(Q37613081)

English

Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain.

scientific article published on 18 April 2013

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scholarly article

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29 February 2020

Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain (English)

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29 February 2020

Alzheimer's disease

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inferred from title

Fabio Di Domenico

1

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29 February 2020

Raffaella Coccia

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29 February 2020

Giovanna Cenini

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29 February 2020

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29 February 2020

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Annalisa Cocciolo

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29 February 2020

M Paul Murphy

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29 February 2020

Elizabeth Head

6

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29 February 2020

Alessandra Giorgi

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29 February 2020

Maria Eugenia Schinina

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29 February 2020

Marzia Perluigi

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29 February 2020

D Allan Butterfield

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18 April 2013

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29 February 2020

Biochimica et Biophysica Acta

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29 February 2020

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29 February 2020

1249-1259

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29 February 2020

8

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29 February 2020

Down's syndrome and Alzheimer's disease: towards secondary prevention

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23 August 2017

Oxidative Stress and Down Syndrome: A Route toward Alzheimer-Like Dementia

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Redox proteomics in selected neurodegenerative disorders: from its infancy to future applications.

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Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome

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23 August 2017

Plasma amyloid-β as a function of age, level of intellectual disability, and presence of dementia in Down syndrome

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23 August 2017

Identification of regulators of chaperone-mediated autophagy

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Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations

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Oxidatively modified, mitochondria-relevant brain proteins in subjects with Alzheimer disease and mild cognitive impairment

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Biomarkers of oxidative and nitrosative damage in Alzheimer's disease and mild cognitive impairment

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Proteomics-determined differences in the concanavalin-A-fractionated proteome of hippocampus and inferior parietal lobule in subjects with Alzheimer's disease and mild cognitive impairment: implications for progression of AD.

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Down syndrome fibroblast model of Alzheimer-related endosome pathology: accelerated endocytosis promotes late endocytic defects

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The role of ubiquitin C-terminal hydrolase L1 in neurodegenerative disorders

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Possible compensatory events in adult Down syndrome brain prior to the development of Alzheimer disease neuropathology: targets for nonpharmacological intervention.

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Autophagy as a cell-repair mechanism: activation of chaperone-mediated autophagy during oxidative stress

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Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase

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Endoplasmic reticulum stress triggers autophagy

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Activation of chaperone-mediated autophagy during oxidative stress

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Down syndrome and beta-amyloid deposition

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Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1.

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Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide

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Protein quality control in neurodegenerative disease

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Oxidative stress and mitochondrial dysfunction in Down syndrome.

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6 September 2017

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6 September 2017

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25 June 2018

Prospective study of the prevalence of Alzheimer-type dementia in institutionalized individuals with Down syndrome.

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25 June 2018

Alzheimer's disease in Down's syndrome: clinicopathologic studies

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25 June 2018

The topography of plaques and tangles in Down's syndrome patients of different ages

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25 June 2018

The effect of mixed-function oxidation of enzymes on their susceptibility to degradation by a nonlysosomal cysteine proteinase

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25 June 2018

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25 June 2018

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25 June 2018

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NAP and ADNF-9 protect normal and Down's syndrome cortical neurons from oxidative damage and apoptosis.

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1 September 2018

Redox proteomics identification of oxidatively modified brain proteins in inherited Alzheimer's disease: an initial assessment.

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1 September 2018

Proteomic analysis of glial fibrillary acidic protein in Alzheimer's disease and aging brain.

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1 September 2018

Proteomic identification of proteins oxidized by Abeta(1-42) in synaptosomes: implications for Alzheimer's disease

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1 September 2018

Abeta localization in abnormal endosomes: association with earliest Abeta elevations in AD and Down syndrome.

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1 September 2018

An altered antioxidant balance occurs in Down syndrome fetal organs: implications for the "gene dosage effect" hypothesis.

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1 September 2018

Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases

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1 September 2018

Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome

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1 September 2018

Early amyloid deposition in the medial temporal lobe of young Down syndrome patients: a regional quantitative analysis.

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1 September 2018

Early glycoxidation damage in brains from Down's syndrome.

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1 September 2018

Differential susceptibility to neurofibrillary pathology among patients with Down syndrome.

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1 September 2018

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro.

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1 September 2018

Free radical damage in Down's syndrome brain.

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1 September 2018

Exposure of hydrophobic moieties promotes the selective degradation of hydrogen peroxide-modified hemoglobin by the multicatalytic proteinase complex, proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940071

1 September 2018

Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: evidence for early up-regulation of the endosomal-lysosomal system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940071

1 September 2018

Impaired proteasome function in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23603808

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patterns of gliosis in Alzheimer's disease and aging cerebrum

1 reference

https://pubmed.ncbi.nlm.nih.gov/23603808

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23603808

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress occurs early in Down syndrome pregnancy: A redox proteomics analysis of amniotic fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/23603808

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BBADIS.2013.04.013

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23603808%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23603808%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23603808%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

ResearchGate publication ID

0 references

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