(Q37618284)

21 August 2017

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title

Cholesterol oxidase: biochemistry and structural features (English)

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21 August 2017

Alice Vrielink

1

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21 August 2017

Sandro Ghisla

series ordinal

2

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21 August 2017

language of work or name

English

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publication date

16 October 2009

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21 August 2017

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21 August 2017

volume

276

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21 August 2017

issue

23

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21 August 2017

page(s)

6826-6843

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Cholesterol oxidase: a potent insecticidal protein active against boll weevil larvae

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Expression and chloroplast targeting of cholesterol oxidase in transgenic tobacco plants

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Cholesterol oxidase and resistance of Rhodococcus equi to peroxidative stress in vitro in the presence of cholesterol

21 January 2018

1 reference

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Oxygen access to the active site of cholesterol oxidase through a narrow channel is gated by an Arg-Glu pair

21 January 2018

1 reference

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Crystal structure of cholesterol oxidase from Brevibacterium sterolicum refined at 1.8 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Sub-atomic resolution crystal structure of cholesterol oxidase: what atomic resolution crystallography reveals about enzyme mechanism and the role of the FAD cofactor in redox activity

21 January 2018

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On the oxygen reactivity of flavoprotein oxidases: an oxygen access tunnel and gate in brevibacterium sterolicum cholesterol oxidase.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

The Binding and Release of Oxygen and Hydrogen Peroxide Are Directed by a Hydrophobic Tunnel in Cholesterol Oxidase †

21 January 2018

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Clustal W and Clustal X version 2.0

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Structural and kinetic analyses of the H121A mutant of cholesterol oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Purification and some properties of cholesterol oxidase stable in detergents from gamma-proteobacterium Y-134.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Reversible resolution of flavoproteins into apoproteins and fee flavins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Dissecting the structural determinants of the stability of cholesterol oxidase containing covalently bound flavin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Relevance of the flavin binding to the stability and folding of engineered cholesterol oxidase containing noncovalently bound FAD.

21 January 2018

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Cholesterol oxidase from Brevibacterium sterolicum. The relationship between covalent flavinylation and redox properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

A hydrogen-bonding network is important for oxidation and isomerization in the reaction catalyzed by cholesterol oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

On the interpretation of the absorption spectra of flavoproteins with special reference to D-amino acid oxidase

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

New flavins for old: artificial flavins as active site probes of flavoproteins

21 January 2018

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The Evolution of Dehydrogenases and Kinase

21 January 2018

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The alpha-helix dipole and the properties of proteins

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants

21 January 2018

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GMC oxidoreductases. A newly defined family of homologous proteins with diverse catalytic activities.

21 January 2018

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Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

What's in a covalent bond? On the role and formation of covalently bound flavin cofactors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Mechanism of action of methanol oxidase, reconstitution of methanol oxidase with 5-deazaflavin, and inactivation of methanol oxidase by cyclopropanol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Flavin-dependent alcohol oxidase from yeast. Studies on the catalytic mechanism and inactivation during turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Structural analysis of the catalytic mechanism and stereoselectivity in Streptomyces coelicolor alditol oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Carbanion versus hydride transfer mechanisms in flavoprotein-catalyzed dehydrogenations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

On the reaction mechanism of L-lactate oxidase: quantitative structure-activity analysis of the reaction with para-substituted L-mandelates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Cholesterol oxidases: a study of nature's approach to protein design

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Altered substrate specificity in flavocytochrome b2: structural insights into the mechanism of L-lactate dehydrogenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Structural bases of hydrogen tunneling in enzymes: progress and puzzles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Hydrogen tunneling in enzyme reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Structure of the pyrroloquinoline quinone radical in quinoprotein ethanol dehydrogenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Mechanistic and Structural Studies of H373Q Flavocytochrome b 2 : Effects of Mutating the Active Site Base † , ‡

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Tunneling and dynamics in enzymatic hydride transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Crystal structure of cholesterol oxidase complexed with a steroid substrate: implications for flavin adenine dinucleotide dependent alcohol oxidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Separation of the two reactions, oxidation and isomerization, catalyzed by Streptomyces cholesterol oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Distortion of flavin geometry is linked to ligand binding in cholesterol oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

The presence of a hydrogen bond between asparagine 485 and the pi system of FAD modulates the redox potential in the reaction catalyzed by cholesterol oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Effect of non-ionic detergents on apparent enzyme mechanism: V121A mutant of Streptomyces cholesterol oxidase endowed with enhanced sensitivity towards detergents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Cholesterol oxidase senses subtle changes in lipid bilayer structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Library screening studies to investigate substrate specificity in the reaction catalyzed by cholesterol oxidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Assessment of the role of an omega loop of cholesterol oxidase: a truncated loop mutant has altered substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Alteration of substrate specificity of cholesterol oxidase from Streptomyces sp. by site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Mechanisms of flavoprotein-catalyzed reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

The chemical and biological versatility of riboflavin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Ever-fluctuating single enzyme molecules: Michaelis-Menten equation revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Functional conformational motions in the turnover cycle of cholesterol oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Single-molecule enzymatic dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Single-molecule enzymology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Acyl-CoA dehydrogenases. A mechanistic overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Involvement of Sox-4 in the cytochrome c-dependent AIF-independent apoptotic pathway in HeLa cells induced by Delta12-prostaglandin J2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Quenching of fluorescence by oxygen. Probe for structural fluctuations in macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Quenching of protein fluorescence by oxygen. Detection of structural fluctuations in proteins on the nanosecond time scale.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Monomer-dimer equilibrium and oxygen binding properties of ferrous Vitreoscilla hemoglobin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Structure at 2.8 A resolution of cytochrome c oxidase from Paracoccus denitrificans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Structure of Salmonella typhimurium nrdF ribonucleotide reductase in its oxidized and reduced forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Structure and mechanism of the aberrant ba3-cytochrome c oxidase from Thermus thermophilus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

The high-resolution X-ray crystallographic structure of the ferritin (EcFtnA) of Escherichia coli; comparison with human H ferritin (HuHF) and the structures of the Fe(3+) and Zn(2+) derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Molecular dioxygen enters the active site of 12/15-lipoxygenase via dynamic oxygen access channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

Crystal structure of LAAO from Calloselasma rhodostoma with an L-phenylalanine substrate: insights into structure and mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07377.X

10.1111/J.1742-4658.2009.07377.X

21 January 2018

Identifiers

DOI

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21 August 2017

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