT2B15: effects of UGT-UGT interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Regiochemistry of cytochrome P450 isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

A historical overview of the heterologous expression of mammalian UDP-glucuronosyltransferase isoforms over the past twenty years.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

The mammalian carboxylesterases: from molecules to functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

An investigation of the transverse topology of bilirubin UDP-glucuronosyltransferase in rat hepatic endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

The effect of incubation conditions on the enzyme kinetics of udp-glucuronosyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Modulation of UDP-glucuronosyltransferase function by cytochrome P450: evidence for the alteration of UGT2B7-catalyzed glucuronidation of morphine by CYP3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Modulation of UDP-glucuronosyltransferase 2B7 function by cytochrome P450s in vitro: differential effects of CYP1A2, CYP2C9 and CYP3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Interaction of cytochrome P450 3A4 and UDP-glucuronosyltransferase 2B7: evidence for protein-protein association and possible involvement of CYP3A4 J-helix in the interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Cytochrome P450 1A1 (CYP1A1) inhibitor alpha-naphthoflavone interferes with UDP-glucuronosyltransferase (UGT) activity in intact but not in permeabilized hepatic microsomes from 3-methylcholanthrene-treated rats: possible involvement of UGT-P450 int

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Interaction between cytochrome P450 and other drug-metabolizing enzymes: evidence for an association of CYP1A1 with microsomal epoxide hydrolase and UDP-glucuronosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Topology and regulation of bilirubin UDP-glucuronyltransferase in sealed native microsomes from rat liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Nomenclature for N-acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

Crystal structure-based studies of cytosolic sulfotransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903208579

10.3109/03602530903208579

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

1 reference